Siddique AB, Kilgore PCSR, Tajmim A, Singh SS, Meyer SA, Jois SD, Cvek U, Trutschl M, Sayed KAE.,
(-)-Oleocanthal as a Dual c-MET-COX2 Inhibitor for the Control of Lung Cancer, Nutrients. 2020 Jun 11;12(6):1749. doi: 10.3390/nu12061749.
Masoodi, K. Z., Ramos Garcia, R., Pascal, L. E., Wang, Y., Ma, H. M., O'Malley, K., . . . Wang, Z. (2013).,
5alpha-reductase inhibition suppresses testosterone-induced initial regrowth of regressed xenograft prostate tumors in animal models., Endocrinology, 154(7), 2296-2307. doi:10.1210/en.2012-2077 [doi]
杨,称赞;俞、张;江,Yongying;毛,Weiqun; Pang, Lan; Redwood, Abena; Jeter-Jones, Sabrina L; Jennings, Nicholas B; Ornelas, Argentina; Zhou, Jinhua; Rodriguez-Aguayo, Cristian; Bartholomeusz, Geoffrey; Iles, LaKesla R; Zacharias, Niki M; Millward, Steven W; Lopez-Berestein, Gabriel; Le, Xiao-Feng; Ahmed, Ahmed A; Piwnica-Worms, Helen; Sood, Anil K; Bast, Robert C; Lu, Zhen,
6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase-2 Regulates TP53-Dependent Paclitaxel Sensitivity in Ovarian and Breast Cancers, Clinical cancer research : an official journal of the American Association for Cancer Research Vol.25, 2019
Marayati R,鲍恩LV, Stafman LL,威廉姆斯美联社inn CH, Atigadda V, Aye JM, Stewart JE, Yoon KJ, Beierle EA.,
9-cis-UAB30, a novel rexinoid agonist, decreases tumorigenicity and cancer cell stemness of human neuroblastoma patient-derived xenografts, Transl Oncol. 2021 Jan;14(1):100893. doi: 10.1016/j.tranon.2020.100893. Epub 2020 Sep 30.
Deng, Y., Wang, Z., Zhang, F., Qiao, M., Yan, Z., Wei, Q., . . . Zhang, J. (2016),
A blockade of IGF signaling sensitizes human ovarian cancer cells to the anthelmintic niclosamide-induced anti-proliferative and anticancer activities, Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 39(3), 871-888. doi:10.1159/000447797 [doi]
Luderer, M. J., Muz, B., de la Puente, P., Chavalmane, S., Kapoor, V., Marcelo, R., . . . Azab, A. K. (2016),
A hypoxia-targeted boron neutron capture therapy agent for the treatment of glioma., Pharmaceutical Research, 33(10), 2530-2539. doi:10.1007/s11095-016-1977-2 [doi]
Hight, M. R., Cheung, Y. Y., Nickels, M. L., Dawson, E. S., Zhao, P., Saleh, S., . . . Manning, H. C. (2014).,
A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 20(8), 2126-2135. doi:10.1158/1078-0432.CCR-13-2444 [doi]
Dey, J., Kerwin, W. S., Grenley, M. O., Casalini, J. R., Tretyak, I., Ditzler, S. H., . . . Klinghoffer, R. A. (2016),
A platform for rapid, quantitative assessment of multiple drug combinations simultaneously in solid tumors in vivo., PloS One, 11(6), e0158617. doi:10.1371/journal.pone.0158617 [doi]
Green, D. J., Orgun, N. N., Jones, J. C., Hylarides, M. D., Pagel, J. M., Hamlin, D. K., . . . Press, O. W. (2014),
A preclinical model of CD38-pretargeted radioimmunotherapy for plasma cell malignancies., Cancer Research, 74(4), 1179-1189. doi:10.1158/0008-5472.CAN-13-1589 [doi]
Neiveyans, Madeline; Melhem, Rana; Arnoult, Christophe; Bourquard, Thomas; Jarlier, Marta; Busson, Muriel; Laroche, Adrien; Cerutti, Martine; Pugnière, Martine; Ternant, David; Gaborit, Nadège; Chardès, Thierry; Poupon, Anne; Gouilleux-Gruart, Valérie; Pèlegrin, Andre; Poul, Marie-Alix;,
A recycling anti-transferrin receptor-1 monoclonal antibody as an efficient therapy for erythroleukemia through target up-regulation and antibody-dependent cytotoxic effector functions, mAbs Vol.11, 2019
Santich BH,母婴感染SM艾哈迈德·M化先生,Ouerfelli O, Yang G, Veach DR, Fung EK, Patel M, Burnes Vargas D, Malik AA, Guo HF, Zanzonico PB, Monette S, Michel AO, Rudin CM, Larson SM, Cheung NK.,
A Self-Assembling and Disassembling (SADA) Bispecific Antibody (BsAb) Platform for Curative Two-step Pretargeted Radioimmunotherapy, Clin Cancer Res. 2020 Sep 21. doi: 10.1158/1078-0432.CCR-20-2150. Online ahead of print.
Roy, L. D., Dillon, L. M., Zhou, R., Moore, L. J., Livasy, C., El-Khoury, J. M., . . . Mukherjee, P. (2017).,
A tumor specific antibody to aid breast cancer screening in women with dense breast tissue., Genes & Cancer, 8(3-4), 536-549. doi:10.18632/genesandcancer.134 [doi]
Kim, S. S., Rait, A., Kim, E., Pirollo, K. F., & Chang, E. H. (2015).,
A tumor-targeting p53 nanodelivery system limits chemoresistance to temozolomide prolonging survival in a mouse model of glioblastoma multiforme., Nanomedicine : Nanotechnology, Biology, and Medicine, 11(2), 301-311. doi:10.1016/j.nano.2014.09.005 [doi]
Formisano, Luigi; Lu, Yao; Servetto, Alberto; Hanker, Ariella B; Jansen, Valerie M; Bauer, Joshua A; Sudhan, Dhivya R; Guerrero-Zotano, Angel L; Croessmann, Sarah; Guo, Yan; Ericsson, Paula Gonzalez; Lee, Kyung-Min; Nixon, Mellissa J; Schwarz, Luis J; Sanders, Melinda E; Dugger, Teresa C; Cruz, Marcelo Rocha; Behdad, Amir; Cristofanilli, Massimo; Bardia, Aditya; OShaughnessy, Joyce; Nagy, Rebecca J; Lanman, Richard B; Solovieff, Nadia; He, Wei; Miller, Michelle; Su, Fei; Shyr, Yu; Mayer, Ingrid A; Balko, Justin M; Arteaga, Carlos L;,
Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer., Nature communications Vol.10, 2019
Tansi、F L。鲁格,R,玻姆,C, Steiniger, F。,Kontermann, R. E., Teichgraeber, U. K., . . . Hilger, I. (2017).,
Activatable bispecific liposomes bearing fibroblast activation protein directed single chain fragment/Trastuzumab deliver encapsulated cargo into the nuclei of tumor cells and the tumor microenvironment simultaneously., Acta Biomaterialia, 54, 281-293. doi:S1742-7061(17)30203-9 [pii]
Young, N. R., Soneru, C., Liu, J., Grushko, T. A., Hardeman, A., Olopade, O. I., . . . Cohen, E. E. (2015).,
Afatinib efficacy against squamous cell carcinoma of the head and neck cell lines in vitro and in vivo.靶向肿瘤,10(4),501 - 508。doi: 10.1007 / s11523-014-0353-6 [doi]
Ziegler, J., Bastian, A., Lerner, M., Bailey-Downs, L., Saunders, D., Smith, N., . . . Towner, R. A. (2017).,
AG488 as a therapy against gliomas., Oncotarget, 8(42), 71833-71844. doi:10.18632/oncotarget.18284 [doi]
Gomes AP, Ilter D, Low V, Endress JE, Fernández-García J, Rosenzweig A, Schild T, Broekaert D, Ahmed A, Planque M, Elia I, Han J, Kinzig C, Mullarky E, Mutvei AP, Asara J, de Cabo R, Cantley LC, Dephoure N, Fendt SM, Blenis J.,
Age-induced accumulation of methylmalonic acid promotes tumour progression, Nature. 2020 Sep;585(7824):283-287. doi: 10.1038/s41586-020-2630-0. Epub 2020 Aug 19.
Sun Y, Meyers BA, Czako B, Leonard P, Mseeh F, Harris AL, Wu Q, Johnson S, Parker CA, Cross JB, Di Francesco ME, Bivona BJ, Bristow CA, Burke JP, Carrillo CC, Carroll CL, Chang Q, Feng N, Gao G, Gera S, Giuliani V, Huang JK, Jiang Y, Kang Z, Kovacs JJ, Liu CY, Lopez AM, Ma X, Mandal PK, McAfoos T, Miller MA, Mullinax RA, Peoples M, Ramamoorthy V, Seth S, Spencer ND, Suzuki E, Williams CC, Yu SS, Zuniga AM, Draetta GF, Marszalek JR, Heffernan TP, Kohl NE, Jones P.,
Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib, Cancer Res. 2020 Nov 1;80(21):4840-4853. doi: 10.1158/0008-5472.CAN-20-1634. Epub 2020 Sep 14.
Zhang, R., Pan, D., Cai, X., Yang, X., Senpan, A., Allen, J. S., . . . Wang, L. V. (2015),
alphaVbeta3-targeted copper nanoparticles incorporating an sn 2 lipase-labile fumagillin prodrug for photoacoustic neovascular imaging and treatment., Theranostics, 5(2), 124-133. doi:10.7150/thno.10014 [doi]
Bush, T. L., Payton, M., Heller, S., Chung, G., Hanestad, K., Rottman, J. B., . . . Radinsky, R. (2013),
AMG 900极光基那的小分子抑制剂ses, potentiates the activity of microtubule-targeting agents in human metastatic breast cancer models, Molecular Cancer Therapeutics, 12(11), 2356-2366. doi:10.1158/1535-7163.MCT-12-1178 [doi]
Asundi, J., Crocker, L., Tremayne, J., Chang, P., Sakanaka, C., Tanguay, J., . . . Firestein, R. (2015),
An antibody-drug conjugate directed against lymphocyte antigen 6 complex, locus E (LY6E) provides robust tumor killing in a wide range of solid tumor malignancies., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(14), 3252-3262. doi:10.1158/1078-0432.CCR-15-0156 [doi]
Citron, F., Armenia, J., Franchin, G., Polesel, J., Talamini, R., D'Andrea, S., . . . Baldassarre, G. (2017),
An integrated approach identifies mediators of local recurrence in head and neck squamous carcinoma, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(14), 3769-3780. doi:10.1158/1078-0432.CCR-16-2814 [doi]
Zhang, F., Li, Y., Zhang, H., Huang, E., Gao, L., Luo, W., . . . Ji, P. (2017).,
Anthelmintic mebendazole enhances cisplatin's effect on suppressing cell proliferation and promotes differentiation of head and neck squamous cell carcinoma (HNSCC)., Oncotarget, 8(8), 12968-12982. doi:10.18632/oncotarget.14673 [doi]
Miles, L. A., Burga, L. N., Gardner, E. E., Bostina, M., Poirier, J. T., & Rudin, C. M. (2017).,
Anthrax toxin receptor 1 is the cellular receptor for seneca valley virus., The Journal of Clinical Investigation, 127(8), 2957-2967. doi:10.1172/JCI93472 [doi]
Moody, G., Belmontes, B., Masterman, S., Wang, W., King, C., Murawsky, C., . . . Beltran, P. J. (2016).,
Antibody-mediated neutralization of autocrine Gas6 inhibits the growth of pancreatic ductal adenocarcinoma tumors in vivo, International Journal of Cancer, 139(6), 1340-1349. doi:10.1002/ijc.30180 [doi]
Tabernero, J., Chawla, S. P., Kindler, H., Reckamp, K., Chiorean, E. G., Azad, N. S., . . . Baselga, J. (2015).,
Anticancer activity of the type I insulin-like growth factor receptor antagonist, ganitumab, in combination with the death receptor 5 agonist, conatumumab., argeted Oncology, 10(1), 65-76. doi:10.1007/s11523-014-0315-z [doi]
Li, X., Wu, J. B., Chung, L. W., & Huang, W. C. (2015).,
Anti-cancer efficacy of SREBP inhibitor, alone or in combination with docetaxel, in prostate cancer harboring p53 mutations.Oncotarget 6(38), 41018 - 41032。doi: 10.18632 / oncotarget.5879 [doi]
Yan, H., Kapoor, V., Nguyen, K., Akers, W. J., Li, H., Scott, J., . . . Hallahan, D. (2016).,
Anti-tax interacting protein-1 (TIP-1) monoclonal antibody targets human cancers., Oncotarget, 7(28), 43352-43362. doi:10.18632/oncotarget.9713 [doi]
Juzeniene, A., Bernoulli, J., Suominen, M., Halleen, J., & Larsen, R. H. (2018).,
Antitumor activity of novel bone-seeking, alpha-emitting (224)ra-solution in a breast cancer skeletal metastases model, Anticancer Research, 38(4), 1947-1955. doi:38/4/1947 [pii]
Zumwalt, T. J., Wodarz, D., Komarova, N. L., Toden, S., Turner, J., Cardenas, J., . . . Goel, A. (2017).,
Aspirin-induced chemoprevention and response kinetics are enhanced by PIK3CA mutations in colorectal cancer cells., Cancer Prevention Research (Philadelphia, Pa.), 10(3), 208-218. doi:10.1158/1940-6207.CAPR-16-0175 [doi]
绿色,d J。,Shadman, M,琼斯,J . C。Frayo, S。L., Kenoyer, A. L., Hylarides, M. D., . . . Press, O. W. (2015).,
Astatine-211 conjugated to an anti-CD20 monoclonal antibody eradicates disseminated B-cell lymphoma in a mouse model, Blood, 125(13), 2111-2119. doi:10.1182/blood-2014-11-612770 [doi]
Yeo, S. K., Wen, J., Chen, S., & Guan, J. L. (2016).,
Autophagy differentially regulates distinct breast cancer stem-like cells in murine models via EGFR/Stat3 and Tgfbeta/Smad signaling, Cancer Research, 76(11), 3397-3410. doi:10.1158/0008-5472.CAN-15-2946 [doi]
Wang Y, Xie W, Humeau J, Chen G, Liu P, Pol J, Zhang Z, Kepp O, Kroemer G.,
Autophagy induction by thiostrepton improves the efficacy of immunogenic chemotherapy, J Immunother Cancer. 2020 Mar;8(1):e000462. doi: 10.1136/jitc-2019-000462.
Loddick, S. A., Ross, S. J., Thomason, A. G., Robinson, D. M., Walker, G. E., Dunkley, T. P., . . . Brooks, A. N. (2013).,
AZD3514: A small molecule that modulates androgen receptor signaling and function in vitro and in vivo., Molecular Cancer Therapeutics, 12(9), 1715-1727. doi:10.1158/1535-7163.MCT-12-1174 [doi]
Fok, Jacqueline H L; Ramos-Montoya, Antonio; Vazquez-Chantada, Mercedes; Wijnhoven, Paul W G; Follia, Valeria; James, Neil; Farrington, Paul M; Karmokar, Ankur; Willis, Sophie E; Cairns, Jonathan; Nikkilä, Jenni; Beattie, David; Lamont, Gillian M; Finlay, M Raymond V; Wilson, Joanne; Smith, Aaron; OConnor, Lenka Oplustil; Ling, Stephanie; Fawell, Stephen E; OConnor, Mark J; Hollingsworth, Simon J; Dean, Emma; Goldberg, Frederick W; Davies, Barry R; Cadogan, Elaine B;,
AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity., Nature communications Vol.10, 2019
Rello-Varona, Santi; Fuentes-Guirado, Miriam; López-Alemany, Roser; Contreras-Pérez, Aida; Mulet-Margalef, Núria; García-Monclús, Silvia; Tirado, Oscar M; García Del Muro, Xavier,
Bcl-xL inhibition enhances Dinaciclib-induced cell death in soft-tissue sarcomas, Scientific reports Vol.9, 2019
San Millan, C., Soldevilla, B., Martin, P., Gil-Calderon, B., Compte, M., Perez-Sacristan, B., . . . Dominguez, G. (2015),
Beta-cryptoxanthin synergistically enhances the antitumoral activity of oxaliplatin through DeltaNP73 negative regulation in colon cancer, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(19), 4398-4409. doi:10.1158/1078-0432.CCR-14-2027 [doi]
Jansen, M. H., Lagerweij, T., Sewing, A. C., Vugts, D. J., van Vuurden, D. G., Molthoff, C. F., . . . Hulleman, E. (2016).,
Bevacizumab targeting diffuse intrinsic pontine glioma: Results of 89Zr-bevacizumab PET imaging in brain tumor models., Molecular Cancer Therapeutics, 15(9), 2166-2174. doi:10.1158/1535-7163.MCT-15-0558 [doi]
Zhang, Y., Chen, X., Qiao, M., Zhang, B. Q., Wang, N., Zhang, Z., . . . Zhang, H. (2014).,
Bone morphogenetic protein 2 inhibits the proliferation and growth of human colorectal cancer cells., Oncology Reports, 32(3), 1013-1020. doi:10.3892/or.2014.3308 [doi]
Bort, A., Spinola, E., Rodriguez-Henche, N., & Diaz-Laviada, I. (2017).,
Capsaicin exerts synergistic antitumor effect with sorafenib in hepatocellular carcinoma cells through AMPK activation, Oncotarget, 8(50), 87684-87698. doi:10.18632/oncotarget.21196 [doi]
Kim, H. S., Masko, E. M., Poulton, S. L., Kennedy, K. M., Pizzo, S. V., Dewhirst, M. W., & Freedland, S. J. (2012).,
Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer., BJU International, 110(7), 1062-1069. doi:10.1111/j.1464-410X.2012.10971.x [doi]
Li, H., Xie, N., Gleave, M. E., & Dong, X. (2015,
Catalytic inhibitors of DNA topoisomerase II suppress the androgen receptor signaling and prostate cancer progression., Oncotarget, 6(24), 20474-20484. doi:4105 [pii]
Assimon, Victoria A; Tang, Yangzhong; Vargas, Jesse D; Lee, Grace J; Wu, Zhi Yong; Lou, Kenny; Yao, Bing; Menon, Mary-Kamala; Pios, Ariel; Perez, Kristy C; Madriaga, Antonett; Buchowiecki, Peter K; Rolfe, Mark; Shawver, Laura; Jiao, Xianyun; Le Moigne, Ronan; Zhou, Han-Jie; Anderson, Daniel J;,
CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity. ACS chemical biology, ACS chemical biology Vol.14, 2019
Domínguez JM, Pérez-Chacón G, Guillén MJ, Muñoz-Alonso MJ, Somovilla-Crespo B, Cibrián D, Acosta-Iborra B, Adrados M, Muñoz-Calleja C, Cuevas C, Sánchez-Madrid F, Avilés P, Zapata JM.,
CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110, J Hematol Oncol. 2020 Apr 7;13(1):32. doi: 10.1186/s13045-020-00865-7.
Hernandez, R., Sun, H., England, C. G., Valdovinos, H. F., Ehlerding, E. B., Barnhart, T. E., . . . Cai, W. (2016),
CD146-targeted immunoPET and NIRF imaging of hepatocellular carcinoma with a dual-labeled monoclonal antibody., Theranostics, 6(11), 1918-1933. doi:10.7150/thno.15568 [doi]
Smith, M. C., Mader, M. M., Cook, J. A., Iversen, P., Ajamie, R., Perkins, E., . . . Wacheck, V. (2016).,
Characterization of LY3023414, a novel PI3K/mTOR dual inhibitor eliciting transient target modulation to impede tumor growth., Molecular Cancer Therapeutics, 15(10), 2344-2356. doi:1535-7163.MCT-15-0996 [pii]
Weitzenfeld, P., Kossover, O., Korner, C., Meshel, T., Wiemann, S., Seliktar, D., . . . Ben-Baruch, A. (2016).,
Chemokine axes in breast cancer: Factors of the tumor microenvironment reshape the CCR7-driven metastatic spread of luminal-A breast tumors., Journal of Leukocyte Biology, 99(6), 1009-1025. doi:10.1189/jlb.3MA0815-373R [doi]
Sen, T., Tong, P., Stewart, C. A., Cristea, S., Valliani, A., Shames, D. S., . . . Byers, L. A. (2017).,
CHK1 inhibition in small-cell lung cancer produces single-agent activity in biomarker-defined disease subsets and combination activity with cisplatin or olaparib., Cancer Research, 77(14), 3870-3884. doi:10.1158/0008-5472.CAN-16-3409 [doi]
Li, J., Qu, X., Tian, J., Zhang, J. T., & Cheng, J. X. (2018).,
Cholesterol esterification inhibition and gemcitabine synergistically suppress pancreatic ductal adenocarcinoma proliferation., PloS One, 13(2), e0193318. doi:10.1371/journal.pone.0193318 [doi]
Sobot, D., Mura, S., Rouquette, M., Vukosavljevic, B., Cayre, F., Buchy, E., . . . Couvreur, P. (2017).,
Circulating lipoproteins: A trojan horse guiding squalenoylated drugs to LDL-accumulating cancer cells., Molecular Therapy : The Journal of the American Society of Gene Therapy, 25(7), 1596-1605. doi:S1525-0016(17)30234-4 [pii]
Yu, W., Chen, Y., Dubrulle, J., Stossi, F., Putluri, V., Sreekumar, A., . . . Sandulache, V. C. (2018).,
Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism, Scientific Reports, 8(1), 4306-018-22640-y. doi:10.1038/s41598-018-22640-y [doi]
Parsels LA, Engelke CG, Parsels J, Flanagan SA, Zhang Q, Tanska D, Wahl DR, Canman CE, Lawrence TS, Morgan MA.,
Combinatorial efficacy of olaparib with radiation and ATR inhibitor requires PARP1 protein in homologous recombination proficient pancreatic cancer, Mol Cancer Ther. 2020 Dec 2:molcanther.0365.2020. doi: 10.1158/1535-7163.MCT-20-0365. Online ahead of print.
Belli, Valentina; Matrone, Nunzia; Napolitano, Stefania; Migliardi, Giorgia; Cottino, Francesca; Bertotti, Andrea; Trusolino, Livio; Martinelli, Erika; Morgillo, Floriana; Ciardiello, Davide; De Falco, Vincenzo; Giunta, Emilio Francesco; Bracale, Umberto; Ciardiello, Fortunato; Troiani, Teresa;,
Combined blockade of MEK and PI3KCA as an effective antitumor strategy in HER2 gene amplified human colorectal cancer models., Journal of experimental & clinical cancer research : CR Vol.38, 2019
Frost, S. H., Frayo, S. L., Miller, B. W., Orozco, J. J., Booth, G. C., Hylarides, M. D., . . . Press, O. W. (2015),
Comparative efficacy of 177Lu and 90Y for anti-CD20 pretargeted radioimmunotherapy in murine lymphoma xenograft models., PloS One, 10(3), e0120561. doi:10.1371/journal.pone.0120561 [doi]
Vugts, D. J., Klaver, C., Sewing, C., Poot, A. J., Adamzek, K., Huegli, S., . . . van Dongen, G. A. (2017).,
Comparison of the octadentate bifunctional chelator DFO*-pPhe-NCS and the clinically used hexadentate bifunctional chelator DFO-pPhe-NCS for (89)zr-immuno-PET., European Journal of Nuclear Medicine and Molecular Imaging, 44(2), 286-295. doi:10.1007/s00259-016-3499-x [doi]
Pattarawat P, Hong T, Wallace S, Hu Y, Donnell R, Wang TH, Tsai CL, Wang J, Wang HR.,
Compensatory combination of romidepsin with gemcitabine and cisplatin to effectively and safely control urothelial carcinoma, Br J Cancer. 2020 Jul;123(2):226-239. doi: 10.1038/s41416-020-0877-8. Epub 2020 May 11.
Shibata M, Ooki A, Inokawa Y, Sadhukhan P, Ugurlu MT, Izumchenko E, Munari E, Bogina G, Rudin CM, Gabrielson E, Singh A, Hoque MO.,
Concurrent Targeting of Potential Cancer Stem Cells Regulating Pathways Sensitizes Lung Adenocarcinoma to Standard Chemotherapy, Mol Cancer Ther. 2020 Oct;19(10):2175-2185. doi: 10.1158/1535-7163.MCT-20-0024. Epub 2020 Aug 26.
刘,彭;赵,身子;乔纳森·波尔;几何,年代arah; Petrazzuolo, Adriana; Pfirschke, Christina; Engblom, Camilla; Rickelt, Steffen; Yamazaki, Takahiro; Iribarren, Kristina; Senovilla, Laura; Bezu, Lucillia; Vacchelli, Erika; Sica, Valentina; Melis, Andréa; Martin, Tiffany; Xia, Lin; Yang, Heng; Li, Qingqing; Chen, Jinfeng; Durand, Sylvère; Aprahamian, Fanny; Lefevre, Deborah; Broutin, Sophie; Paci, Angelo; Bongers, Amaury; Minard-Colin, Veronique; Tartour, Eric; Zitvogel, Laurence; Apetoh, Lionel; Ma, Yuting; Pittet, Mikael J; Kepp, Oliver; Kroemer, Guido;,
Crizotinib-induced immunogenic cell death in non-small cell lung cancer, Nature communications Vol.10, 2019
Yamaguchi, M., Zhu, S., Zhang, S., Wu, D., Moore, T. M., Snyder, J. P., & Shoji, M. (2014).,
Curcumin analogue UBS109 prevents bone loss in breast cancer bone metastasis mouse model: Involvement in osteoblastogenesis and osteoclastogenesis, Cell and Tissue Research, 357(1), 245-252. doi:10.1007/s00441-014-1846-4 [doi]
Domanska, U. M., Boer, J. C., Timmer-Bosscha, H., van Vugt, M. A., Hoving, H. D., Kliphuis, N. M., . . . Walenkamp, A. M. (2014).,
CXCR4 inhibition enhances radiosensitivity, while inducing cancer cell mobilization in a prostate cancer mouse model临床和实验转移,31 (7),829 - 839. doi:10.1007/s10585-014-9673-2 [doi]
Garcia, M., Velez, R., Romagosa, C., Majem, B., Pedrola, N., Olivan, M., . . . Doll, A. (2014).,
Cyclooxygenase-2 inhibitor suppresses tumour progression of prostate cancer bone metastases in nude mice, BJU International, 113(5b), E164-77. doi:10.1111/bju.12503 [doi]
Perez, O. D., Logg, C. R., Hiraoka, K., Diago, O., Burnett, R., Inagaki, A., . . . Jolly, D. J. (2012).,
Design and selection of toca 511 for clinical use: Modified retroviral replicating vector with improved stability and gene expression, Molecular Therapy : The Journal of the American Society of Gene Therapy, 20(9), 1689-1698. doi:10.1038/mt.2012.83 [doi]
D'Hollander, A., Mathieu, E., Jans, H., Vande Velde, G., Stakenborg, T., Van Dorpe, P., . . . Lagae, L. (2016),
Development of nanostars as a biocompatible tumor contrast agent: Toward in vivo SERS imaging., International Journal of Nanomedicine, 11, 3703-3714. doi:10.2147/IJN.S91340 [doi]
Navarro-Villaran, E., Tinoco, J., Jimenez, G., Pereira, S., Wang, J., Aliseda, S., . . . Muntane, J. (2016).,
微分antitumoral属性和renal-associated tissue damage induced by tacrolimus and mammalian target of rapamycin inhibitors in hepatocarcinoma: In vitro and in vivo studies, PloS One, 11(8), e0160979. doi:10.1371/journal.pone.0160979 [doi]
Oksala, R., Moilanen, A., Riikonen, R., Rummakko, P., Karjalainen, A., Passiniemi, M., . . . Mustonen, M. V. (2018),
Discovery and development of ODM-204: A novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1, The Journal of Steroid Biochemistry and Molecular Biology, doi:S0960-0760(18)30078-5 [pii]
Hiriyan, J., Shivarudraiah, P., Gavara, G., Annamalai, P., Natesan, S., Sambasivam, G., & Sukumaran, S. K. (2015).,
Discovery of PAT-1102, a novel, potent and orally active histone deacetylase inhibitor with antitumor activity in cancer mouse models. Anticancer, Anticancer Research, 35(1), 229-237. doi:35/1/229 [pii]
Donabedian, P. L., Kossatz, S., Engelbach, J. A., Jannetti, S. A., Carney, B., Young, R. J., . . . Reiner, T. (2018).,
Discriminating radiation injury from recurrent tumor with [(18)F]PARPi and amino acid PET in mouse models., EJNMMI Research, 8(1), 59-018-0399-z. doi:10.1186/s13550-018-0399-z [doi]
Tuomela, J., Sandholm, J., Kaakinen, M., Patel, A., Kauppila, J. H., Ilvesaro, J., . . . Selander, K. S. (2013).,
DNA from dead cancer cells induces TLR9-mediated invasion and inflammation in living cancer cells., Breast Cancer Research and Treatment, 142(3), 477-487. doi:10.1007/s10549-013-2762-0 [doi]
Sciegienka, S. J., Solst, S. R., Falls, K. C., Schoenfeld, J. D., Klinger, A. R., Ross, N. L., . . . Fath, M. A. (2017).,
D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H2O2-mediated oxidative stress., Free Radical Biology & Medicine, 108, 354-361. doi:S0891-5849(17)30192-2 [pii]
Tsoneva, D., Stritzker, J., Bedenk, K., Zhang, Q., Frentzen, A., Cappello, J., . . . Szalay, A. A. (2015).,
Drug-encoded biomarkers for monitoring biological therapies, PloS One, 10(9), e0137573. doi:10.1371/journal.pone.0137573 [doi]
Ohana, J., Sandler, U., Kass, G., Stemmer, S. M., & Devary, Y. (2017).,
dTCApFs, a derivative of a novel human hormone peptide, induces apoptosis in cancer cells through a mechanism involving loss of golgi function., Molecular and Clinical Oncology, 7(6), 991-999. doi:10.3892/mco.2017.1453 [doi]
Luo, H., England, C. G., Shi, S., Graves, S. A., Hernandez, R., Liu, B., . . . Cai, W. (2016).,
Dual targeting of tissue factor and CD105 for preclinical PET imaging of pancreatic cancer., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(15), 3821-3830. doi:10.1158/1078-0432.CCR-15-2054 [doi]
Tan, Q., Joshua, A. M., Saggar, J. K., Yu, M., Wang, M., Kanga, N., . . . Tannock, I. F. (2015),
Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy., British Journal of Cancer, 112(5), 832-840. doi:10.1038/bjc.2015.17 [doi]
Ionkina, A. A., Tentler, J. J., Kim, J., Capasso, A., Pitts, T. M., Ryall, K. A., . . . Diamond, J. R. (2017).,
Efficacy and molecular mechanisms of differentiated response to the aurora and angiogenic kinase inhibitor ENMD-2076 in preclinical models of p53-mutated triple-negative breast cancer., Frontiers in Oncology, 7, 94. doi:10.3389/fonc.2017.00094 [doi]
Kong, Y., Barisone, G. A., Sidhu, R. S., O'Donnell, R. T., & Tuscano, J. M. (2015).,
Efficacy of combined histone deacetylase and checkpoint kinase inhibition in a preclinical model of human burkitt lymphoma., Molecular Medicine (Cambridge, Mass.), 21(1), 824-832. doi:10.2119/molmed.2015.00032 [doi]
Akla, Barbara; Broussas, Matthieu; Loukili, Noureddine; Robert, Alain; Beau-Larvor, Charlotte; Malissard, Martine; Boute, Nicolas; Champion, Thierry; Haeuw, Jean-Francois; Beck, Alain; Perez, Michel; Dreyfus, Cyrille; Pavlyuk, Mariya; Chetaille, Eric; Corvaia, Nathalie;,
Efficacy of the Antibody-Drug Conjugate W0101 in Preclinical Models of IGF-1 Receptor Overexpressing Solid Tumors., Molecular cancer therapeutics Vol.19, 2020
Choi, A. H., O'Leary, M. P., Lu, J., Kim, S. I., Fong, Y., & Chen, N. G. (2018),
Endogenous akt activity promotes virus entry and predicts efficacy of novel chimeric orthopoxvirus in triple-negative breast cancer., Molecular Therapy Oncolytics, 9, 22-29. doi:10.1016/j.omto.2018.04.001 [doi]
Toden, S., Tran, H. M., Tovar-Camargo, O. A., Okugawa, Y., & Goel, A. (2016),
Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer., Oncotarget, 7(13), 16158-16171. doi:10.18632/oncotarget.7567 [doi]
Wang, X., Tan, Y., Cao, X., Kim, J. A., Chen, T., Hu, Y., . . . Wang, X. (2018).,
Epigenetic activation of HORMAD1 in basal-like breast cancer: Role in rucaparib sensitivity., Oncotarget, 9(53), 30115-30127. doi:10.18632/oncotarget.25728 [doi]
Schmitt, D. C., Madeira da Silva, L., Zhang, W., Liu, Z., Arora, R., Lim, S., . . . Tan, M. (2015).,
ErbB2-intronic microRNA-4728: A novel tumor suppressor and antagonist of oncogenic MAPK signaling., Cell Death & Disease, 6, e1742. doi:10.1038/cddis.2015.116 [doi]
Bhagwat SV, McMillen WT, Cai S, Zhao B, Whitesell M, Shen W, Kindler L, Flack RS, Wu W, Anderson B, Zhai Y, Yuan XJ, Pogue M, Van Horn RD, Rao X, McCann D, Dropsey AJ, Manro J, Walgren J, Yuen E, Rodriguez MJ, Plowman GD, Tiu RV, Joseph S, Peng SB.,
ERK Inhibitor LY3214996 Targets ERK Pathway-Driven Cancers: A Therapeutic Approach Toward Precision Medicine, Mol Cancer Ther. 2020 Feb;19(2):325-336. doi: 10.1158/1535-7163.MCT-19-0183. Epub 2019 Nov 19.
Maaland, Astri Fjelde; Heyerdahl, Helen; OShea, Adam; Eiriksdottir, Bergthora; Pascal, Véronique; Andersen, Jan Terje; Kolstad, Arne; Dahle, Jostein;,
European journal of nuclear medicine and molecular imaging Vol.46, 2019, European journal of nuclear medicine and molecular imaging Vol.46, 2019
Tuominen S, Keller T, Petruk N, López-Picón F, Eichin D, Löyttyniemi E, Verhassel A, Rajander J, Sandholm J, Tuomela J, Grönroos TJ.,
Evaluation of [(18)F]F-DPA as a target for TSPO in head and neck cancer under normal conditions and after radiotherapy, Eur J Nucl Med Mol Imaging. 2020 Dec 19. doi: 10.1007/s00259-020-05115-z. Online ahead of print.
Scott, A. J., Song, E. K., Bagby, S., Purkey, A., McCarter, M., Gajdos, C., . . . Messersmith, W. A. (2017).,
Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model., PloS One, 12(11), e0187173. doi:10.1371/journal.pone.0187173 [doi]
Siddiqui, I. A., Bharali, D. J., Nihal, M., Adhami, V. M., Khan, N., Chamcheu, J. C., . . . Mukhtar, H. (2014).,
Excellent anti-proliferative and pro-apoptotic effects of (-)-epigallocatechin-3-gallate encapsulated in chitosan nanoparticles on human melanoma cell growth both in vitro and in vivo., Nanomedicine : Nanotechnology, Biology, and Medicine, 10(8), 1619-1626. doi:10.1016/j.nano.2014.05.007 [doi]
Gonzalez-Sanchez L, Cobos-Fernandez MA, Lopez-Nieva P, Villa-Morales M, Stamatakis K, Cuezva JM, Marin-Rubio JL, Vazquez-Dominguez I, Gonzalez-Vasconcellos I, Salido E, Llamas P, Lopez-Lorenzo JL, Santos J, Fernandez-Piqueras J.,
Exploiting the passenger ACO1-deficiency arising from 9p21 deletions to kill T-cell lymphoblastic neoplasia cells, Carcinogenesis. 2020 Aug 12;41(8):1113-1122. doi: 10.1093/carcin/bgz185.
Capasso, Anna; Bagby, Stacey M; Dailey, Kyrie L; Currimjee, Naomi; Yacob, Betelehem W; Ionkina, Anastasia; Frank, Julie G; Kim, Deog Joong; George, Christina; Lee, Young B; Benaim, Ely; Gittleman, Brian; Hartman, Sarah J; Tan, Aik Choon; Kim, Jihye; Pitts, Todd M; Eckhardt, S Gail; Tentler, John J; Diamond, Jennifer R;,
First-in-Class Phosphorylated-p68抑制剂rx - 5902 Inhibits ??-Catenin Signaling and Demonstrates Antitumor Activity in Triple-Negative Breast Cancer, Molecular cancer therapeutics Vol.18, 2019
Faugeroux V, Pailler E, Oulhen M, Deas O, Brulle-Soumare L, Hervieu C, Marty V, Alexandrova K, Andree KC, Stoecklein NH, Tramalloni D, Cairo S, NgoCamus M, Nicotra C, Terstappen LWMM, Manaresi N, Lapierre V, Fizazi K, Scoazec JY, Loriot Y, Judde JG, Farace F.,
Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model, Nat Commun. 2020 Apr 20;11(1):1884. doi: 10.1038/s41467-020-15426-2.
Sasaki, K., Kurahara, H., Young, E. D., Natsugoe, S., Ijichi, A., Iwakuma, T., & Welch, D. R. (2017).,
Genome-wide in vivo RNAi screen identifies ITIH5 as a metastasis suppressor in pancreatic cancer., Clinical & Experimental Metastasis, 34(3-4), 229-239. doi:10.1007/s10585-017-9840-3 [doi]
Lampa, M., Arlt, H., He, T., Ospina, B., Reeves, J., Zhang, B., . . . Srinivasan, L. (2017).,
Glutaminase is essential for the growth of triple-negative breast cancer cells with a deregulated glutamine metabolism pathway and its suppression synergizes with mTOR inhibition, PloS One, 12(9), e0185092. doi:10.1371/journal.pone.0185092 [doi]
Sorin, V., Ohana, P., Gallula, J., Birman, T., Matouk, I., Hubert, A., . . . Czerniak, A. (2012).,
H19-promoter-targeted therapy combined with gemcitabine in the treatment of pancreatic cancer, ISRN Oncology, 2012, 351750. doi:10.5402/2012/351750 [doi]
Zhou, Y., Li, G., Zhu, L., Li, C., Cornelius, L. A., & Wang, L. V. (2015).,
Handheld photoacoustic probe to detect both melanoma depth and volume at high speed in vivo., Journal of Biophotonics, 8(11-12), 961-967. doi:10.1002/jbio.201400143 [doi]
Arzumanyan, A., Sambandam, V., Clayton, M. M., Choi, S. S., Xie, G., Diehl, A. M., . . . Feitelson, M. A. (2012).,
Hedgehog signaling blockade delays hepatocarcinogenesis induced by hepatitis B virus X protein., Cancer Research, 72(22), 5912-5920. doi:10.1158/0008-5472.CAN-12-2329 [doi]
Elwaie TA, Abbas SE, Aly EI, George RF, Ali H, Kraiouchkine N, Abdelwahed KS, Fandy TE, El Sayed KA, Abd Elmageed ZY, Ali HI.,
HER2 Kinase-Targeted Breast Cancer Therapy: Design, Synthesis, and In Vitro and In Vivo Evaluation of Novel Lapatinib Congeners as Selective and Potent HER2 Inhibitors with Favorable Metabolic Stability, J Med Chem. 2020 Dec 24;63(24):15906-15945. doi: 10.1021/acs.jmedchem.0c01647. Epub 2020 Dec 14.
Efimova, E. V., Ricco, N., Labay, E., Mauceri, H. J., Flor, A. C., Ramamurthy, A., . . . Kron, S. J. (2018).,
HMG-CoA reductase inhibition delays DNA repair and promotes senescence after tumor irradiation., Molecular Cancer Therapeutics, 17(2), 407-418. doi:10.1158/1535-7163.MCT-17-0288 [doi]
Lelj-Garolla, B., Kumano, M., Beraldi, E., Nappi, L., Rocchi, P., Ionescu, D. N., . . . Gleave, M. E. (2015).,
Hsp27 inhibition with OGX-427 sensitizes non-small cell lung cancer cells to erlotinib and chemotherapy., Molecular Cancer Therapeutics, 14(5), 1107-1116. doi:10.1158/1535-7163.MCT-14-0866 [doi]
Lu, Y., Liu, Y., Oeck, S., & Glazer, P. M. (2018).,
Hypoxia promotes resistance to EGFR inhibition in NSCLC cells via the histone demethylases, LSD1 and PLU-1., Molecular Cancer Research : MCR, 16(10), 1458-1469. doi:10.1158/1541-7786.MCR-17-0637 [doi]
Lu, Y., Liu, Y., Oeck, S., & Glazer, P. M. (2018).,
Hypoxia promotes resistance to EGFR inhibition in NSCLC cells via the histone demethylases, LSD1 and PLU-1., Molecular Cancer Research : MCR, 16(10), 1458-1469. doi:10.1158/1541-7786.MCR-17-0637 [doi]
Fell JB, Fischer JP, Baer BR, Blake JF, Bouhana K, Briere DM, Brown KD, Burgess LE, Burns AC, Burkard MR, Chiang H, Chicarelli MJ, Cook AW, Gaudino JJ, Hallin J, Hanson L, Hartley DP, Hicken EJ, Hingorani GP, Hinklin RJ, Mejia MJ, Olson P, Otten JN, Rhodes SP, Rodriguez ME, Savechenkov P, Smith DJ, Sudhakar N, Sullivan FX, Tang TP, Vigers GP, Wollenberg L, Christensen JG, Marx MA.,
Identification of the Clinical Development Candidate MRTX849, a Covalent KRAS(G12C) Inhibitor for the Treatment of Cancer, J Med Chem. 2020 Jul 9;63(13):6679-6693. doi: 10.1021/acs.jmedchem.9b02052. Epub 2020 Apr 6.
Abourbeh, G., Itamar, B., Salnikov, O., Beltsov, S., & Mishani, E. (2015).,
Identifying erlotinib-sensitive non-small cell lung carcinoma tumors in mice using [(11)C]erlotinib PET., EJNMMI Research, 5, 4-014-0080-0. eCollection 2015. doi:10.1186/s13550-014-0080-0 [doi]
Attaluri, A., Seshadri, M., Mirpour, S., Wabler, M., Marinho, T., Furqan, M., . . . Liapi, E. (2016),
Image-guided thermal therapy with a dual-contrast magnetic nanoparticle formulation: A feasibility study. International Journal of Hyperthermia, The Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group, 32(5), 543-557. doi:10.3109/02656736.2016.1159737 [doi]
Brignole, C., Pastorino, F., Marimpietri, D., Pagnan, G., Pistorio, A., Allen, T. M., . . . Ponzoni, M. (2004).,
Immune cell-mediated antitumor activities of GD2-targeted liposomal c-myb antisense oligonucleotides containing CpG motifs., Journal of the National Cancer Institute, 96(15), 1171-1180. doi:10.1093/jnci/djh221 [doi]
Sun, H., England, C. G., Hernandez, R., Graves, S. A., Majewski, R. L., Kamkaew, A., . . . Cai, W. (2016).,
ImmunoPET for assessing the differential uptake of a CD146-specific monoclonal antibody in lung cancer, European Journal of Nuclear Medicine and Molecular Imaging, 43(12), 2169-2179. doi:10.1007/s00259-016-3442-1 [doi]
埃尔南德斯,R,英格兰,c·G。杨,Y。,Valdovinos, H. F., Liu, B., Wong, H. C., . . . Cai, W. (2017).,
ImmunoPET imaging of tissue factor expression in pancreatic cancer with (89)zr-df-ALT-836, Journal of Controlled Release : Official Journal of the Controlled Release Society, 264, 160-168. doi:S0168-3659(17)30796-4 [pii]
Guffanti F, Alvisi MF, Caiola E, Ricci F, De Maglie M, Soldati S, Ganzinelli M, Decio A, Giavazzi R, Rulli E, Damia G.,
Impact of ERCC1, XPF and DNA Polymerase ? Expression on Platinum Response in Patient-Derived Ovarian Cancer Xenografts, Cancers (Basel). 2020 Aug 24;12(9):2398. doi: 10.3390/cancers12092398.
Heinrich, A. K., Lucas, H., Schindler, L., Chytil, P., Etrych, T., Mader, K., & Mueller, T. (2016),
Improved tumor-specific drug accumulation by polymer therapeutics with pH-sensitive drug release overcomes chemotherapy resistance, Molecular Cancer Therapeutics, 15(5), 998-1007. doi:10.1158/1535-7163.MCT-15-0824 [doi]
Hughes, P. E., Rex, K., Caenepeel, S., Yang, Y., Zhang, Y., Broome, M. A., . . . Coxon, A. (2016).,
337年AMG体外和体内活动,有力and selective MET kinase inhibitor, in MET-dependent cancer models., Molecular Cancer Therapeutics, 15(7), 1568-1579. doi:10.1158/1535-7163.MCT-15-0871 [doi]
Xia, C. F., Chen, G., Gangadharmath, U., Gomez, L. F., Liang, Q., Mu, F., . . . Kolb, H. C. (2013),
In vitro and in vivo evaluation of the caspase-3 substrate-based radiotracer [(18)F]-CP18 for PET imaging of apoptosis in tumors., Molecular Imaging and Biology : MIB : The Official Publication of the Academy of Molecular Imaging, 15(6), 748-757. doi:10.1007/s11307-013-0646-7 [doi]
He, Y., Wang, L., Shi, J., Yao, J., Li, L., Zhang, R., . . . Wang, L. V. (2016),
In vivo label-free photoacoustic flow cytography and on-the-spot laser killing of single circulating melanoma cells, Scientific Reports, 6, 39616. doi:10.1038/srep39616 [doi]
Rybczynska, A. A., de Bruyn, M., Ramakrishnan, N. K., de Jong, J. R., Elsinga, P. H., Helfrich, W., . . . van Waarde, A. (2013).,
In vivo responses of human A375M melanoma to a sigma ligand: 18F-FDG PET imaging., Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 54(9), 1613-1620. doi:10.2967/jnumed.113.122655 [doi]
Colmegna, B., Uboldi, S., Frapolli, R., Licandro, S. A., Panini, N., Galmarini, C. M., . . . D'Incalci, M. (2015),
Increased sensitivity to platinum drugs of cancer cells with acquired resistance to trabectedin., British Journal of Cancer, 113(12), 1687-1693. doi:10.1038/bjc.2015.407 [doi]
Gunsalus, K. T., Wagoner, M. P., Meyer, K., Potter, W. B., Schoenike, B., Kim, S., . . . Roopra, A. (2012).,
Induction of the RNA regulator LIN28A is required for the growth and pathogenesis of RESTless breast tumors, Cancer Research, 72(13), 3207-3216. doi:10.1158/0008-5472.CAN-11-1639 [doi]
Wang, X., Solban, N., Khanna, P., Callea, M., Song, J., Alsop, D. C., . . . Bhatt, R. S. (2016).,
Inhibition of ALK1 signaling with dalantercept combined with VEGFR TKI leads to tumor stasis in renal cell carcinoma., Oncotarget, 7(27), 41857-41869. doi:10.18632/oncotarget.9621 [doi]
Cook Sangar, M. L., Genovesi, L. A., Nakamoto, M. W., Davis, M. J., Knobluagh, S. E., Ji, P., . . . Olson, J. M. (2017).,
Inhibition of CDK4/6 by palbociclib significantly extends survival in medulloblastoma patient-derived xenograft mouse models., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(19), 5802-5813. doi:10.1158/1078-0432.CCR-16-2943 [doi]
Zhang, Y., Wang, Q., Chen, L., & Yang, H. S. (2015),
Inhibition of p70S6K1 activation by Pdcd4 overcomes the resistance to an IGF-1R/IR inhibitor in colon carcinoma cells., Molecular Cancer Therapeutics, 14(3), 799-809. doi:10.1158/1535-7163.MCT-14-0648 [doi]
Shao, C., Ahmad, N., Hodges, K., Kuang, S., Ratliff, T., & Liu, X. (2015).,
Inhibition of polo-like kinase 1 (Plk1) enhances the antineoplastic activity of metformin in prostate cancer., The Journal of Biological Chemistry, 290(4), 2024-2033. doi:10.1074/jbc.M114.596817 [doi]
Gómez-Aleza C, Nguyen B, Yoldi G, Ciscar M, Barranco A, Hernández-Jiménez E, Maetens M, Salgado R, Zafeiroglou M, Pellegrini P, Venet D, Garaud S, Trinidad EM, Benítez S, Vuylsteke P, Polastro L, Wildiers H, Simon P, Lindeman G, Larsimont D, Van den Eynden G, Velghe C, Rothé F, Willard-Gallo K, Michiels S, Muñoz P, Walzer T, Planelles L, Penninger J, Azim HA Jr, Loi S, Piccart M, Sotiriou C, González-Suárez E.,
Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells, Nat Commun. 2020 Dec 10;11(1):6335. doi: 10.1038/s41467-020-20138-8.
Humeau J, Sauvat A, Cerrato G, Xie W, Loos F, Iannantuoni F, Bezu L, Lévesque S, Paillet J, Pol J, Leduc M, Zitvogel L, de Thé H, Kepp O, Kroemer G.,
Inhibition of transcription by dactinomycin reveals a new characteristic of immunogenic cell stress, EMBO Mol Med. 2020 May 8;12(5):e11622. doi: 10.15252/emmm.201911622. Epub 2020 Apr 23.
Puente, P., Fettig, N., Luderer, M. J., Jin, A., Shah, S., Muz, B., . . . Azab, A. K. (2018).,
Injectable hydrogels for localized chemotherapy and radiotherapy in brain tumors., Journal of Pharmaceutical Sciences, 107(3), 922-933. doi:S0022-3549(17)30829-8 [pii]
Wu, Jiao; Minikes, Alexander M; Gao, Minghui; Bian, Huijie; Li, Yong; Stockwell, Brent R; Chen, Zhi-Nan; Jiang, Xuejun;,
Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling, Nature Vol.572, 2019
Wang, W., Cho, H. Y., Rosenstein-Sisson, R., Marin Ramos, N. I., Price, R., Hurth, K., . . . Chen, T. C. (2018),
Intratumoral delivery of bortezomib: Impact on survival in an intracranial glioma tumor model, Journal of Neurosurgery, 128(3), 695-700. doi:10.3171/2016.11.JNS161212 [doi]
Relation, T., Yi, T., Guess, A. J., La Perle, K., Otsuru, S., Hasgur, S., . . . Horwitz, E. M. (2018).,
Intratumoral delivery of interferongamma-secreting mesenchymal stromal cells repolarizes tumor-associated macrophages and suppresses neuroblastoma proliferation in vivo., Stem Cells (Dayton, Ohio), 36(6), 915-924. doi:10.1002/stem.2801 [doi]
Turchan, W. T., Shapiro, R. H., Sevigny, G. V., Chin-Sinex, H., Pruden, B., & Mendonca, M. S. (2016).,
Irradiated human endothelial progenitor cells induce bystander killing in human non-small cell lung and pancreatic cancer cells, International Journal of Radiation Biology, 92(8), 427-433. doi:10.1080/09553002.2016.1186299 [doi]
Wu Q, Tian AL, Durand S, Aprahamian F, Nirmalathasan N, Xie W, Liu P, Zhao L, Zhang S, Pan H, Carmona-Gutierrez D, Madeo F, Tu Y, Kepp O, Kroemer G.,
Isobacachalcone induces autophagy and improves the outcome of immunogenic chemotherapy, Cell Death Dis. 2020 Nov 26;11(11):1015. doi: 10.1038/s41419-020-03226-x.
Gelsomino L, Naimo GD, Malivindi R, Augimeri G, Panza S, Giordano C, Barone I, Bonofiglio D, Mauro L, Catalano S, Andò S.,
Knockdown of Leptin Receptor Affects Macrophage Phenotype in the Tumor Microenvironment Inhibiting Breast Cancer Growth and Progression, Cancers (Basel). 2020 Jul 27;12(8):2078. doi: 10.3390/cancers12082078.
Dwivedi SKD, Shameer K, Dey A, Mustafi SB, Xiong X, Bhattacharya U, Neizer-Ashun F, Rao G, Wang Y, Ivan C, Yang D, Dudley JT, Xu C, Wren JD, Mukherjee P, Bhattacharya R.,
KRCC1: A potential therapeutic target in ovarian cancer, FASEB J. 2020 Feb;34(2):2287-2300. doi: 10.1096/fj.201902259R. Epub 2019 Dec 23.
Haedicke, K., Graefe, S., Teichgraeber, U., & Hilger, I. (2016).,
Lowering photosensitizer doses and increasing fluences induce apoptosis in tumor bearing mice, Biomedical Optics Express, 7(7), 2641-2649. doi:10.1364/BOE.7.002641 [doi]
Santamaria Nunez, G., Robles, C. M., Giraudon, C., Martinez-Leal, J. F., Compe, E., Coin, F., . . . Egly, J. M. (2016).,
Lurbinectedin specifically triggers the degradation of phosphorylated RNA polymerase II and the formation of DNA breaks in cancer cells., Molecular Cancer Therapeutics, 15(10), 2399-2412. doi:1535-7163.MCT-16-0172 [pii]
Johnson, J. L., Dia, V. P., Wallig, M., & Gonzalez de Mejia, E. (2015),
Luteolin and gemcitabine protect against pancreatic cancer in an orthotopic mouse model., Pancreas, 44(1), 144-151. doi:10.1097/MPA.0000000000000215 [doi]
Roger E, Gout J, Arnold F, Beutel AK, Müller M, Abaei A, Barth TFE, Rasche V, Seufferlein T, Perkhofer L, Kleger A.,
Maintenance Therapy for ATM-Deficient Pancreatic Cancer by Multiple DNA Damage Response Interferences after Platinum-Based Chemotherapy, Cells. 2020 Sep 16;9(9):2110. doi: 10.3390/cells9092110.
Bernardo, M. M., Kaplun, A., Dzinic, S. H., Li, X., Irish, J., Mujagic, A., . . . Sheng, S. (2015),
Maspin expression in prostate tumor cells averts stemness and stratifies drug sensitivity, Cancer Research, 75(18), 3970-3979. doi:10.1158/0008-5472.CAN-15-0234 [doi]
Franklin DA, Sharick JT, Ericsson-Gonzalez PI, Sanchez V, Dean PT, Opalenik SR, Cairo S, Judde JG, Lewis MT, Chang JC, Sanders ME, Cook RS, Skala MC, Bordeaux J, Orozco Bender J, Vaupel C, Geiss G, Hinerfeld D, Balko JM.,
MEK activation modulates glycolysis and supports suppressive myeloid cells in TNBC, JCI Insight. 2020 Aug 6;5(15):e134290. doi: 10.1172/jci.insight.134290.
García-García, Celina; Rivas, Martín A; Ibrahim, Yasir H; Calvo, María Teresa; Gris-Oliver, Albert; Rodríguez, Olga; Grueso, Judit; Antón, Pilar; Guzmán, Marta; Aura, Claudia; Nuciforo, Paolo; Jessen, Katti; Argilés, Guillem; Dienstmann, Rodrigo; Bertotti, Andrea; Trusolino, Livio; Matito, Judit; Vivancos, Ana; Chicote, Irene; Palmer, Héctor G; Tabernero, Josep; Scaltriti, Maurizio; Baselga, José; Serra, Violeta,
MEK plus PI3K/mTORC1/2 Therapeutic Efficacy Is Impacted by TP53 Mutation in Preclinical Models of Colorectal Cancer., Clinical cancer research : an official journal of the American Association for Cancer Research Vol.21, 2015
Sharick JT, Walsh CM, Sprackling CM, Pasch CA, Pham DL, Esbona K, Choudhary A, Garcia-Valera R, Burkard ME, McGregor SM, Matkowskyj KA, Parikh AA, Meszoely IM, Kelley MC, Tsai S, Deming DA, Skala MC.,
Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment, Front Oncol. 2020 May 15;10:553. doi: 10.3389/fonc.2020.00553. eCollection 2020.
Yan, S. B., Um, S. L., Peek, V. L., Stephens, J. R., Zeng, W., Konicek, B. W., . . . Walgren, R. A. (2018).,
MET-targeting抗体(emibetuzumab)和激酶inhibitor (merestinib) as single agent or in combination in a cancer model bearing MET exon 14 skipping., Investigational New Drugs, 36(4), 536-544. doi:10.1007/s10637-017-0545-x [doi]
Yan P, Patel HJ, Sharma S, Corben A, Wang T, Panchal P, Yang C, Sun W, Araujo TL, Rodina A, Joshi S, Robzyk K, Gandu S, White JR, de Stanchina E, Modi S, Janjigian YY, Hill EG, Liu B, Erdjument-Bromage H, Neubert TA, Que NLS, Li Z, Gewirth DT, Taldone T, Chiosis G.,
Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone, Cell Rep. 2020 Jun 30;31(13):107840. doi: 10.1016/j.celrep.2020.107840.
Yan P, Patel HJ, Sharma S, Corben A, Wang T, Panchal P, Yang C, Sun W, Araujo TL, Rodina A, Joshi S, Robzyk K, Gandu S, White JR, de Stanchina E, Modi S, Janjigian YY, Hill EG, Liu B, Erdjument-Bromage H, Neubert TA, Que NLS, Li Z, Gewirth DT, Taldone T, Chiosis G.,
Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone, Cell Rep. 2020 Jun 30;31(13):107840. doi: 10.1016/j.celrep.2020.107840.
Morcillo, M. A., Garcia de Lucas, A., Oteo, M., Romero, E., Magro, N., Ibanez, M., . . . Martinez-Torrecuadrada, J. (2018).,
MT1-MMP as a PET imaging biomarker for pancreas cancer management., Contrast Media & Molecular Imaging, 2018, 8382148. doi:10.1155/2018/8382148 [doi]
Kumar, A., Dhar, S., Campanelli, G., Butt, N. A., Schallheim, J. M., Gomez, C. R., & Levenson, A. S. (2018),
MTA1 drives malignant progression and bone metastasis in prostate cancer., Molecular Oncology, 12(9), 1596-1607. doi:10.1002/1878-0261.12360 [doi]
Haedicke, K., Kozlova, D., Grafe, S., Teichgraber, U., Epple, M., & Hilger, I. (2015).,
Multifunctional calcium phosphate nanoparticles for combining near-infrared fluorescence imaging and photodynamic therapy, Acta Biomaterialia, 14, 197-207. doi:10.1016/j.actbio.2014.12.009 [doi]
Wang, P. Y., Swain, H. M., Kunkler, A. L., Chen, C. Y., Hutzen, B. J., Arnold, M. A., . . . Cripe, T. P. (2016).,
Neuroblastomas vary widely in their sensitivities to herpes simplex virotherapy unrelated to virus receptors and susceptibility., Gene Therapy, 23(2), 135-143. doi:10.1038/gt.2015.105 [doi]
Zheng ZY, Anurag M, Lei JT, Cao J, Singh P, Peng J, Kennedy H, Nguyen NC, Chen Y, Lavere P, Li J, Du XH, Cakar B, Song W, Kim BJ, Shi J, Seker S, Chan DW, Zhao GQ, Chen X, Banks KC, Lanman RB, Shafaee MN, Zhang XH, Vasaikar S, Zhang B, Hilsenbeck SG, Li W, Foulds CE, Ellis MJ, Chang EC.,
Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer, Cancer Cell. 2020 Mar 16;37(3):387-402.e7. doi: 10.1016/j.ccell.2020.02.003. Epub 2020 Mar 5.
Yu, X., Liu, F., Zeng, L., He, F., Zhang, R., Yan, S., . . . Chen, L. (2018).,
Niclosamide exhibits potent anticancer activity and synergizes with sorafenib in human renal cell cancer cells., Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 47(3), 957-971. doi:10.1159/000490140 [doi]
Bousquet墙E,贝尔纳多年代,帕庞L,曼奇尼M,足总bbrizio E, Goussard M, Ferrer I, Giry A, Quantin X, Pujol JL, Calvayrac O, Moll HP, Glasson Y, Pirot N, Turtoi A, Cañamero M, Wong KK, Yarden Y, Casanova E, Soria JC, Colinge J, Siebel CW, Mazieres J, Favre G, Paz-Ares L, Maraver A.,
Notch inhibition overcomes resistance to tyrosine kinase inhibitors in EGFR-driven lung adenocarcinoma, J Clin Invest. 2020 Feb 3;130(2):612-624. doi: 10.1172/JCI126896.
Chen, H., Jacobson, O., Niu, G., Weiss, I. D., Kiesewetter, D. O., Liu, Y., . . . Chen, X. (2017).,
Novel "add-on" molecule based on evans blue confers superior pharmacokinetics and transforms drugs to theranostic agents. Journal of Nuclear Medicin, Official Publication, Society of Nuclear Medicine, 58(4), 590-597. doi:10.2967/jnumed.116.182097 [doi]
Choi, A. H., O'Leary, M. P., Chaurasiya, S., Lu, J., Kim, S. I., Fong, Y., & Chen, N. G. (2018).,
Novel chimeric parapoxvirus CF189 as an oncolytic immunotherapy in triple-negative breast cancer, Surgery, 163(2), 336-342. doi:S0039-6060(17)30670-0 [pii]
Kanthala, S., Banappagari, S., Gokhale, A., Liu, Y. Y., Xin, G., Zhao, Y., & Jois, S. (2015).,
Novel peptidomimetics for inhibition of HER2:HER3 heterodimerization in HER2-positive breast cancer., Chemical Biology & Drug Design, 85(6), 702-714. doi:10.1111/cbdd.12453 [doi]
Chen Y, Li X, Mamouni K, Yang Y, Danaher A, White J, Liu H, Kucuk O, Gera L, Wu D.,
Novel small-molecule LG1836 inhibits the in vivo growth of castration-resistant prostate cancer, Prostate. 2020 Sep;80(12):993-1005. doi: 10.1002/pros.24032. Epub 2020 Jun 19.
Hegde, Ganapati V; de la Cruz, Cecile; Giltnane, Jennifer M; Crocker, Lisa; Venkatanarayan, Avinashnarayan; Schaefer, Gabriele; Dunlap, Debra; Hoeck, Joerg D; Piskol, Robert; Gnad, Florian; Modrusan, Zora; de Sauvage, Frederic J; Siebel, Christian W; Jackson, Erica L;,
NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma, eLife Vol.8, 2019
Somwar R, Hofmann NE, Smith B, Odintsov I, Vojnic M, Linkov I, Tam A, Khodos I, Mattar MS, de Stanchina E, Flynn D, Ladanyi M, Drilon A, Shinde U, Davare MA.,
NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors, Commun Biol. 2020 Dec 16;3(1):776. doi: 10.1038/s42003-020-01508-w.
Lagerweij, T., Dusoswa, S. A., Negrean, A., Hendrikx, E. M. L., de Vries, H. E., Kole, J., . . . Wurdinger, T. (2017).,
Optical clearing and fluorescence deep-tissue imaging for 3D quantitative analysis of the brain tumor microenvironment., Angiogenesis, 20(4), 533-546. doi:10.1007/s10456-017-9565-6 [doi]
Pearson, H. E., Iida, M., Orbuch, R. A., McDaniel, N. K., Nickel, K. P., Kimple, R. J., . . . Wheeler, D. L. (2018).,
Overcoming resistance to cetuximab with honokiol, A small-molecule polyphenol., Molecular Cancer Therapeutics, 17(1), 204-214. doi:10.1158/1535-7163.MCT-17-0384 [doi]
Lubik, A. A., Nouri, M., Truong, S., Ghaffari, M., Adomat, H. H., Corey, E., . . . Buttyan, R. (2017),
Paracrine sonic hedgehog signaling contributes significantly to acquired steroidogenesis in the prostate tumor microenvironment., International Journal of Cancer, 140(2), 358-369. doi:10.1002/ijc.30450 [doi]
Kamiyama, H., Rauenzahn, S., Shim, J. S., Karikari, C. A., Feldmann, G., Hua, L., . . . Eshleman, J. R. (2013).,
Personalized chemotherapy profiling using cancer cell lines from selectable mice., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 19(5), 1139-1146. doi:10.1158/1078-0432.CCR-12-2127 [doi]
Alexander, M. S., Wilkes, J. G., Schroeder, S. R., Buettner, G. R., Wagner, B. A., Du, J., . . . Cullen, J. J. (2018).,
Pharmacological ascorbate reduces radiation-induced normal tissue toxicity and enhances tumor radiosensitization in pancreatic cancer., Cancer Research, doi:canres.1680.2018 [pii]
Zhang, Y. J., Zhan, X., Wang, L., Ho, R. J., & Sasaki, T. (2015),
pH-responsive artemisinin dimer in lipid nanoparticles are effective against human breast cancer in a xenograft model., Journal of Pharmaceutical Sciences, 104(5), 1815-1824. doi:10.1002/jps.24407 [doi]
Pandya, K., Wyatt, D., Gallagher, B., Shah, D., Baker, A., Bloodworth, J., . . . Osipo, C. (2016).,
PKCalpha attenuates jagged-1-mediated notch signaling in ErbB-2-positive breast cancer to reverse trastuzumab resistance., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(1), 175-186. doi:10.1158/1078-0432.CCR-15-0179 [doi]
Galmarini, C. M., Martin, M., Bouchet, B. P., Guillen-Navarro, M. J., Martinez-Diez, M., Martinez-Leal, J. F., . . . Aviles, P. (2018).,
Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells., BMC Cancer, 18(1), 164-018-4086-2. doi:10.1186/s12885-018-4086-2 [doi]
Carlier, C., Strese, S., Viktorsson, K., Velander, E., Nygren, P., Uustalu, M., . . . Gullbo, J. (2016).,
Preclinical activity of melflufen (J1) in ovarian cancer., Oncotarget, 7(37), 59322-59335. doi:10.18632/oncotarget.11163 [doi]
Scribner JA, Brown JG, Son T, Chiechi M, Li P, Sharma S, Li H, De Costa A, Li Y, Chen Y, Easton A, Yee-Toy NC, Chen FZ, Gorlatov S, Barat B, Huang L, Wolff CR, Hooley J, Hotaling TE, Gaynutdinov T, Ciccarone V, Tamura J, Koenig S, Moore PA, Bonvini E, Loo D.,
Preclinical Development of MGC018, a Duocarmycin-based Antibody-drug Conjugate Targeting B7-H3 for Solid Cancer, Mol Cancer Ther. 2020 Sep 23:molcanther.0116.2020. doi: 10.1158/1535-7163.MCT-20-0116. Online ahead of print.
Hammer S, Hagemann UB, Zitzmann-Kolbe S, Larsen A, Ellingsen C, Geraudie S, Grant D, Indrevoll B, Smeets R, von Ahsen O, Kristian A, Lejeune P, Hennekes H, Karlsson J, Bjerke RM, Ryan OB, Cuthbertson AS, Mumberg D.,
Preclinical Efficacy of a PSMA-Targeted Thorium-227 Conjugate (PSMA-TTC), a Targeted Alpha Therapy for Prostate Cancer, Clin Cancer Res. 2020 Apr 15;26(8):1985-1996. doi: 10.1158/1078-0432.CCR-19-2268. Epub 2019 Dec 12.
Verreault, M., Schmitt, C., Goldwirt, L., Pelton, K., Haidar, S., Levasseur, C., . . . Idbaih, A. (2016).,
Preclinical efficacy of the MDM2 inhibitor RG7112 in MDM2-amplified and TP53 wild-type glioblastomas, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(5), 1185-1196. doi:10.1158/1078-0432.CCR-15-1015 [doi]
Harper, J., Lloyd, C., Dimasi, N., Toader, D., Marwood, R., Lewis, L., . . . Kamal, A. (2017).,
Preclinical evaluation of MEDI0641, a pyrrolobenzodiazepine-conjugated antibody-drug conjugate targeting 5T4., Molecular Cancer Therapeutics, 16(8), 1576-1587. doi:10.1158/1535-7163.MCT-16-0825 [doi]
Waters, A. M., Stewart, J. E., Atigadda, V. R., Mroczek-Musulman, E., Muccio, D. D., Grubbs, C. J., & Beierle, E. A. (2016).,
Preclinical evaluation of UAB30 in pediatric renal and hepatic malignancies., Molecular Cancer Therapeutics, 15(5), 911-921. doi:10.1158/1535-7163.MCT-15-0521 [doi]
Segatto, I., Massarut, S., Boyle, R., Baldassarre, G., Walker, D., & Belletti, B. (2016).,
Preclinical validation of a novel compound targeting p70S6 kinase in breast cancer., Aging, 8(5), 958-976. doi:10.18632/aging.100954 [doi]
Advani, S. J., Buckel, L., Chen, N. G., Scanderbeg, D. J., Geissinger, U., Zhang, Q., . . . Szalay, A. A. (2012).,
Preferential replication of systemically delivered oncolytic vaccinia virus in focally irradiated glioma xenografts, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(9), 2579-2590. doi:10.1158/1078-0432.CCR-11-2394 [doi]
Avasarala, S., Van Scoyk, M., Karuppusamy Rathinam, M. K., Zerayesus, S., Zhao, X., Zhang, W., . . . Bikkavilli, R. K. (2015).,
PRMT1 is a novel regulator of epithelial-mesenchymal-transition in non-small cell lung cancer, The Journal of Biological Chemistry, 290(21), 13479-13489. doi:10.1074/jbc.M114.636050 [doi]
Zhang, Y., Thayele Purayil, H., Black, J. B., Fetto, F., Lynch, L. D., Masannat, J. N., & Daaka, Y. (2017).,
Prostaglandin E2 receptor 4 mediates renal cell carcinoma intravasation and metastasis., Cancer Letters, 391, 50-58. doi:S0304-3835(17)30029-0 [pii]
Dou, Liping; Yan, Fei; Pang, Jiuxia; Zheng, Dehua; Li, Dandan; Gao, Li; Wang, Lijun; Xu, Yihan; Shi, Jinlong; Wang, Qian; Zhou, Lei; Shen, Na; Singh, Puja; Wang, Lili; Li, Yonghui; Gao, Yvchi; Liu, Tao; Chen, Chongjian; Al-Kali, Aref; Litzow, Mark R; Chi, Young-In; Bode, Ann M; Liu, Chunhui; Huang, Haojie; Liu, Daihong; Marcucci, Guido; Liu, Shujun; Yu, Li;,
Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia., Nature communications Vol.10, 2019
Tozzi M, Sørensen CE, Magni L, Christensen NM, Bouazzi R, Buch CM, Stefanini M, Duranti C, Arcangeli A, Novak I.,
Proton Pump Inhibitors Reduce Pancreatic Adenocarcinoma Progression by Selectively Targeting H(+), K(+)-ATPases in Pancreatic Cancer and Stellate Cells, Cancers (Basel). 2020 Mar 10;12(3):640. doi: 10.3390/cancers12030640.
Kenny HA, Lal-Nag M, Shen M, Kara B, Nahotko DA, Wroblewski K, Fazal S, Chen S, Chiang CY, Chen YJ, Brimacombe KR, Marugan J, Ferrer M, Lengyel E.,
Quantitative High-Throughput Screening Using an Organotypic Model Identifies Compounds that Inhibit Ovarian Cancer Metastasis, Mol Cancer Ther. 2020 Jan;19(1):52-62. doi: 10.1158/1535-7163.MCT-19-0052. Epub 2019 Sep 27.
Gupta K, Vuckovic I, Zhang S, Xiong Y, Carlson BL, Jacobs J, Olson I, Petterson XM, Macura SI, Sarkaria J, Burns TC.,
Radiation Induced Metabolic Alterations Associate With Tumor Aggressiveness and Poor Outcome in Glioblastoma, Front Oncol. 2020 May 5;10:535. doi: 10.3389/fonc.2020.00535. eCollection 2020.
Deshayes, E., Ladjohounlou, R., Le Fur, P., Pichard, A., Lozza, C., Boudousq, V., . . . Pouget, J. P. (2018).,
Radiolabeled antibodies against mullerian-inhibiting substance receptor, type II: New tools for a theranostic approach in ovarian cancer., Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 59(8), 1234-1242. doi:10.2967/jnumed.118.208611 [doi]
Jiang, D., Im, H. J., Sun, H., Valdovinos, H. F., England, C. G., Ehlerding, E. B., . . . Cai, W. (2017).,
Radiolabeled pertuzumab for imaging of human epidermal growth factor receptor 2 expression in ovarian cancer., European Journal of Nuclear Medicine and Molecular Imaging, 44(8), 1296-1305. doi:10.1007/s00259-017-3663-y [doi]
Albertoni, C., Leoni, B., Rosi, A., D'Alessio, V., Carollo, V., Spagnoli, L. G., . . . De Santis, R. (2015).,
Radionuclide therapy of unresectable tumors with AvidinOX and (90)Y-biotinDOTA: Tongue cancer paradigm., Cancer Biotherapy & Radiopharmaceuticals, 30(7), 291-298. doi:10.1089/cbr.2015.1837 [doi]
Schoenfeld, J. D., Sibenaller, Z. A., Mapuskar, K. A., Bradley, M. D., Wagner, B. A., Buettner, G. R., . . . Allen, B. G. (2018).,
Redox active metals and H2O2 mediate the increased efficacy of pharmacological ascorbate in combination with gemcitabine or radiation in pre-clinical sarcoma models., Redox Biology, 14, 417-422. doi:S2213-2317(17)30582-7 [pii]
Mantis, C., Kandela, I., Aird, F., & Reproducibility Project: Cancer Biology. (2017).,
Replication study: Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs., Elife, 6, 10.7554/eLife.17584. doi:10.7554/eLife.17584 [doi]
Kizilbash, S. H., Gupta, S. K., Chang, K., Kawashima, R., Parrish, K. E., Carlson, B. L., . . . Sarkaria, J. N. (2017).,
Restricted delivery of talazoparib across the blood-brain barrier limits the sensitizing effects of PARP inhibition on temozolomide therapy in glioblastoma., Molecular Cancer Therapeutics, 16(12), 2735-2746. doi:10.1158/1535-7163.MCT-17-0365 [doi]
Smith, Bryan D; Kaufman, Michael D; Lu, Wei-Ping; Gupta, Anu; Leary, Cynthia B; Wise, Scott C; Rutkoski, Thomas J; Ahn, Yu Mi; Al-Ani, Gada; Bulfer, Stacie L; Caldwell, Timothy M; Chun, Lawrence; Ensinger, Carol L; Hood, Molly M; McKinley, Arin; Patt, William C; Ruiz-Soto, Rodrigo; Su, Ying; Telikepalli, Hanumaiah; Town, Ajia; Turner, Benjamin A; Vogeti, Lakshminarayana; Vogeti, Subha; Yates, Karen; Janku, Filip; Abdul Razak, Albiruni Ryan; Rosen, Oliver; Heinrich, Michael C; Flynn, Daniel L;,
Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants., Cancer cell Vol.35, 2019
Mi, S., Lin, M., Brouwer-Visser, J., Heim, J., Smotkin, D., Hebert, T., . . . Huang, G. S. (2016),
RNA-seq identification of RACGAP1 as a metastatic driver in uterine carcinosarcoma., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(18), 4676-4686. doi:10.1158/1078-0432.CCR-15-2116 [doi]
Cai, Demin; Wang, Junjian; Gao, Bei; Li, Jin; Wu, Feng; Zou, June X; Xu, Jianzhen; Jiang, Yuqian; Zou, Hongye; Huang, Zenghong; Borowsky, Alexander D; Bold, Richard J; Lara, Primo N; Li, Jian Jian; Chen, Xinbin; Lam, Kit S; To, Ka-Fai; Kung, Hsing-Jien; Fiehn, Oliver; Zhao, Ruqian; Evans, Ronald M; Chen, Hong-Wu;,
ROR? is a targetable master regulator of cholesterol biosynthesis in a cancer subtype., Nature communications Vol.10, 2019
Winter, U., Mena, H. A., Negrotto, S., Arana, E., Pascual-Pasto, G., Laurent, V., . . . Schaiquevich, P. (2016).,
Schedule-dependent antiangiogenic and cytotoxic effects of chemotherapy on vascular endothelial and retinoblastoma cells., PloS One, 11(7), e0160094. doi:10.1371/journal.pone.0160094 [doi]
Robles, A. J., Cai, S., Cichewicz, R. H., & Mooberry, S. L. (2016).,
Selective activity of deguelin identifies therapeutic targets for androgen receptor-positive breast cancer., Breast Cancer Research and Treatment, 157(3), 475-488. doi:10.1007/s10549-016-3841-9 [doi]
Yu, Z., He, S., Wang, D., Patel, H. K., Miller, C. P., Brown, J. L., . . . Saeh, J. C. (2017),
Selective androgen receptor modulator RAD140 inhibits the growth of Androgen/Estrogen receptor-positive breast cancer models with a distinct mechanism of action., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(24), 7608-7620. doi:10.1158/1078-0432.CCR-17-0670 [doi]
Kausar, T., Schreiber, J. S., Karnak, D., Parsels, L. A., Parsels, J. D., Davis, M. A., . . . Morgan, M. A. (2015).,
Sensitization of pancreatic cancers to gemcitabine chemoradiation by WEE1 kinase inhibition depends on homologous recombination repair, Neoplasia (New York, N.Y.), 17(10), 757-766. doi:10.1016/j.neo.2015.09.006 [doi]
Kietzman, William B; Graham, Garrett T; Ory, Virginie; Sharif, Ghada M; Kushner, Max H; Gallanis, Gregory T; Kallakury, Bhaskar; Wellstein, Anton; Riegel, Anna T;,
Short- and Long-Term Effects of CDK4/6 Inhibition on Early-Stage Breast Cancer., Molecular cancer therapeutics Vol.18, 2019
Leelatian, N., Doxie, D. B., Greenplate, A. R., Mobley, B. C., Lehman, J. M., Sinnaeve, J., . . . Irish, J. M. (2017).,
Single cell analysis of human tissues and solid tumors with mass cytometry., Cytometry.Part B, Clinical Cytometry, 92(1), 68-78. doi:10.1002/cyto.b.21481 [doi]
Tchoghandjian, A., Jennewein, C., Eckhardt, I., Momma, S., Figarella-Branger, D., & Fulda, S. (2014).,
Smac mimetic promotes glioblastoma cancer stem-like cell differentiation by activating NF-kappaB., Cell Death and Differentiation, 21(5), 735-747. doi:10.1038/cdd.2013.200 [doi]
Yoshida, K., Toden, S., Weng, W., Shigeyasu, K., Miyoshi, J., Turner, J., . . . Goel, A. (2017).,
SNORA21 - an oncogenic small nucleolar RNA, with a prognostic biomarker potential in human colorectal cancer., Ebiomedicine, 22, 68-77. doi:S2352-3964(17)30282-7 [pii]
Bach, P., Abel, T., Hoffmann, C., Gal, Z., Braun, G., Voelker, I., . . . Buchholz, C. J. (2013).,
Specific elimination of CD133+ tumor cells with targeted oncolytic measles virus., Cancer Research, 73(2), 865-874. doi:10.1158/0008-5472.CAN-12-2221 [doi]
Li, X., Wu, J. B., Li, Q., Shigemura, K., Chung, L. W., & Huang, W. C. (2016),
SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-myc in prostate cancer., Oncotarget, 7(11), 12869-12884. doi:10.18632/oncotarget.7331 [doi]
Trotta F, Avena P, Chimento A, Rago V, De Luca A, Sculco S, Nocito MC, Malivindi R, Fallo F, Pezzani R, Pilon C, Lasorsa FM, Barile SN, Palmieri L, Lerario AM, Pezzi V, Casaburi I, Sirianni R.,
Statins Reduce Intratumor Cholesterol Affecting Adrenocortical Cancer Growth, Mol Cancer Ther. 2020 Sep;19(9):1909-1921. doi: 10.1158/1535-7163.MCT-19-1063. Epub 2020 Jun 16.
Gao, F., Alwhaibi, A., Sabbineni, H., Verma, A., Eldahshan, W., & Somanath, P. R. (2017).,
Suppression of Akt1-beta-catenin pathway in advanced prostate cancer promotes TGFbeta1-mediated epithelial to mesenchymal transition and metastasis., Cancer Letters, 402, 177-189. doi:S0304-3835(17)30374-9 [pii]
Vanderburgh, Joseph P; Kwakwa, Kristin A; Werfel, Thomas A; Merkel, Alyssa R; Gupta, Mukesh K; Johnson, Rachelle W; Guelcher, Scott A; Duvall, Craig L; Rhoades, Julie A;,
Systemic delivery of a Gli inhibitor via polymeric nanocarriers inhibits tumor-induced bone disease, Journal of controlled release : official journal of the Controlled Release Society Vol.311-312, 2019
Babae, N., Bourajjaj, M., Liu, Y., Van Beijnum, J. R., Cerisoli, F., Scaria, P. V., . . . Schiffelers, R. M. (2014).,
Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma., Oncotarget, 5(16), 6687-6700. doi:2235 [pii]
Rudnick-Glick, S., Corem-Salkmon, E., Grinberg, I., & Margel, S. (2016).,
Targeted drug delivery of near IR fluorescent doxorubicin-conjugated poly(ethylene glycol) bisphosphonate nanoparticles for diagnosis and therapy of primary and metastatic bone cancer in a mouse model., Journal of Nanobiotechnology, 14(1), 80-016-0233-6. doi:10.1186/s12951-016-0233-6 [doi]
Chan, C. M., Jing, X., Pike, L. A., Zhou, Q., Lim, D. J., Sams, S. B., . . . Schweppe, R. E. (2012).,
Targeted inhibition of src kinase with dasatinib blocks thyroid cancer growth and metastasis., . Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(13), 3580-3591. doi:10.1158/1078-0432.CCR-11-3359 [doi]
Sen, T., Tong, P., Diao, L., Li, L., Fan, Y., Hoff, J., . . . Byers, L. A. (2017).,
Targeting AXL and mTOR pathway overcomes primary and acquired resistance to WEE1 inhibition in small-cell lung cancer, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(20), 6239-6253. doi:10.1158/1078-0432.CCR-17-1284 [doi]
Lallous, N., Leblanc, E., Munuganti, R. S., Hassona, M. D., Nakouzi, N. A., Awrey, S., . . . Cherkasov, A. (2016).,
Targeting binding function-3 of the androgen receptor blocks its co-chaperone interactions, nuclear translocation, and activation., Molecular Cancer Therapeutics, 15(12), 2936-2945. doi:1535-7163.MCT-16-0354 [pii]
Pittala, S., Krelin, Y., & Shoshan-Barmatz, V. (2018),
Targeting liver cancer and associated pathologies in mice with a mitochondrial VDAC1-based peptide., Neoplasia (New York, N.Y.), 20(6), 594-609. doi:S1476-5586(17)30508-0 [pii]
de Lucas, A. G., Schuhmacher, A. J., Oteo, M., Romero, E., Camara, J. A., de Martino, A., . . . Mulero, F. (2016),
Targeting MT1-MMP as an ImmunoPET-based strategy for imaging gliomas., PloS One, 11(7), e0158634. doi:10.1371/journal.pone.0158634 [doi]
Stafman, L. L., Mruthyunjayappa, S., Waters, A. M., Garner, E. F., Aye, J. M., Stewart, J. E., . . . Beierle, E. A. (2018).,
Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma., Oncotarget, 9(32), 22665-22679. doi:10.18632/oncotarget.25205 [doi]
Stafman, Laura L; Williams, Adele P; Garner, Evan F; Aye, Jamie M; Stewart, Jerry E; Yoon, Karina J; Whelan, Kimberly; Beierle, Elizabeth A;,
Targeting PIM Kinases Affects Maintenance of CD133 Tumor Cell Population in Hepatoblastoma., Translational oncology Vol.12, 2019
de Boer, D. V., Martens-de Kemp, S. R., Buijze, M., Stigter-van Walsum, M., Bloemena, E., Dietrich, R., . . . Brakenhoff, R. H. (2017).,
Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck., Oncotarget, 8(58), 97928-97940. doi:10.18632/oncotarget.17880 [doi]
Alimova, I., Pierce, A. M., Harris, P., Donson, A., Birks, D. K., Prince, E., . . . Vibhakar, R. (2017).,
Targeting polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor, Oncotarget, 8(57), 97290-97303. doi:10.18632/oncotarget.21932 [doi]
Sen, M., Joyce, S., Panahandeh, M., Li, C., Thomas, S. M., Maxwell, J., . . . Grandis, J. R. (2012),
Targeting Stat3 abrogates EGFR inhibitor resistance in cancer., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(18), 4986-4996. doi:10.1158/1078-0432.CCR-12-0792 [doi]
Jimbo, M., Blanco, F. F., Huang, Y. H., Telonis, A. G., Screnci, B. A., Cosma, G. L., . . . Brody, J. R. (2015),
Targeting the mRNA-binding protein HuR impairs malignant characteristics of pancreatic ductal adenocarcinoma cells, Oncotarget, 6(29), 27312-27331. doi:10.18632/oncotarget.4743 [doi]
Sinha S, Dwivedi N, Tao S, Jamadar A, Kakade VR, Neil MO, Weiss RH, Enders J, Calvet JP, Thomas SM, Rao R.,
Targeting the vasopressin type-2 receptor for renal cell carcinoma therapy, Oncogene. 2020 Feb;39(6):1231-1245. doi: 10.1038/s41388-019-1059-0. Epub 2019 Oct 15.
Capone E, Lamolinara A, Pastorino F, Gentile R, Ponziani S, Di Vittorio G, D'Agostino D, Bibbò S, Rossi C, Piccolo E, Iacobelli V, Lattanzio R, Panella V, Sallese M, De Laurenzi V, Giansanti F, Sala A, Iezzi M, Ponzoni M, Ippoliti R, Iacobelli S, Sala G.,
Targeting Vesicular LGALS3BP by an Antibody-Drug Conjugate as Novel Therapeutic Strategy for Neuroblastoma, Cancers (Basel). 2020 Oct 15;12(10):2989. doi: 10.3390/cancers12102989.
Jin, U. H., Lee, S. O., Pfent, C., & Safe, S. (2014).,
The aryl hydrocarbon receptor ligand omeprazole inhibits breast cancer cell invasion and metastasis., BMC Cancer, 14, 498-2407-14-498. doi:10.1186/1471-2407-14-498 [doi]
Morell, C., Bort, A., Vara, D., Ramos-Torres, A., Rodriguez-Henche, N., & Diaz-Laviada, I. (2016).,
The cannabinoid WIN 55,212-2 prevents neuroendocrine differentiation of LNCaP prostate cancer cells., Prostate Cancer and Prostatic Diseases, 19(3), 248-257. doi:10.1038/pcan.2016.19 [doi]
van Senten, Jeffrey R; Bebelman, Maarten P; Fan, Tian Shu; Heukers, Raimond; Bergkamp, Nick D; van Gasselt, Puck; Langemeijer, Ellen V; Slinger, Erik; Lagerweij, Tonny; Rahbar, Afsar; Stigter-van Walsum, Marijke; Maussang, David; Leurs, Rob; Musters, René J P; van Dongen, Guus A M S; Söderberg-Nauclér, Cecilia; Würdinger, Thomas; Siderius, Marco; Smit, Martine J;,
The human cytomegalovirus-encoded G protein-coupled receptor UL33 exhibits oncomodulatory properties, . The Journal of biological chemistry Vol.294, 2019
Laprevotte, E., Cochaud, S., du Manoir, S., Lapierre, M., Dejou, C., Philippe, M., . . . Bonnefoy, N. (2017).,
The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway, Oncotarget, 8(69), 113360-113372. doi:10.18632/oncotarget.23008 [doi]
Canon, J., Osgood, T., Olson, S. H., Saiki, A. Y., Robertson, R., Yu, D., . . . Radinsky, R. (2015).,
The MDM2 inhibitor AMG 232 demonstrates robust antitumor efficacy and potentiates the activity of p53-inducing cytotoxic agents, Molecular Cancer Therapeutics, 14(3), 649-658. doi:10.1158/1535-7163.MCT-14-0710 [doi]
Canon, J., Osgood, T., Olson, S. H., Saiki, A. Y., Robertson, R., Yu, D., . . . Radinsky, R. (2015),
The MDM2 inhibitor AMG 232 demonstrates robust antitumor efficacy and potentiates the activity of p53-inducing cytotoxic agents., Molecular Cancer Therapeutics, 14(3), 649-658. doi:10.1158/1535-7163.MCT-14-0710 [doi]
Schuller, A. G., Barry, E. R., Jones, R. D., Henry, R. E., Frigault, M. M., Beran, G., . . . D'Cruz, C. M. (2015),
The MET inhibitor AZD6094 (savolitinib, HMPL-504) induces regression in papillary renal cell carcinoma patient-derived xenograft models., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(12), 2811-2819. doi:10.1158/1078-0432.CCR-14-2685 [doi]
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology Vol.48, 2019,
The novel capsazepine analog, CIDD-99, significantly inhibits oral squamous cell carcinoma in vivo through a TRPV1-independent induction of ER stress, mitochondrial dysfunction, and apoptosis., De La Chapa, Jorge J; Singha, Prajjal K; Self, Kristen K; Sallaway, McKay L; McHardy, Stanton F; Hart, Matthew J; McGuff, Howard Stan; Valdez, Matthew C; Ruiz, Francisco; Polusani, Srikanth R; Gonzales, Cara B;
Martin-Fernandez, M., Valencia, K., Zandueta, C., Ormazabal, C., Martinez-Canarias, S., Lecanda, F., & de la Piedra, C. (2017),
The usefulness of bone biomarkers for monitoring treatment disease: A comparative study in osteolytic and osteosclerotic bone metastasis models., Translational Oncology, 10(2), 255-261. doi:S1936-5233(16)30223-6 [pii]
Barbhuiya, M. A., Mirando, A. C., Simons, B. W., Lemtiri-Chlieh, G., Green, J. J., Popel, A. S., . . . Tran, P. T. (2017).,
Therapeutic potential of an anti-angiogenic multimodal biomimetic peptide in hepatocellular carcinoma, Oncotarget, 8(60), 101520-101534. doi:10.18632/oncotarget.21148 [doi]
Redko, B., Tuchinsky, H., Segal, T., Tobi, D., Luboshits, G., Ashur-Fabian, O., . . . Gellerman, G. (2017).,
Toward the development of a novel non-RGD cyclic peptide drug conjugate for treatment of human metastatic melanoma, Oncotarget, 8(1), 757-768. doi:10.18632/oncotarget.12748 [doi]
Kiesel, B. F., Parise, R. A., Guo, J., Huryn, D. M., Johnston, P. A., Colombo, R., . . . Eiseman, J. L. (2016).,
Toxicity, pharmacokinetics and metabolism of a novel inhibitor of IL-6-induced STAT3 activation., Cancer Chemotherapy and Pharmacology, 78(6), 1225-1235. doi:10.1007/s00280-016-3181-9 [doi]
Zhang, Z., Li, Z., Wu, X., Zhang, C. F., Calway, T., He, T. C., . . . Yuan, C. S. (2015).,
TRAIL pathway is associated with inhibition of colon cancer by protopanaxadiol., Journal of Pharmacological Sciences, 127(1), 83-91. doi:10.1016/j.jphs.2014.11.003 [doi]
Theunissen, J. W., Cai, A. G., Bhatti, M. M., Cooper, A. B., Avery, A. D., Dorfman, R., . . . Migone, T. S. (2018).,
Treating tissue factor-positive cancers with antibody-drug conjugates that do not affect blood clotting., Molecular Cancer Therapeutics, doi:molcanther.0471.2018 [pii]
Ostler, K. R., Yang, Q., Looney, T. J., Zhang, L., Vasanthakumar, A., Tian, Y., . . . Godley, L. A. (2012).,
Truncated DNMT3B isoform DNMT3B7 suppresses growth, induces differentiation, and alters DNA methylation in human neuroblastoma., Cancer Research, 72(18), 4714-4723. doi:10.1158/0008-5472.CAN-12-0886 [doi]
Dziegielewska, B., Casarez, E. V., Yang, W. Z., Gray, L. S., Dziegielewski, J., & Slack-Davis, J. K. (2016),
T-type Ca2+ channel inhibition sensitizes ovarian cancer to carboplatin., Molecular Cancer Therapeutics, 15(3), 460-470. doi:10.1158/1535-7163.MCT-15-0456 [doi]
Lingasamy P, Tobi A, Kurm K, Kopanchuk S, Sudakov A, Salumäe M, Rätsep T, Asser T, Bjerkvig R, Teesalu T.,
Tumor-penetrating peptide for systemic targeting of Tenascin-C, Sci Rep. 2020 Apr 2;10(1):5809. doi: 10.1038/s41598-020-62760-y.
Emmenegger, U., Francia, G., Chow, A., Shaked, Y., Kouri, A., Man, S., & Kerbel, R. S. (2011).,
Tumors that acquire resistance to low-dose metronomic cyclophosphamide retain sensitivity to maximum tolerated dose cyclophosphamide, Neoplasia (New York, N.Y.), 13(1), 40-48.
Brunetti, J., Pillozzi, S., Falciani, C., Depau, L., Tenori, E., Scali, S., . . . Bracci, L. (2015).,
Tumor-selective peptide-carrier delivery of paclitaxel increases in vivo activity of the drug, Scientific Reports, 5, 17736. doi:10.1038/srep17736 [doi]
Yuan, B., Cheng, L., Gupta, K., Chiang, H. C., Gupta, H. B., Sareddy, G. R., . . . Li, R. (2016).,
Tyrosine phosphorylation regulates ERbeta ubiquitination, protein turnover, and inhibition of breast cancer., Oncotarget, 7(27), 42585-42597. doi:10.18632/oncotarget.10018 [doi]
威廉姆斯,阿黛尔P;Garner, Evan F; Stafman, Laura L; Aye, Jamie M; Quinn, Colin H; Marayati, Raoud; Stewart, Jerry E; Atigadda, Venkatram R; Mroczek-Musulman, Elizabeth; Moore, Blake P; Beierle, Elizabeth A; Friedman, Gregory K;,
UAB30, A Novel Rexinoid Agonist, Decreases Stemness In Group 3 Medulloblastoma Human Cell Line Xenografts., Translational oncology Vol.12, 2019
阮,你;樱桃白兰地,布莱恩·詹姆斯;Asaka提价;Nabi, Karim; Quinones, Addison; Tan, Jessica; Antonio, Marjorie Justine; Camelo, Felipe; Li, Ting; Nguyen, Stephanie; Hoang, Giang; Nguyen, Kiet; Udupa, Sunag; Sazeides, Christos; Shen, Yao-An; Elgogary, Amira; Reyes, Juvenal; Zhao, Liang; Kleensang, Andre; Chaichana, Kaisorn Lee; Hartung, Thomas; Betenbaugh, Michael J; Marie, Suely K; Jung, Jin G; Wang, Tian-Li; Gabrielson, Edward; Le, Anne;,
Uncovering the Role of N-Acetyl-Aspartyl-Glutamate as a Glutamate Reservoir in Cance, Cell reports Vol.27, 2019
Richter, K., Paakkola, T., Mennerich, D., Kubaichuk, K., Konzack, A., Kippari, H. A., . . . Kietzmann, T. (2018),
USP28 deficiency promotes breast and liver carcinogenesis as well as tumor angiogenesis in a HIF-independent manner., Molecular Cancer Research : MCR, 16(6), 1000-1012. doi:10.1158/1541-7786.MCR-17-0452 [doi]
Gholami, S., Chen, C. H., Lou, E., Belin, L. J., Fujisawa, S., Longo, V. A., . . . Fong, Y. (2014),
Vaccinia virus GLV-1h153 in combination with 131I shows increased efficiency in treating triple-negative breast cancer., FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology, 28(2), 676-682. doi:10.1096/fj.13-237222 [doi]
Gruslova, A., Cavazos, D. A., Miller, J. R., Breitbart, E., Cohen, Y. C., Bangio, L., . . . Brenner, A. J. (2015).,
VB-111: A novel anti-vascular therapeutic for glioblastoma multiforme, Journal of Neuro-Oncology, 124(3), 365-372. doi:10.1007/s11060-015-1853-7 [doi]
O'Steen, S., Green, D. J., Gopal, A. K., Orozco, J. J., Kenoyer, A. L., Lin, Y., . . . Press, O. W. (2017).,
Venetoclax synergizes with radiotherapy for treatment of B-cell lymphomas., Cancer Research, 77(14), 3885-3893. doi:10.1158/0008-5472.CAN-17-0082 [doi]
Patil, S. S., Gentschev, I., Adelfinger, M., Donat, U., Hess, M., Weibel, S., . . . Szalay, A. A. (2012).,
Virotherapy of canine tumors with oncolytic vaccinia virus GLV-1h109 expressing an anti-VEGF single-chain antibody, PloS One, 7(10), e47472. doi:10.1371/journal.pone.0047472 [doi]
Kim SI, Chaurasiya S, Park AK, Kang S, Lu J, Woo Y, Yin HH, Yin Z, Fong Y, Warner SG.,
Vitamin D as a Primer for Oncolytic Viral Therapy in Colon Cancer Models, Int J Mol Sci. 2020 Oct 3;21(19):7326. doi: 10.3390/ijms21197326.
Stein, A. P., Swick, A. D., Smith, M. A., Blitzer, G. C., Yang, R. Z., Saha, S., . . . Kimple, R. J. (2015).,
Xenograft assessment of predictive biomarkers for standard head and neck cancer therapies, Cancer Medicine, 4(5), 699-712. doi:10.1002/cam4.387 [doi]
Zhang, Q., Sun, X., Yang, J., Ding, H., LeBrun, D., Ding, K., . . . Li, M. (2015).,
胰腺ca的ZIP4沉默改善骨质流失ncer., Oncotarget, 6(28), 26041-26051. doi:10.18632/oncotarget.4667 [doi]
Cam M, Charan M, Welker AM, Dravid P, Studebaker AW, Leonard JR, Pierson CR, Nakano I, Beattie CE, Hwang EI, Kambhampati M, Nazarian J, Finlay JL, Cam H.,
ΔNp73/ETS2 complex drives glioblastoma pathogenesis- targeting downstream mediators by rebastinib prolongs survival in preclinical models of glioblastoma, Neuro Oncol. 2020 Mar 5;22(3):345-356. doi: 10.1093/neuonc/noz190.
