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Aging

Beccari, S., Valero, J., Maletic-Savatic, M., & Sierra, A. (2017).,A simulation model of neuroprogenitor proliferation dynamics predicts age-related loss of hippocampal neurogenesis but not astrogenesis., Scientific Reports, 7(1), 16528-017-16466-3. doi:10.1038/s41598-017-16466-3 [doi]
Bauernfeind, F., Niepmann, S., Knolle, P. A., & Hornung, V. (2016).,Aging-associated TNF production primes inflammasome activation and NLRP3-related metabolic disturbances., Journal of Immunology (Baltimore, Md.: 1950), 197(7), 2900-2908. doi:10.4049/jimmunol.1501336 [doi]
Panagiotou, M., Vyazovskiy, V. V., Meijer, J. H., & Deboer, T. (2017).,Differences in electroencephalographic non-rapid-eye movement sleep slow-wave characteristics between young and old mice, Scientific Reports, 7, 43656. doi:10.1038/srep43656 [doi]
Wolf, G., Lotan, A., Lifschytz, T., Ben-Ari, H., Kreisel Merzel, T., Tatarskyy, P., . . . Lerer, B. (2017).,Differentially severe cognitive effects of compromised cerebral blood flow in aged mice: Association with myelin degradation and microglia activation., Frontiers in Aging Neuroscience, 9, 191. doi:10.3389/fnagi.2017.00191 [doi]
Panagiotou, M., Papagiannopoulos, K., Rohling, J. H. T., Meijer, J. H., & Deboer, T. (2018).,How old is your brain? slow-wave activity in non-rapid-eye-movement sleep as a marker of brain rejuvenation after long-term exercise in mice., Frontiers in Aging Neuroscience, 10, 233. doi:10.3389/fnagi.2018.00233 [doi]
Nitzan, Keren; Benhamron, Sandrine; Valitsky, Michael; Kesner, Eyal E; Lichtenstein, Michal; Ben-Zvi, Ayal; Ella, Ezra; Segalstein, Yehudit; Saada, Ann; Lorberboum-Galski, Haya; Rosenmann, Hanna;,Mitochondrial Transfer Ameliorates Cognitive Deficits, Neuronal Loss, and Gliosis in Alzheimers Disease Mice, Journal of Alzheimer's disease : JAD Vol.72, 2019
Davis, H. M., Aref, M. W., Aguilar-Perez, A., Pacheco-Costa, R., Allen, K., Valdez, S., . . . Plotkin, L. I. (2018).,x43 overexpression in osteocytes prevents osteocyte apoptosis and preserves cortical bone quality in aging mice., JBMR Plus, 2(4), 206-216. doi:10.1002/jbm4.10035 [doi]

Alcoholism

Lopez-Jimenez, A., Walter, N. A., Gine, E., Santos, A., Echeverry-Alzate, V., Buhler, K. M., . . . Lopez-Moreno, J. A. (2013).,A spontaneous deletion of alpha-synuclein is associated with an increase in CB1 mRNA transcript and receptor expression in the hippocampus and amygdala: Effects on alcohol consumption., Synapse (New York, N.Y.), 67(6), 280-289. doi:10.1002/syn.21639 [doi]
Laitakari A, Tapio J, Mäkelä KA, Herzig KH, Dengler F, Gylling H, Walkinshaw G, Myllyharju J, Dimova EY, Serpi R, Koivunen P.,HIF-P4H-2 inhibition enhances intestinal fructose metabolism and induces thermogenesis protecting against NAFLD, J Mol Med (Berl). 2020 May;98(5):719-731. doi: 10.1007/s00109-020-01903-0. Epub 2020 Apr 15.

Alpha synuclein

Zaltieri, M., Grigoletto, J., Longhena, F., Navarria, L., Favero, G., Castrezzati, S., . . . Bellucci, A. (2015).,Alpha-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons., Journal of Cell Science, 128(13), 2231-2243. doi:10.1242/jcs.157867 [doi]
Zaltieri, M., Grigoletto, J., Longhena, F., Navarria, L., Favero, G., Castrezzati, S., . . . Bellucci, A. (2015).,Alpha-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons., Journal of Cell Science, 128(13), 2231-2243. doi:10.1242/jcs.157867 [doi]
Liron, T., Raphael, B., Hiram-Bab, S., Bab, I. A., & Gabet, Y. (2018),Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes., . Journal of Cellular Physiology, 233(1), 371-377. doi:10.1002/jcp.25895 [doi]
Liron, T., Raphael, B., Hiram-Bab, S., Bab, I. A., & Gabet, Y. (2018).,Bone loss in C57BL/6J-OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha-synuclein and multimerin-1 genes., Journal of Cellular Physiology, 233(1), 371-377. doi:10.1002/jcp.25895 [doi]
Mahul-Mellier, A. L., Fauvet, B., Gysbers, A., Dikiy, I., Oueslati, A., Georgeon, S., . . . Lashuel, H. A. (2014).,c-abl phosphorylates alpha-synuclein and regulates its degradation: Implication for alpha-synuclein clearance and contribution to the pathogenesis of parkinson's disease., Human Molecular Genetics, 23(11), 2858-2879. doi:10.1093/hmg/ddt674 [doi]
Jonsson, O., Steffen, A. C., Sundquist, V. S., Janson, J., Martinsson, S., Maatta, U., & Emanuelsson, A. B. (2013).,Capillary microsampling and analysis of 4-microl blood, plasma and serum samples to determine human alpha-synuclein elimination rate in mice, Bioanalysis, 5(4), 449-462. doi:10.4155/bio.12.337 [doi]
Weihofen, Andreas; Liu, YuTing; Arndt, Joseph W; Huy, Christian; Quan, Chao; Smith, Benjamin A; Baeriswyl, Jean-Luc; Cavegn, Nicole; Senn, Luzia; Su, Lihe; Marsh, Galina; Auluck, Pavan K; Montrasio, Fabio; Nitsch, Roger M; Hirst, Warren D; Cedarbaum, Jesse M; Pepinsky, R Blake; Grimm, Jan; Weinreb, Paul H,Development of an aggregate-selective, human-derived ?-synuclein-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinsons disease models., Neurobiology of disease Vol.124, 2019
Weihofen, A., Liu, Y., Arndt, J. W., Huy, C., Quan, C., Smith, B. A., . . . Weinreb, P. H. (2018).,Development of an aggregate-selective, human-derived alpha-synuclein antibody BIIB054 that ameliorates disease phenotypes in parkinson's disease models, Neurobiology of Disease, doi:S0969-9961(18)30448-0 [pii]
Pelkonen, A., Kallunki, P., & Yavich, L. (2013),Effects of exogenous alpha-synuclein on stimulated dopamine overflow in dorsal striatum, Neuroscience Letters, 554, 141-145. doi:10.1016/j.neulet.2013.08.072 [doi]
Garcia-Reitboeck, P., Anichtchik, O., Dalley, J. W., Ninkina, N., Tofaris, G. K., Buchman, V. L., & Spillantini, M. G. (2013),Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra., Experimental Neurology, 248, 541-545. doi:10.1016/j.expneurol.2013.07.015 [doi]
Emanuele, M., Esposito, A., Camerini, S., Antonucci, F., Ferrara, S., Seghezza, S., . . . Chieregatti, E. (2016).,Exogenous alpha-synuclein alters pre- and post-synaptic activity by fragmenting lipid rafts., Ebiomedicine, 7, 191-204. doi:10.1016/j.ebiom.2016.03.038 [doi]
Chadchankar, H., Ihalainen, J., Tanila, H., & Yavich, L. (2012).,Methylphenidate modifies overflow and presynaptic compartmentalization of dopamine via an alpha-synuclein-dependent mechanism., The Journal of Pharmacology and Experimental Therapeutics, 341(2), 484-492. doi:10.1124/jpet.111.189225 [doi]
Burtscher J, Copin JC, Sandi C, Lashuel HA.,Pronounced ?-Synuclein Pathology in a Seeding-Based Mouse Model Is Not Sufficient to Induce Mitochondrial Respiration Deficits in the Striatum and Amygdala, eNeuro. 2020 Aug 17;7(4):ENEURO.0110-20.2020. doi: 10.1523/ENEURO.0110-20.2020. Print 2020 Jul/Aug.
Bar, R., Boehm-Cagan, A., Luz, I., Kleper-Wall, Y., & Michaelson, D. M. (2017).,The effects of apolipoprotein E genotype, alpha-synuclein deficiency, and sex on brain synaptic and alzheimer's disease-related pathology, Alzheimer's & Dementia (Amsterdam, Netherlands), 10, 1-11. doi:10.1016/j.dadm.2017.08.003 [doi]

Behavior

Humby, T., Cross, E. S., Messer, L., Guerrero, S., & Davies, W. (2016),A pharmacological mouse model suggests a novel risk pathway for postpartum psychosis., Psychoneuroendocrinology, 74, 363-370. doi:S0306-4530(16)30216-5 [pii]
Janecek, E., Waindok, P., Bankstahl, M., & Strube, C. (2017).,Abnormal neurobehaviour and impaired memory function as a consequence of toxocara canis- as well as toxocara cati-induced neurotoxocarosis., PLoS Neglected Tropical Diseases, 11(5), e0005594. doi:10.1371/journal.pntd.0005594 [doi]
Voikar, V., Krackow, S., Lipp, H. P., Rau, A., Colacicco, G., & Wolfer, D. P. (2018).,Automated dissection of permanent effects of hippocampal or prefrontal lesions on performance at spatial, working memory and circadian timing tasks of C57BL/6 mice in IntelliCage., Behavioural Brain Research, 352, 8-22. doi:S0166-4328(17)30962-2 [pii]
Laricchiuta, D., Musella, A., Rossi, S., & Centonze, D. (2014),Behavioral and electrophysiological effects of endocannabinoid and dopaminergic systems on salient stimuli., Frontiers in Behavioral Neuroscience, 8, 183. doi:10.3389/fnbeh.2014.00183 [doi]
Heinla, I., Ahlgren, J., Vasar, E., & Voikar, V. (2018).,Behavioural characterization of C57BL/6N and BALB/c female mice in social home cage - effect of mixed housing in complex environment., Physiology & Behavior, 188, 32-41. doi:S0031-9384(18)30032-5 [pii]
Laricchiuta, D., Rojo, M. L., Rodriguez-Gaztelumendi, A., Ferlazzo, F., Petrosini, L., & Fowler, C. J. (2012).,CB1 receptor autoradiographic characterization of the individual differences in approach and avoidance motivation, PloS One, 7(7), e42111. doi:10.1371/journal.pone.0042111 [doi]
Noack, J., Murau, R., & Engelmann, M. (2015).,Consequences of temporary inhibition of the medial amygdala on social recognition memory performance in mice, Frontiers in Neuroscience, 9, 152. doi:10.3389/fnins.2015.00152 [doi]
Tam, S. K., Hasan, S., Choi, H. M., Brown, L. A., Jagannath, A., Hughes, S., . . . Peirson, S. N. (2017).,Constant light desynchronizes olfactory versus object and visuospatial recognition memory performance., The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 37(13), 3555-3567. doi:10.1523/JNEUROSCI.3213-16.2017 [doi]
Laricchiuta, D., Rossi, S., Musella, A., De Chiara, V., Cutuli, D., Centonze, D., & Petrosini, L. (2012).,Differences in spontaneously avoiding or approaching mice reflect differences in CB1-mediated signaling of dorsal striatal transmission., PloS One, 7(3), e33260. doi:10.1371/journal.pone.0033260 [doi]
Reichenbach, N., Herrmann, U., Kahne, T., Schicknick, H., Pielot, R., Naumann, M., . . . Tischmeyer, W. (2015).,Differential effects of dopamine signalling on long-term memory formation and consolidation in rodent brain., Proteome Science, 13, 13-015-0069-2. eCollection 2015. doi:10.1186/s12953-015-0069-2 [doi]
Camats-Perna, Judith; Kalaba, Predrag; Ebner, Karl; Sartori, Simone B; Vuyyuru, Harish; Aher, Nilima Y; Draga?evi?, Vladimir; Singewald, Nicolas; Engelmann, Mario; Lubec, Gert;,Differential Effects of Novel Dopamine Reuptake Inhibitors on Interference With Long-Term Social Memory in Mice., Frontiers in behavioral neuroscience Vol.13, 2019
Laricchiuta, D., Centonze, D., & Petrosini, L. (2013).,Effects of endocannabinoid and endovanilloid systems on aversive memory extinction., Behavioural Brain Research, 256, 101-107. doi:10.1016/j.bbr.2013.08.010 [doi]
Labots, M., Zheng, X., Moattari, G., Ohl, F., & van Lith, H. A. (2016).,Effects of light regime and substrain on behavioral profiles of male C57BL/6 mice in three tests of unconditioned anxiety, Journal of Neurogenetics, 30(3-4), 306-315. doi:10.1080/01677063.2016.1249868 [doi]
Ehmer I, Crown L, van Leeuwen W, Feenstra M, Willuhn I, Denys D.,Evidence for Distinct Forms of Compulsivity in the SAPAP3 Mutant-Mouse Model for Obsessive-Compulsive Disorder, eNeuro. 2020 Apr 28;7(2):ENEURO.0245-19.2020. doi: 10.1523/ENEURO.0245-19.2020. Print 2020 Mar/Apr.
de Hoz, L., & Nelken, I. (2014).,Frequency tuning in the behaving mouse: Different bandwidths for discrimination and generalization, PloS One, 9(3), e91676. doi:10.1371/journal.pone.0091676 [doi]
Åhlgren, Johanna; Voikar, Vootele;,Housing mice in the individually ventilated or open cages-Does it matter for behavioral phenotype?, Genes, brain, and behavior Vol.18, 2019
Laricchiuta, D., Saba, L., De Bartolo, P., Caioli, S., Zona, C., & Petrosini, L. (2016),Maintenance of aversive memories shown by fear extinction-impaired phenotypes is associated with increased activity in the amygdaloid-prefrontal circuit., Scientific Reports, 6, 21205. doi:10.1038/srep21205 [doi]
Kulesskaya, N., Karpova, N. N., Ma, L., Tian, L., & Voikar, V. (2014).,Mixed housing with DBA/2 mice induces stress in C57BL/6 mice: Implications for interventions based on social enrichment., Frontiers in Behavioral Neuroscience, 8, 257. doi:10.3389/fnbeh.2014.00257 [doi]
Ahmadlou, M., & Heimel, J. A. (2015).,Preference for concentric orientations in the mouse superior colliculus., Nature Communications, 6, 6773. doi:10.1038/ncomms7773 [doi]
Houben, T., Coomans, C. P., & Meijer, J. H. (2014).,Regulation of circadian and acute activity levels by the murine suprachiasmatic nuclei, PloS One, 9(10), e110172. doi:10.1371/journal.pone.0110172 [doi]
van den Berg, W. E., Lamballais, S., & Kushner, S. A. (2015).,Sex-specific mechanism of social hierarchy in mice., Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 40(6), 1364-1372. doi:10.1038/npp.2014.319 [doi]
Gasser BA, Kurz J, Senn W, Escher G, Mohaupt MG.,Stress-induced alterations of social behavior are reversible by antagonism of steroid hormones in C57/BL6 mice, Naunyn Schmiedebergs Arch Pharmacol. 2021 Jan;394(1):127-135. doi: 10.1007/s00210-020-01970-7. Epub 2020 Sep 7.
Odland, Anna U; Jessen, Lea; Kristensen, Jesper L; Fitzpatrick, Ciarán M; Andreasen, Jesper T;,The 5-hydroxytryptamine 2A receptor agonists DOI and 25CN-NBOH decrease marble burying and reverse 8-OH-DPAT-induced deficit in spontaneous alternation, Neuropharmacology Vol., 2019
O'Brien, F. E., O'Connor, R. M., Clarke, G., Donovan, M. D., Dinan, T. G., Griffin, B. T., & Cryan, J. F. (2014).,The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram., Behavioural Brain Research, 261, 17-25. doi:10.1016/j.bbr.2013.11.027 [doi]
Perna, J. C., Wotjak, C. T., Stork, O., & Engelmann, M. (2015).,Timing of presentation and nature of stimuli determine retroactive interference with social recognition memory in mice., Physiology & Behavior, 143, 10-14. doi:10.1016/j.physbeh.2015.02.029 [doi]

Behavioral and learning disabilities

Kordás K, Kis-Varga Á, Varga A, Eldering H, Bulthuis R, Lendvai B, Lévay G, Román V.,Measuring sociability of mice using a novel three-chamber apparatus and algorithm of the LABORAS™ system, J Neurosci Methods. 2020 Sep 1;343:108841. doi: 10.1016/j.jneumeth.2020.108841. Epub 2020 Jul 1.
Ronda OAHO, van de Heijning BJM, de Bruin A, Thomas RE, Martini I, Koehorst M, Gerding A, Koster MH, Bloks VW, Jurdzinski A, Mulder NL, Havinga R, van der Beek EM, Reijngoud DJ, Kuipers F, Verkade HJ.,Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet, PLoS One. 2020 Sep 21;15(9):e0232069. doi: 10.1371/journal.pone.0232069. eCollection 2020.

Cardiovascular

Gurgen, D., Kusch, A., Klewitz, R., Hoff, U., Catar, R., Hegner, B., . . . Dragun, D. (2013).,Dragun, D. (2013). Sex-specific mTOR signaling determines sexual dimorphism in myocardial adaptation in normotensive DOCA-salt model., Hypertension, 61(3), 730-736. doi:10.1161/HYPERTENSIONAHA.111.00276 [doi]
Case, A. J., Tian, J., & Zimmerman, M. C. (2017).,Increased mitochondrial superoxide in the brain, but not periphery, sensitizes mice to angiotensin II-mediated hypertension., Redox Biology, 11, 82-90. doi:S2213-2317(16)30268-3 [pii]
Tolonen, A. M., Magga, J., Szabo, Z., Viitala, P., Gao, E., Moilanen, A. M., . . . Serpi, R. (2014).,Inhibition of let-7 microRNA attenuates myocardial remodeling and improves cardiac function postinfarction in mice., Pharmacology Research & Perspectives, 2(4), e00056. doi:10.1002/prp2.56 [doi]
Mutikainen, M., Tuomainen, T., Naumenko, N., Huusko, J., Smirin, B., Laidinen, S., . . . Tavi, P. (2016).,Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha1 induces a cardiac excitation-contraction coupling phenotype without metabolic remodelling., The Journal of Physiology, 594(23), 7049-7071. doi:10.1113/JP272847 [doi]
Keijer Hoek-van窝边境,e . F。,J。,Bunschoten,., Vervoort, J. J., Stankova, B., Bekkenkamp, M., . . . van Schothorst, E. M. (2013).,Quercetin induces hepatic lipid omega-oxidation and lowers serum lipid levels in mice., PloS One, 8(1), e51588. doi:10.1371/journal.pone.0051588 [doi]
Guilbeau-Frugier, C., Cauquil, M., Karsenty, C., Lairez, O., Dambrin, C., Payre, B., . . . Gales, C. (2018).,Structural evidence for a new elaborate 3D-organization of the cardiomyocyte lateral membrane in adult mammalian cardiac tissues. Cardiovascular Research, doi:10.1093/cvr/cvy256 [doi], Cardiovascular Research, doi:10.1093/cvr/cvy256 [doi]
Tijsen, A. J., van der Made, I., van den Hoogenhof, M. M., Wijnen, W. J., van Deel, E. D., de Groot, N. E., . . . Creemers, E. E. (2014).,The microRNA-15 family inhibits the TGFbeta-pathway in the heart., Cardiovascular Research, 104(1), 61-71. doi:10.1093/cvr/cvu184 [doi]

COVID-19

Tan T K, Rijal P, Rahikainen R, Keeble A H, Schimanski L, Hussain S, Harvey R, et al.,A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses, bioRxiv 2020.08.31.275701; doi: https://doi.org/10.1101/2020.08.31.275701
Ghebremedhin A, Salam AB, Adu-Addai B, Noonan S, Stratton R, Ahmed MSU, Khantwal C, Martin GR, Lin H, Andrews C, Karanam B, Rudloff U, Lopez H, Jaynes J, Yates C.,A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice, bioRxiv. 2020 Jul 29:2020.07.27.218115. doi: 10.1101/2020.07.27.218115. Preprint.
Schumann S, Kaiser A, Nicoletti F, Mangano K, Fagone P, van Wijk E, Yan Y, Schulz P, Ludescher B, Niedermaier M, von Wegerer J, Rauch P, Setz C, Schubert U, Brysch W.,Immune-Modulating Drug MP1032 with SARS-CoV-2 Antiviral Activity In Vitro: A potential Multi-Target Approach for Prevention and Early Intervention Treatment of COVID-19, Int J Mol Sci. 2020 Nov 20;21(22):8803. doi: 10.3390/ijms21228803.
Stanelle-Bertram, S., Schaumburg, B., Kouassi, N. M., Beck, S., Zickler, M., Beythien, G., ... & dos Reis, V. P.,SARS-CoV-2 induced CYP19A1 expression in the lung correlates with increased aromatization of testosterone-to-estradiol in male golden hamsters, Research Square, 20 Nov 2020. DOI: 10.21203/rs.3.rs-107474/v1
Singh V, Beer A, Kraus A, et al.,Stroke increases the expression of ACE2, the SARS-CoV-2 binding receptor, in murine lungs, bioRxiv 2020.06.24.162941; doi: https://doi.org/10.1101/2020.06.24.162941
Ye G, Gallant JP, Massey C, Shi K, Tai W, Zheng J, Odle AE, Vickers MA, Shang J, Wan Y, Drelich A, Kempaiah KR, Tat V, Perlman S, Du L, Tseng CT, Aihara H, LeBeau AM, Li F.,The Development of a Novel Nanobody Therapeutic for SARS-CoV-2, bioRxiv. 2020 Nov 17:2020.11.17.386532. doi: 10.1101/2020.11.17.386532. Preprint.

Diabetes type 2

Roesti ES, Boyle CN, Zeman DT, Sande-Melon M, Storni F, Cabral-Miranda G, Knuth A, Lutz TA, Vogel M, Bachmann MF.,Vaccination Against Amyloidogenic Aggregates in Pancreatic Islets Prevents Development of Type 2 Diabetes Mellitus, Vaccines (Basel). 2020 Mar 2;8(1):116. doi: 10.3390/vaccines8010116.

Diet induced obesity

Umek, Nejc; Horvat, Simon; Cvetko, Erika; Kreft, Marko; Janá?ek, Ji?í ; Kubínová, Lucie; Stopar Pintari?, Tatjana; Eržen, Ida;,3D analysis of capillary network in skeletal muscle of obese insulin-resistant mice., Histochemistry and cell biology Vol.152, 2019
Duivenvoorde, L. P., van Schothorst, E. M., Swarts, H. M., Kuda, O., Steenbergh, E., Termeulen, S., . . . Keijer, J. (2015),A difference in fatty acid composition of isocaloric high-fat diets alters metabolic flexibility in male C57BL/6JOlaHsd mice., PloS One, 10(6), e0128515. doi:10.1371/journal.pone.0128515 [doi]
Fernéndez-Calleja, José M S; Bouwman, Lianne M S; Swarts, Hans J M; Billecke, Nils; Oosting, Annemarie; Keijer, Jaap; van Schothorst, Evert M,A Lowly Digestible-Starch Diet after Weaning Enhances Exogenous Glucose Oxidation Rate in Female, but Not in Male, Mice., Nutrients Vol.11, 2019
Eljaafari, A., Robert, M., Chehimi, M., Chanon, S., Durand, C., Vial, G., . . . Pirola, L. (2015),Adipose tissue-derived stem cells from obese subjects contribute to inflammation and reduced insulin response in adipocytes through differential regulation of the Th1/Th17 balance and monocyte activation., Diabetes, 64(7), 2477-2488. doi:10.2337/db15-0162 [doi]
McPherson, N. O., Lane, M., Sandeman, L., Owens, J. A., & Fullston, T. (2017).,An exercise-only intervention in obese fathers restores glucose and insulin regulation in conjunction with the rescue of pancreatic islet cell morphology and MicroRNA expression in male offspring., Nutrients, 9(2), 10.3390/nu9020122. doi:E122 [pii]
Parra-Vargas, M., Sandoval-Rodriguez, A., Rodriguez-Echevarria, R., Dominguez-Rosales, J. A., Santos-Garcia, A., & Armendariz-Borunda, J. (2018).,花翠素改善肝甘油三酯accumulation in human HepG2 cells, but not in diet-induced obese mice., Nutrients, 10(8), 10.3390/nu10081060. doi:E1060 [pii]
Hoek-van den Hil, E. F., van Schothorst, E. M., van der Stelt, I., Swarts, H. J., van Vliet, M., Amolo, T., . . . Keijer, J. (2015),Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice., Genes & Nutrition, 10(4), 469-015-0469-z. Epub 2015 May 29. doi:10.1007/s12263-015-0469-z [doi]
Shi, W., Hegeman, M. A., van Dartel, D. A. M., Tang, J., Suarez, M., Swarts, H., . . . Keijer, J. (2017).,Effects of a wide range of dietary nicotinamide riboside (NR) concentrations on metabolic flexibility and white adipose tissue (WAT) of mice fed a mildly obesogenic diet., Molecular Nutrition & Food Research, 61(8), 10.1002/mnfr.201600878. Epub 2017 Apr 13. doi:10.1002/mnfr.201600878 [doi]
Lombardo, G. E., Lepore, S. M., Morittu, V. M., Arcidiacono, B., Colica, C., Procopio, A., . . . Celano, M. (2018).,Effects of oleacein on high-fat diet-dependent steatosis, weight gain, and insulin resistance in mice., Frontiers in Endocrinology, 9, 116. doi:10.3389/fendo.2018.00116 [doi]
Villalpando-Arteaga, E. V., Mendieta-Condado, E., Esquivel-Solis, H., Canales-Aguirre, A. A., Galvez-Gastelum, F. J., Mateos-Diaz, J. C., . . . Marquez-Aguirre, A. L. (2013).,Hibiscus sabdariffa L. aqueous extract attenuates hepatic steatosis through down-regulation of PPAR-gamma and SREBP-1c in diet-induced obese mice., Food & Function, 4(4), 618-626. doi:10.1039/c3fo30270a [doi]
Shi, Wenbiao; Hegeman, Maria A; Doncheva, Atanaska; Bekkenkamp-Grovenstein, Melissa; de Boer, Vincent C J; Keijer, Jaap;,High Dose of Dietary Nicotinamide Riboside Induces Glucose Intolerance and White Adipose Tissue Dysfunction in Mice Fed a Mildly Obesogenic Diet, Nutrients Vol.11, 2019
Kothari, V., Luo, Y., Tornabene, T., O'Neill, A. M., Greene, M. W., Geetha, T., & Babu, J. R. (2017).,High fat diet induces brain insulin resistance and cognitive impairment in mice. Biochimica Et Biophysica Acta, Molecular Basis of Disease, 1863(2), 499-508. doi:S0925-4439(16)30250-2 [pii]
Vial, G., Chauvin, M. A., Bendridi, N., Durand, A., Meugnier, E., Madec, A. M., . . . Rieusset, J. (2015).,Imeglimin normalizes glucose tolerance and insulin sensitivity and improves mitochondrial function in liver of a high-fat, high-sucrose diet mice model., Diabetes, 64(6), 2254-2264. doi:10.2337/db14-1220 [doi]
Khan, I. M., Perrard, X. Y., Brunner, G., Lui, H., Sparks, L. M., Smith, S. R., . . . Ballantyne, C. M. (2015).,Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance, International Journal of Obesity (2005), 39(11), 1607-1618. doi:10.1038/ijo.2015.104 [doi]
Hermier, Dominique; Lan, Annaïg; Tellier, Frédérique; Blais, Anne; Culetto, Marta Grauso; Mathé, Véronique; Bellec, Yannick; Gissot, Lionel; Schmidely, Philippe; Faure, Jean-Denis;,Intestinal Availability and Metabolic Effects of Dietary Camelina Sphingolipids during the Metabolic Syndrome Onset in Mice, Journal of agricultural and food chemistry Vol.5, 2020
van der Stelt, I., Hoevenaars, F., Siroka, J., de Ronde, L., Friedecky, D., Keijer, J., & van Schothorst, E. (2017),Metabolic response of visceral white adipose tissue of obese mice exposed for 5 days to human room temperature compared to mouse thermoneutrality., Frontiers in Physiology, 8, 179. doi:10.3389/fphys.2017.00179 [doi]
负责人Derous, D, T, van Schothorst e . M。范Erk, M., Voigt, A., Klaus, S., . . . Radonjic, M. (2015).,Network-based integration of molecular and physiological data elucidates regulatory mechanisms underlying adaptation to high-fat diet., Genes & Nutrition, 10(4), 470-015-0470-6. Epub 2015 May 28. doi:10.1007/s12263-015-0470-6 [doi]
Bouwman, L. M. S., Fernandez-Calleja, J. M. S., Swarts, H. J. M., van der Stelt, I., Oosting, A., Keijer, J., & van Schothorst, E. M. (2018),No adverse programming by post-weaning dietary fructose of body weight, adiposity, glucose tolerance, or metabolic flexibility., Molecular Nutrition & Food Research, 62(2), 10.1002/mnfr.201700315. Epub 2017 Dec 11. doi:10.1002/mnfr.201700315 [doi]
Lombardo, G. E., Arcidiacono, B., De Rose, R. F., Lepore, S. M., Costa, N., Montalcini, T., . . . Celano, M. (2016).,Normocaloric diet restores weight gain and insulin sensitivity in obese mice., Frontiers in Endocrinology, 7, 49. doi:10.3389/fendo.2016.00049 [doi]
Donkers, Joanne M; Kooijman, Sander; Slijepcevic, Davor; Kunst, Roni F; Roscam Abbing, Reinout Lp; Haazen, Lizette; de Waart, Dirk R; Levels, Johannes Hm; Schoonjans, Kristina; Rensen, Patrick Cn; Oude Elferink, Ronald Pj; van de Graaf, Stan Fj;,NTCP deficiency in mice protects against obesity and hepatosteatosis., JCI insight Vol.5, 2019
Lepore, Saverio Massimo; Maggisano, Valentina; Bulotta, Stefania; Mignogna, Chiara; Arcidiacono, Biagio; Procopio, Antonio; Brunetti, Antonio; Russo, Diego; Celano, Marilena,Oleacein Prevents High Fat Diet-Induced Adiposity and Ameliorates Some Biochemical Parameters of Insulin Sensitivity in Mice, Nutrients Vol.11, 2019
Jurrissen, Thomas J; Grunewald, Zachary I; Woodford, Makenzie L; Winn, Nathan C; Ball, James R; Smith, Thomas N; Wheeler, Andrew A; Rawlings, Arthur L; Staveley-OCarroll, Kevin F; Ji, Yan; Fay, William P; Paradis, Pierre; Schiffrin, Ernesto L; Vieira-Potter, Victoria J; Fadel, Paul J; Martinez-Lemus, Luis A; Padilla, Jaume;,Overproduction of endothelin-1 impairs glucose tolerance but does not promote visceral adipose tissue inflammation or limit metabolic adaptations to exercise., American journal of physiology. Endocrinology and metabolism Vol.317, 2019
Duivenvoorde, L. P., van Schothorst, E. M., Derous, D., van der Stelt, I., Masania, J., Rabbani, N., . . . Keijer, J. (2015).,Oxygen restriction as challenge test reveals early high-fat-diet-induced changes in glucose and lipid metabolism., Pflugers Archiv : European Journal of Physiology, 467(6), 1179-1193. doi:10.1007/s00424-014-1553-8 [doi]
Dhandapani, Praveen K; Lyyski, Annina M; Paulin, Lars; Khan, Nahid A; Suomalainen, Anu; Auvinen, Petri; Dufour, Eric; Szibor, Marten; Jacobs, Howard T;,Phenotypic effects of dietary stress in combination with a respiratory chain bypass in mice, Physiological reports Vol.7, 2019
Ronda, Onne A H O; van de Heijning, Bert J M; de Bruin, Alain; Jurdzinski, Angelika; Kuipers, Folkert; Verkade, Henkjan J;,Programming effects of an early life diet containing large phospholipid-coated lipid globules are transient under continuous exposure to a high-fat diet, The British journal of nutrition Vol.122, 2019
Gutman, Roee; Rauch, Maayan; Neuman, Annat; Khamaisi, Hazem; Jonas-Levi, Adi; Konovalova, Yelena; Rytwo, Giora;,Sepiolite Clay Attenuates the Development of Hypercholesterolemia and Obesity in Mice Fed a High-Fat High-Cholesterol Diet., Journal of medicinal food Vol.5, 2019
Voigt, A., Agnew, K., van Schothorst, E. M., Keijer, J., & Klaus, S. (2013).,Short-term, high fat feeding-induced changes in white adipose tissue gene expression are highly predictive for long-term changes., Molecular Nutrition & Food Research, 57(8), 1423-1434. doi:10.1002/mnfr.201200671 [doi]
Fullston, T., Ohlsson-Teague, E. M., Print, C. G., Sandeman, L. Y., & Lane, M. (2016).,Sperm microRNA content is altered in a mouse model of male obesity, but the same suite of microRNAs are not altered in offspring's sperm., PloS One, 11(11), e0166076. doi:10.1371/journal.pone.0166076 [doi]
Pisani, D. F., Ghandour, R. A., Beranger, G. E., Le Faouder, P., Chambard, J. C., Giroud, M., . . . Amri, E. Z. (2014).,The omega6-fatty acid, arachidonic acid, regulates the conversion of white to brite adipocyte through a prostaglandin/calcium mediated pathway., Molecular Metabolism, 3(9), 834-847. doi:10.1016/j.molmet.2014.09.003 [doi]
Bekkenkamp-Grovenstein Hoevenaars, f P, M, 1月ssen, R. J., Heil, S. G., Bunschoten, A., Hoek-van den Hil, E. F., . . . Keijer, J. (2014).,Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences, Molecular Nutrition & Food Research, 58(4), 799-807. doi:10.1002/mnfr.201300285 [doi]
Shi, Wenbiao; Hegeman, Maria A; Doncheva, Atanaska; van der Stelt, Inge; Bekkenkamp-Grovenstein, Melissa; van Schothorst, Evert M; Brenner, Charles; de Boer, Vincent C J; Keijer, Jaap;,Transcriptional Response of White Adipose Tissue to Withdrawal of Vitamin B3、分子营养与食品研究Vol.11, 2019
Hoevenaars, Femke P M; Keijer, Jaap; van der Stelt, Inge; Duivenvoorde, Loes P M; Herreman, Laure; van Nes, Robin; Friedecký, David; Hegeman, Maria A; van Schothorst, Evert M;,White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality: Response Markers Identified, but no WAT Inflammation., Genes Vol.10, 2019

General studies

Moore, Scott Emory; Voss, Joachim G; St Pierre Schneider, Barbara;,17?-estradiol alters mRNA co-expression after murine muscle injury and mild hypobaria.实验生物学和医学(新泽西州梅伍德) Vol.244, 2019
Sajic, Tatjana; Ciuffa, Rodolfo; Lemos, Vera; Xu, Pan; Leone, Valentina; Li, Chen; Williams, Evan G; Makris, Georgios; Banaei-Esfahani, Amir; Heikenwalder, Mathias; Schoonjans, Kristina; Aebersold, Ruedi;,A new class of protein biomarkers based on subcellular distribution: application to a mouse liver cancer model., Scientific reports Vol.9, 2019
Wenborn, A., Terry, C., Gros, N., Joiner, S., D'Castro, L., Panico, S., . . . Wadsworth, J. D. (2015).,A novel and rapid method for obtaining high titre intact prion strains from mammalian brain., Scientific Reports, 5, 10062. doi:10.1038/srep10062 [doi]
van de Moosdijk AAA, van de Grift YBC, de Man SMA, Zeeman AL, van Amerongen R.,A novel Axin2 knock-in mouse model for visualization and lineage tracing of WNT/CTNNB1 responsive cells, Genesis. 2020 Sep;58(9):e23387. doi: 10.1002/dvg.23387. Epub 2020 Jul 9.
Gomez-Pinilla, P. J., Binda, M. M., Lissens, A., Di Giovangiulio, M., van Bree, S. H., Nemethova, A., . . . Boeckxstaens, G. E. (2014),没有肠道炎症和postoperative ileus in a mouse model of laparoscopic surgery., Neurogastroenterology and Motility : The Official Journal of the European Gastrointestinal Motility Society, 26(9), 1238-1247. doi:10.1111/nmo.12376 [doi]
Lohuis, Mirjam A M; Werkman, Cornelieke C N; Harmsen, Hermie J M; Tietge, Uwe J F; Verkade, Henkjan J;,Absence of Intestinal Microbiota during Gestation and Lactation Does Not Alter the Metabolic Response to a Western-type Diet in Adulthood., Molecular nutrition & food research Vol.63, 2019
Hemmatian, H., Laurent, M. R., Ghazanfari, S., Vanderschueren, D., Bakker, A. D., Klein-Nulend, J., & van Lenthe, G. H. (2017).,Accuracy and reproducibility of mouse cortical bone microporosity as quantified by desktop microcomputed tomography., PloS One, 12(8), e0182996. doi:10.1371/journal.pone.0182996 [doi
Korte SW, Dorfmeyer RA, Franklin CL, Ericsson AC.,Acute and long-term effects of antibiotics commonly used in laboratory animal medicine on the fecal microbiota, Vet Res. 2020 Sep 14;51(1):116. doi: 10.1186/s13567-020-00839-0.
Hunter, R. W., Craigie, E., Homer, N. Z., Mullins, J. J., & Bailey, M. A. (2014).,Acute inhibition of NCC does not activate distal electrogenic na+ reabsorption or kaliuresis., American Journal of Physiology.Renal Physiology, 306(4), F457-67. doi:10.1152/ajprenal.00339.2013 [doi]
Gross CM, Kovacs-Kasa A, Meadows ML, Cherian-Shaw M, Fulton DJ, Verin AD.,Adenosine and ATP?S protect against bacterial pneumonia-induced acute lung injury, Sci Rep. 2020 Oct 22;10(1):18078. doi: 10.1038/s41598-020-75224-0.
Hoevenaars, F. P., Keijer, J., Herreman, L., Palm, I., Hegeman, M. A., Swarts, H. J., & van Schothorst, E. M. (2014).,Adipose tissue metabolism and inflammation are differently affected by weight loss in obese mice due to either a high-fat diet restriction or change to a low-fat diet., Genes & Nutrition, 9(3), 391-014-0391-9. Epub 2014 Apr 10. doi:10.1007/s12263-014-0391-9 [doi]
Green, Lisa J; Zhou, Hong; Padmanabhan, Vasantha; Shikanov, Ariella;,Adipose-derived stem cells promote survival, growth, and maturation of early-stage murine follicles., Stem cell research & therapy Vol.10, 2019
Hodges EL, Marshall JP, Ashpole NM.,Age-dependent hormesis-like effects of the synthetic cannabinoid CP55940 in C57BL/6 mice, NPJ Aging Mech Dis. 2020 Jul 6;6:7. doi: 10.1038/s41514-020-0045-7. eCollection 2020.
Long, D. A., Kolatsi-Joannou, M., Price, K. L., Dessapt-Baradez, C., Huang, J. L., Papakrivopoulou, E., . . . Woolf, A. S. (2013).,Albuminuria is associated with too few glomeruli and too much testosterone., Kidney International, 83(6), 1118-1129. doi:10.1038/ki.2013.45 [doi]
Faustini, Gaia; Marchesan, Elena; Zonta, Laura; Bono, Federica; Bottani, Emanuela; Longhena, Francesca; Ziviani, Elena; Valerio, Alessandra; Bellucci, Arianna,Alpha-Synuclein Preserves Mitochondrial Fusion and Function in Neuronal Cells., Oxidative medicine and cellular longevity Vol.2019, 2019
Dawson, N., M. Kurihara, D.M. Thomson, C.L. Winchester, A. McVie, J.R. Hedde, A.D. Randall, S. Shen, P.A. Seymour, Z.A. Hughes, J. Dunlop, J.T. Brown, N.J. Brandon, B.J. Morris, and J.A. Pratt. 2015.,Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated Disrupted-in-Schizophrenia 1., Transl.Psychiatry. 5:e569.
Huo, Y., Win, S., Than, T. A., Yin, S., Ye, M., Hu, H., & Kaplowitz, N. (2017),Antcin H protects against acute liver injury through disruption of the interaction of c-jun-N-terminal kinase with mitochondria., Antioxidants & Redox Signaling, 26(5), 207-220. doi:10.1089/ars.2016.6833 [doi]
Schwaerzer, Gerburg K; Kalyanaraman, Hema; Casteel, Darren E; Dalton, Nancy D; Gu, Yusu; Lee, Seunghoe; Zhuang, Shunhui; Wahwah, Nisreen; Schilling, Jan M; Patel, Hemal H; Zhang, Qian; Makino, Ayako; Milewicz, Dianna M; Peterson, Kirk L; Boss, Gerry R; Pilz, Renate B,Aortic pathology from protein kinase G activation is prevented by an antioxidant vitamin B12 analog., Nature communications Vol.10, 2019
Gordon, Bradley S; Rossetti, Michael L; Eroshkin, Alexey M;,Arrdc2 and Arrdc3 elicit divergent changes in gene expression in skeletal muscle following anabolic and catabolic stimuli., Physiological genomics Vol.51, 2019
Lerner, Shaul; Anderzhanova, Elmira; Verbitsky, Sima; Eilam, Raya; Kuperman, Yael; Tsoory, Michael; Kuznetsov, Yuri; Brandis, Alexander; Mehlman, Tevie; Mazkereth, Ram; McCarter, Robert; Segal, Menahem; Nagamani, Sandesh C S; Chen, Alon; Erez, Ayelet,ASL Metabolically Regulates Tyrosine Hydroxylase in the Nucleus Locus Coeruleus., Cell reports Vol.29, 2019
Chakrabarti, Sudipta; Roy, Avik; Prorok, Tim; Patel, Dhruv; Dasarathi, Sridevi; Pahan, Kalipada;,Aspirin up-regulates suppressor of cytokine signaling 3 in glial cells via PPAR?, Journal of neurochemistry Vol.151, 2019
Landolt, Lea; Furriol, Jessica; Babickova, Janka; Ahmed, Lavina; Eikrem, Øystein; Skogstrand, Trude; Scherer, Andreas; Suliman, Salwa; Leh, Sabine; Lorens, James B; Gausdal, Gro; Marti, Hans-Peter; Osman, Tarig,AXL targeting reduces fibrosis development in experimental unilateral ureteral obstruction, Physiological reports Vol.7, 2019
Hoevenaars, F. P., van Schothorst, E. M., Horakova, O., Voigt, A., Rossmeisl, M., Pico, C., . . . Keijer, J. (2012),BIOCLAIMS standard diet (BIOsd): A reference diet for nutritional physiology., Genes & Nutrition, 7(3), 399-404. doi:10.1007/s12263-011-0262-6 [doi]
Hoevenaars, F.P., E.M. van Schothorst, O. Horakova, A. Voigt, M. Rossmeisl, C. Pico, A. Caimari, J. Kopecky, S. Klaus, and J. Keijer. 2012.,BIOCLAIMS standard diet (BIOsd): a reference diet for nutritional physiology., Genes Nutr. 7:399-404.
Palm, I. F., Schram, R. G. A. E., Swarts, H. J. M., van Schothorst, E. M., & Keijer, J. (2017).,Body weight cycling with identical diet composition does not affect energy balance and has no adverse effect on metabolic health parameters, Nutrients, 9(10), 10.3390/nu9101149. doi:E1149 [pii]
Chrobok, N. L., Bol, J. G. J. M., Jongenelen, C. A., Breve, J. J. P., El Alaoui, S., Wilhelmus, M. M. M., . . . van Dam, A. M. (2018).,Characterization of transglutaminase 2 activity inhibitors in monocytes in vitro and their effect in a mouse model for multiple sclerosis, PloS One, 13(4), e0196433. doi:10.1371/journal.pone.0196433 [doi]
Stalinska, J; Zimolag, E; Pianovich, N A; Zapata, A; Lassak, A; Rak, M; Dean, M; Ucar-Bilyeu, D; Wyczechowska, D; Culicchia, F; Marrero, L; Del Valle, L; Sarkaria, J; Peruzzi, F; Jursic, B S; Reiss, K;,Chemically Modified Variants of Fenofibrate with Antiglioblastoma Potential., Translational oncology Vol.12, 2019
Silvennoinen, R., Quesada, H., Kareinen, I., Julve, J., Kaipiainen, L., Gylling, H., . . . Lee-Rueckert, M. (2015),Chronic intermittent psychological stress promotes macrophage reverse cholesterol transport by impairing bile acid absorption in mice., Physiological Reports, 3(5), 10.14814/phy2.12402. doi:10.14814/phy2.12402 [doi]
O'Brien, F. E., Moloney, G. M., Scott, K. A., O'Connor, R. M., Clarke, G., Dinan, T. G., . . . Cryan, J. F. (2015).,Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: Potential implications for treating depression., Pharmacology Research & Perspectives, 3(6), e00190. doi:10.1002/prp2.190 [doi]
Win, S., Than, T. A., Min, R. W., Aghajan, M., & Kaplowitz, N. (2016),c-jun N-terminal kinase mediates mouse liver injury through a novel sab (SH3BP5)-dependent pathway leading to inactivation of intramitochondrial src, Hepatology (Baltimore, Md.), 63(6), 1987-2003. doi:10.1002/hep.28486 [doi
Bedussi, B., van Lier, M. G., Bartstra, J. W., de Vos, J., Siebes, M., VanBavel, E., & Bakker, E. N. (2015),Clearance from the mouse brain by convection of interstitial fluid towards the ventricular system., Fluids and Barriers of the CNS, 12, 23-015-0019-5. doi:10.1186/s12987-015-0019-5 [doi]
Derdelinckx, Judith; Mansilla, María Josè; De Laere, Maxime; Lee, Wai-Ping; Navarro-Barriuso, Juan; Wens, Inez; Nkansah, Irene; Daans, Jasmijn; De Reu, Hans; Jolanta Keliris, Aneta; Van Audekerke, Johan; Vanreusel, Verdi; Pieters, Zoë; Van der Linden, Annemie; Verhoye, Marleen; Molenberghs, Geert; Hens, Niel; Goossens, Herman; Willekens, Barbara; Cras, Patrick; Ponsaerts, Peter; Berneman, Zwi N; Martínez-Cáceres, Eva María; Cools, Nathalie;,Clinical and immunological control of experimental autoimmune encephalomyelitis by tolerogenic dendritic cells loaded with MOG-encoding mRNA., Journal of neuroinflammation Vol.16, 2019
DiGruccio, M. R., Mawla, A. M., Donaldson, C. J., Noguchi, G. M., Vaughan, J., Cowing-Zitron, C., . . . Huising, M. O. (2016).,Comprehensive alpha, beta and delta cell transcriptomes reveal that ghrelin selectively activates delta cells and promotes somatostatin release from pancreatic islets., Molecular Metabolism, 5(7), 449-458. doi:S2212-8778(16)30031-X [pii]
Kohtala, S., Theilmann, W., Rosenholm, M., Penna, L., Karabulut, G., Uusitalo, S., . . . Rantamaki, T. (2018).,Cortical excitability and activation of TrkB signaling during rebound slow oscillations are critical for rapid antidepressant responses., Molecular Neurobiology, doi:10.1007/s12035-018-1364-6 [doi]
Beckermann TM, Welch RC, Williams FM, Mortlock DP, Sha F, Ikizler TA, Woodard LE, Wilson MH.,CRISPR/Cas9 engineering of albino cystinuria Type A mice, Genesis. 2020 May;58(5):e23357. doi: 10.1002/dvg.23357. Epub 2020 Feb 20.
Rosenblum D, Gutkin A, Kedmi R, Ramishetti S, Veiga N, Jacobi AM, Schubert MS, Friedmann-Morvinski D, Cohen ZR, Behlke MA, Lieberman J, Peer D.,CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy, Sci Adv. 2020 Nov 18;6(47):eabc9450. doi: 10.1126/sciadv.abc9450. Print 2020 Nov.
Blauer, M., Sand, J., & Laukkarinen, J. (2013).,Cryopreserved mouse pancreatic acinar cells from long-term explant outgrowth cultures maintain their secretory phenotype after thawing., Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ...[Et Al.], 13(6), 610-614. doi:10.1016/j.pan.2013.09.006 [doi]
Srn, L. E., Hammarberg, L. K., Kastenmayer, R. J., & Hallengren, L. C. (2016),Developing a performance standard for adequate sanitization of wire-bar lids., Journal of the American Association for Laboratory Animal Science : JAALAS, 55(6), 765-768.
Westerkamp, A. C., Pully, V. V., Karimian, G., Bomfati, F., Veldhuis, Z. J., Wiersema-Buist, J., . . . Porte, R. J. (2015).,Diffuse reflectance spectroscopy accurately quantifies various degrees of liver steatosis in murine models of fatty liver disease., Journal of Translational Medicine, 13, 309-015-0671-1. doi:10.1186/s12967-015-0671-1 [doi]
Hoek-van den Hil, E. F., van Schothorst, E. M., van der Stelt, I., Swarts, H. J., van Vliet, M., Amolo, T., . . . Keijer, J. (2015),Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice., Genes & Nutrition, 10(4), 469-015-0469-z. Epub 2015 May 29. doi:10.1007/s12263-015-0469-z [doi]
Rossetti, Michael L; Esser, Karyn A; Lee, Choogon; Tomko, Robert J; Eroshkin, Alexey M; Gordon, Bradley S;,Disruptions to the limb muscle core molecular clock coincide with changes in mitochondrial quality control following androgen depletion., American journal of physiology. Endocrinology and metabolism Vol.317, 2019
Patel, R., Baker, S. S., Liu, W., Desai, S., Alkhouri, R., Kozielski, R., . . . Zhu, L. (2012).,Effect of dietary advanced glycation end products on mouse liver., PloS One, 7(4), e35143. doi:10.1371/journal.pone.0035143 [doi]
Gardner, L. B., Hori, T., Chen, F., Baine, A. M., Hata, T., Uemoto, S., & Nguyen, J. H. (2012),Effect of specific activation of gamma-aminobutyric acid receptor in vivo on oxidative stress-induced damage after extended hepatectomy., Hepatology Research : The Official Journal of the Japan Society of Hepatology, 42(11), 1131-1140. doi:10.1111/j.1872-034X.2012.01030.x [doi]
Horn, M. J., Hudson, S. V., Bostrom, L. A., & Cooper, D. M. (2012),Effects of cage density, sanitation frequency, and bedding type on animal wellbeing and health and cage environment in mice and rats., Journal of the American Association for Laboratory Animal Science : JAALAS, 51(6), 781-788.
Panagiotou, Maria; Meijer, Mandy; Meijer, Johanna H; Deboer, Tom;,Effects of chronic caffeine consumption on sleep and the sleep electroencephalogram in mice., Journal of psychopharmacology (Oxford, England) Vol.29, 2018
Panagiotou, M; Deboer, T;,Effects of Chronic Dim-light-at-night Exposure on Sleep in Young and Aged Mice, Neuroscience Vol.426, 2020
Hoevenaars, F. P., Keijer, J., Swarts, H. J., Snaas-Alders, S., Bekkenkamp-Grovenstein, M., & van Schothorst, E. M. (2013),Effects of dietary history on energy metabolism and physiological parameters in C57BL/6J mice., Experimental Physiology, 98(5), 1053-1062. doi:10.1113/expphysiol.2012.069518 [doi]
Dudley, E. S., Johnson, R. A., French, D. C., & Boivin, G. P. (2016),Effects of topical anesthetics on behavior, plasma corticosterone, and blood glucose levels after tail biopsy of C57BL/6NHSD mice (mus musculus)., Journal of the American Association for Laboratory Animal Science : JAALAS, 55(4), 443-450.
Xu, W., Jones, M., Liu, B., Zhu, X., Johnson, C. B., Edwards, A. C., . . . Wong, H. C. (2013),Efficacy and mechanism-of-action of a novel superagonist interleukin-15: Interleukin-15 receptor alphaSu/Fc fusion complex in syngeneic murine models of multiple myeloma., Cancer Research, 73(10), 3075-3086. doi:10.1158/0008-5472.CAN-12-2357 [doi]
Velazquez, Eric M; Nguyen, Henry; Heasley, Keaton T; Saechao, Cheng H; Gil, Lindsey M; Rogers, Andrew W L; Miller, Brittany M; Rolston, Matthew R; Lopez, Christopher A; Litvak, Yael; Liou, Megan J; Faber, Franziska; Bronner, Denise N; Tiffany, Connor R; Byndloss, Mariana X; Byndloss, Austin J; Bäumler, Andreas J,Endogenous Enterobacteriaceae underlie variation in susceptibility to Salmonella infection., Nature microbiology Vol.4, 2019
Kareinen, I., Cedo, L., Silvennoinen, R., Laurila, P. P., Jauhiainen, M., Julve, J., . . . Lee-Rueckert, M. (2015),Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice, Journal of Lipid Research, 56(2), 241-253. doi:10.1194/jlr.M050948 [doi]
Smith EP, Cotto-Rosario A, Borghesan E, Held K, Miller CN, Celli J.,Epistatic Interplay between Type IV Secretion Effectors Engages the Small GTPase Rab2 in the Brucella Intracellular Cycle, mBio. 2020 Mar 31;11(2):e03350-19. doi: 10.1128/mBio.03350-19.
Pigni, M., Ashok, D., Stevanin, M., & Acha-Orbea, H. (2018).,Establishment and characterization of a functionally competent type 2 conventional dendritic cell line., Frontiers in Immunology, 9, 1912. doi:10.3389/fimmu.2018.01912 [doi]
Conner, K. P., Rock, B. M., Kwon, G. K., Balthasar, J. P., Abuqayyas, L., Wienkers, L. C., & Rock, D. A. (2014).,Evaluation of near infrared fluorescent labeling of monoclonal antibodies as a tool for tissue distribution, Drug Metabolism and Disposition: The Biological Fate of Chemicals, 42(11), 1906-1913. doi:10.1124/dmd.114.060319 [doi]
Khajuria, D. K., Raygorodskaya, M., Kobyliansky, E., Gabet, Y., Hiram Bab, S., Shochat, C., . . . Karasik, D. (2018),Evaluation of the long-term skeletal effect induced by teratogen 5-aza-2'deoxycytidine on offspring of high (C3H/HeJ) and low (C57BL/6J) bone mass phenotype mice, Bone Reports, 8, 239-243. doi:10.1016/j.bonr.2018.05.005 [doi]
Win, Sanda; Min, Robert Wm; Chen, Christopher Q; Zhang, Jun; Chen, Yibu; Li, Meng; Suzuki, Ayako; Abdelmalek, Manal F; Wang, Ying; Aghajan, Mariam; Aung, Filbert Wm; Diehl, Anna Mae; Davis, Roger J; Than, Tin A; Kaplowitz, Neil;,Expression of mitochondrial membrane-linked SAB determines severity of sex-dependent acute liver injury., The Journal of clinical investigation Vol.129, 2019
Steinzeig, Anna; Cannarozzo, Cecilia; Castrén, Eero,Fluoxetine-induced plasticity in the visual cortex outlasts the duration of the naturally occurring critical period, The European journal of neuroscience Vol.50, 2019
Hata, Toshiyuki; Rehman, Fatima; Hori, Tomohide; Nguyen, Justin H;,GABA, ?-Aminobutyric Acid, Protects Against Severe Liver Injury., The Journal of surgical research Vol.236, 2019
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Resnik, Nataša; Erman, Andreja; Verani?, Peter; Kreft, Mateja Erdani;,Triple labelling of actin filaments, intermediate filaments and microtubules for broad application in cell biology: uncovering the cytoskeletal composition in tunneling nanotubes, Histochemistry and cell biology Vol.152, 2019
Duale N, Eide DM, Amberger ML, Graupner A, Brede DA, Olsen AK.,Using prediction models to identify miRNA-based markers of low dose rate chronic stress, Sci Total Environ. 2020 May 15;717:137068. doi: 10.1016/j.scitotenv.2020.137068. Epub 2020 Feb 4.
Wolf, Yochai; Bartok, Osnat; Patkar, Sushant; Eli, Gitit Bar; Cohen, Sapir; Litchfield, Kevin; Levy, Ronen; Jiménez-Sánchez, Alejandro; Trabish, Sophie; Lee, Joo Sang; Karathia, Hiren; Barnea, Eilon; Day, Chi-Ping; Cinnamon, Einat; Stein, Ilan; Solomon, Adam; Bitton, Lital; Pérez-Guijarro, Eva; Dubovik, Tania; Shen-Orr, Shai S; Miller, Martin L; Merlino, Glenn; Levin, Yishai; Pikarsky, Eli; Eisenbach, Lea; Admon, Arie; Swanton, Charles; Ruppin, Eytan; Samuels, Yardena;,UVB-Induced Tumor Heterogeneity Diminishes Immune Response in Melanoma, Cell Vol.179, 2019
Tsai, P. P., Nagelschmidt, N., Kirchner, J., Stelzer, H. D., & Hackbarth, H. (2012).,Validation of an automatic system (DoubleCage) for detecting the location of animals during preference tests., Laboratory Animals, 46(1), 81-84. doi:10.1258/la.2011.011072 [doi]
Karimian, G., Kirschbaum, M., Veldhuis, Z. J., Bomfati, F., Porte, R. J., & Lisman, T. (2015).,Vitamin E attenuates the progression of non-alcoholic fatty liver disease caused by partial hepatectomy in mice, PloS One, 10(11), e0143121. doi:10.1371/journal.pone.0143121 [doi]
Bläuer, Merja; Laaninen, Matias; Sand, Juhani; Laukkarinen, Johanna;,Wnt/?-catenin signalling plays diverse functions during the process of fibrotic remodelling in the exocrine pancreas., Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] Vol.19, 2019

Genetically modified

Kohler, C., Dinekov, M., & Gotz, J. (2013).,活跃的糖原合成酶激酶3和τpathology-related tyrosine phosphorylation in pR5 human tau transgenic mice., Neurobiology of Aging, 34(5), 1369-1379. doi:10.1016/j.neurobiolaging.2012.11.010 [doi]
Ataca, D., Caikovski, M., Piersigilli, A., Moulin, A., Benarafa, C., Earp, S. E., . . . Brisken, C. (2016).,Adamts18 deletion results in distinct developmental defects and provides a model for congenital disorders of lens, lung, and female reproductive tract development, Biology Open, 5(11), 1585-1594. doi:10.1242/bio.019711 [doi]
Dawson, N., Kurihara, M., Thomson, D. M., Winchester, C. L., McVie, A., Hedde, J. R., . . . Pratt, J. A. (2015).,Altered functional brain network connectivity and glutamate system function in transgenic mice expressing truncated disrupted-in-schizophrenia 1, Translational Psychiatry, 5, e569. doi:10.1038/tp.2015.60 [doi]
Nasser, A., Moller, L. B., Olesen, J. H., Konradsen, L. S., & Andreasen, J. T. (2014).,Anxiety- and depression-like phenotype of hph-1 mice deficient in tetrahydrobiopterin, Neuroscience Research, 89, 44-53. doi:10.1016/j.neures.2014.08.015 [doi]
Marino, M., Papa, S., Crippa, V., Nardo, G., Peviani, M., Cheroni, C., . . . Bendotti, C. (2015).,Differences in protein quality control correlate with phenotype variability in 2 mouse models of familial amyotrophic lateral sclerosis, Neurobiology of Aging, 36(1), 492-504. doi:10.1016/j.neurobiolaging.2014.06.026 [doi]
Grimm, C., Chavez, L., Vilardell, M., Farrall, A. L., Tierling, S., Bohm, J. W., . . . Morkel, M. (2013).,DNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancer., PLoS Genetics, 9(2), e1003250. doi:10.1371/journal.pgen.1003250 [doi]
Dupont, C., Loos, F., Kong-A-San, J., & Gribnau, J. (2017).,FGF treatment of host embryos injected with ES cells increases rates of chimaerism., Transgenic Research, 26(2), 237-246. doi:10.1007/s11248-016-9997-6 [doi]
Zhou, Y. S., Ihmoda, I. A., Phelps, R. G., Bellamy, C. O., & Turner, A. N. (2015).,Following specific podocyte injury captopril protects against progressive long term renal damage., F1000research, 4, 172. doi:10.12688/f1000research.4030.1 [doi]
Munoz-Ballester, C., Berthier, A., Viana, R., & Sanz, P. (2016),星形谷氨酸内在的体内平衡r GLT-1 is altered in mouse models of lafora disease, Biochimica Et Biophysica Acta, 1862(6), 1074-1083. doi:10.1016/j.bbadis.2016.03.008 [doi]
Fagnan A, Bagger FO, Piqué-Borràs MR, Ignacimouttou C, Caulier A, Lopez CK, Robert E, Uzan B, Gelsi-Boyer V, Aid Z, Thirant C, Moll U, Tauchmann S, Kurtovic-Kozaric A, Maciejewski J, Dierks C, Spinelli O, Salmoiraghi S, Pabst T, Shimoda K, Deleuze V, Lapillonne H, Sweeney C, De Mas V, Leite B, Kadri Z, Malinge S, de Botton S, Micol JB, Kile B, Carmichael CL, Iacobucci I, Mullighan CG, Carroll M, Valent P, Bernard OA, Delabesse E, Vyas P, Birnbaum D, Anguita E, Garçon L, Soler E, Schwaller J, Mercher T.,Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers, Blood. 2020 Aug 6;136(6):698-714. doi: 10.1182/blood.2019003062.
Rygh, C. B., Lokka, G., Heljasvaara, R., Taxt, T., Pavlin, T., Sormunen, R., . . . Reed, R. K. (2014).,Image-based assessment of microvascular function and structure in collagen XV- and XVIII-deficient mice, The Journal of Physiology, 592(Pt 2), 325-336. doi:10.1113/jphysiol.2013.263574 [doi]
Viana Lopez-Gonzalez,我,R, Sanz, P, &费雷尔I. (2017).,Inflammation in lafora disease: Evolution with disease progression in laforin and malin knock-out mouse models., Molecular Neurobiology, 54(5), 3119-3130. doi:10.1007/s12035-016-9884-4 [doi]
Marriott, H. M., Gascoyne, K. A., Gowda, R., Geary, I., Nicklin, M. J., Iannelli, F., . . . Dockrell, D. H. (2012).,Interleukin-1beta regulates CXCL8 release and influences disease outcome in response to streptococcus pneumoniae, defining intercellular cooperation between pulmonary epithelial cells and macrophages., Infection and Immunity, 80(3), 1140-1149. doi:10.1128/IAI.05697-11 [doi]
Tortarolo, M., Vallarola, A., Lidonnici, D., Battaglia, E., Gensano, F., Spaltro, G., . . . Bendotti, C. (2015).,Lack of TNF-alpha receptor type 2 protects motor neurons in a cellular model of amyotrophic lateral sclerosis and in mutant SOD1 mice but does not affect disease progression, Journal of Neurochemistry, 135(1), 109-124. doi:10.1111/jnc.13154 [doi]
Voikar, V., Kulesskaya, N., Laakso, T., Lauren, J., Strittmatter, S. M., & Airaksinen, M. S. (2013),LRRTM1-deficient mice show a rare phenotype of avoiding small enclosures--a tentative mouse model for claustrophobia-like behaviour., Behavioural Brain Research, 238, 69-78. doi:10.1016/j.bbr.2012.10.013 [doi]
Shen, H., Hyrc, K. L., & Goldberg, M. P. (2013),Maintaining energy homeostasis is an essential component of wld(S)-mediated axon protection., Neurobiology of Disease, 59, 69-79. doi:10.1016/j.nbd.2013.07.007 [doi]
Salminen, A. V., Garrett, L., Schormair, B., Rozman, J., Giesert, F., Niedermeier, K. M., . . . Winkelmann, J. (2017).,Meis1: Effects on motor phenotypes and the sensorimotor system in mice., Disease Models & Mechanisms, 10(8), 981-991. doi:10.1242/dmm.030080 [doi]
Kondo, S., Bottos, A., Allegood, J. C., Masson, R., Maurer, F. G., Genoud, C., . . . Hynes, N. E. (2014).,Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development, PloS One, 9(4), e94114. doi:10.1371/journal.pone.0094114 [doi]
Frank, E., Wu, Y., Piyaratna, N., Body, W. J., Snikeris, P., South, T., . . . Huang, X. F. (2012).,Metabolic parameters and emotionality are little affected in G-protein coupled receptor 12 (Gpr12) mutant mice, PloS One, 7(8), e42395. doi:10.1371/journal.pone.0042395 [doi]
Pasetto, L., Olivari, D., Nardo, G., Trolese, M. C., Bendotti, C., Piccirillo, R., & Bonetto, V. (2018),Micro-computed tomography for non-invasive evaluation of muscle atrophy in mouse models of disease., PloS One, 13(5), e0198089. doi:10.1371/journal.pone.0198089 [doi]
Booth, C. A., Brown, J. T., & Randall, A. D. (2014).,Neurophysiological modification of CA1 pyramidal neurons in a transgenic mouse expressing a truncated form of disrupted-in-schizophrenia 1., The European Journal of Neuroscience, 39(7), 1074-1090. doi:10.1111/ejn.12549 [doi]
Mizrachi, T., Brill, L., Rabie, M., Nevo, Y., Fellig, Y., Zur, M., . . . Vaknin-Dembinsky, A. (2018).,NMO-IgG and AQP4 peptide can induce aggravation of EAMG and immune-mediated muscle weakness., Journal of Immunology Research, 2018, 5389282. doi:10.1155/2018/5389282 [doi]
Hellsten, K. S., Linden, A. M., & Korpi, E. R. (2015).,Paradoxical widespread c-fos expression induced by a GABA agonist in the forebrain of transgenic mice with ectopic expression of the GABA(A) alpha6 subunit., Neuroscience, 293, 123-135. doi:10.1016/j.neuroscience.2015.02.052 [doi]
Berthier, A., Paya, M., Garcia-Cabrero, A. M., Ballester, M. I., Heredia, M., Serratosa, J. M., . . . Sanz, P. (2015),Pharmacological interventions to ameliorate neuropathological symptoms in a mouse model of lafora disease, Molecular Neurobiology, doi:10.1007/s12035-015-9091-8 [doi]
Berthier, A., Paya, M., Garcia-Cabrero, A. M., Ballester, M. I., Heredia, M., Serratosa, J. M., . . . Sanz, P. (2016),Pharmacological interventions to ameliorate neuropathological symptoms in a mouse model of lafora disease., Molecular Neurobiology, 53(2), 1296-1309. doi:10.1007/s12035-015-9091-8 [doi]
Svarcbahs, Reinis; Jäntti, Maria; Kilpeläinen, Tommi; Julku, Ulrika H; Urvas, Lauri; Kivioja, Saara; Norrbacka, Susanna; Myöhänen, Timo T;,Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A, Pharmacological research Vol.151, 2019
Mahajan, V. S., Demissie, E., Mattoo, H., Viswanadham, V., Varki, A., Morris, R., & Pillai, S. (2016).,Striking immune phenotypes in gene-targeted mice are driven by a copy-number variant originating from a commercially available C57BL/6 strain., Cell Reports, 15(9), 1901-1909. doi:10.1016/j.celrep.2016.04.080 [doi]
Galliano, E., Potters, J. W., Elgersma, Y., Wisden, W., Kushner, S. A., De Zeeuw, C. I., & Hoebeek, F. E. (2013),Synaptic transmission and plasticity at inputs to murine cerebellar purkinje cells are largely dispensable for standard nonmotor tasks., The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 33(31), 12599-12618. doi:10.1523/JNEUROSCI.1642-13.2013 [doi]
Montero-Barrera, D., Valderrama-Carvajal, H., Terrazas, C. A., Rojas-Hernandez, S., Ledesma-Soto, Y., Vera-Arias, L., . . . Terrazas, L. I. (2015).,The macrophage galactose-type lectin-1 (MGL1) recognizes taenia crassiceps antigens, triggers intracellular signaling, and is critical for resistance to this infection., BioMed Research International, 2015, 615865. doi:10.1155/2015/615865 [doi]
Kool, M. J., van de Bree, J. E., Bodde, H. E., Elgersma, Y., & van Woerden, G. M. (2016).,The molecular, temporal and region-specific requirements of the beta isoform of Calcium/Calmodulin-dependent protein kinase type 2 (CAMK2B) in mouse locomotion., Scientific Reports, 6, 26989. doi:10.1038/srep26989 [doi]
Aumailley, L., Roux-Dalvai, F., Kelly, I., Droit, A., & Lebel, M. (2018).,Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional werner syndrome (wrn) mutant protein., PloS One, 13(3), e0193170. doi:10.1371/journal.pone.0193170 [doi]

Immunology

Kim, Sang-Soo; Harford, Joe B; Moghe, Manish; Slaughter, Tiffani; Doherty, Caroline; Chang, Esther H;,肿瘤纳米药物携带p53通用电气ne crosses the blood-brain barrier and enhances anti-PD-1 immunotherapy in mouse models of glioblastoma., International journal of cancer Vol.145, 2019
Narra, H. P., Shubitz, L. F., Mandel, M. A., Trinh, H. T., Griffin, K., Buntzman, A. S., . . . Orbach, M. J. (2016).,A coccidioides posadasii CPS1 deletion mutant is avirulent and protects mice from lethal infection., Infection and Immunity, 84(10), 3007-3016. doi:10.1128/IAI.00633-16 [doi]
El-Kenawi Asmaa;Gatenbee,钱德勒;Robertson-Tessi, Mark; Bravo, Rafael; Dhillon, Jasreman; Balagurunathan, Yoganand; Berglund, Anders; Vishvakarma, Naveen; Ibrahim-Hashim, Arig; Choi, Jung; Luddy, Kimberly; Gatenby, Robert; Pilon-Thomas, Shari; Anderson, Alexander; Ruffell, Brian; Gillies, Robert,Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer., British journal of cancer Vol.121, 2019
Koutsoumpli, Georgia; Ip, Peng Peng; Schepel, Ilona; Hoogeboom, Baukje Nynke; Boerma, Annemarie; Daemen, Toos;,Alphavirus-based hepatitis C virus therapeutic vaccines: can universal helper epitopes enhance HCV-specific cytotoxic T lymphocyte responses?, Therapeutic advances in vaccines and immunotherapy Vol.7, 2019
Ip, P. P., Boerma, A., Regts, J., Meijerhof, T., Wilschut, J., Nijman, H. W., & Daemen, T. (2014).,Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses., Molecular Therapy : The Journal of the American Society of Gene Therapy, 22(4), 881-890. doi:10.1038/mt.2013.287 [doi]
Starkey Lewis P, Campana L, Aleksieva N, Cartwright JA, Mackinnon A, O'Duibhir E, Kendall T, Vermeren M, Thomson A, Gadd V, Dwyer B, Aird R, Man TY, Rossi AG, Forrester L, Park BK, Forbes SJ.,Alternatively activated macrophages promote resolution of necrosis following acute liver injury, J Hepatol. 2020 Aug;73(2):349-360. doi: 10.1016/j.jhep.2020.02.031. Epub 2020 Mar 11.
Kolomansky A, Kaye I, Ben-Califa N, Gorodov A, Awida Z, Sadovnic O, Ibrahim M, Liron T, Hiram-Bab S, Oster HS, Sarid N, Perry C, Gabet Y, Mittelman M, Neumann D.,Anti-CD20-Mediated B Cell Depletion Is Associated With Bone Preservation in Lymphoma Patients and Bone Mass Increase in Mice, Front Immunol. 2020 Oct 19;11:561294. doi: 10.3389/fimmu.2020.561294. eCollection 2020.
Ip, P. P., Boerma, A., Walczak, M., Oosterhuis, K., Haanen, J. B., Schumacher, T. N., . . . Daemen, T. (2015),Antigen design enhances the immunogenicity of semliki forest virus-based therapeutic human papillomavirus vaccines, Gene Therapy, 22(7), 560-567. doi:10.1038/gt.2015.24 [doi]
Le, T. T., Karmouty-Quintana, H., Melicoff, E., Le, T. T., Weng, T., Chen, N. Y., . . . Blackburn, M. R. (2014),Blockade of IL-6 trans signaling attenuates pulmonary fibrosis., Journal of Immunology (Baltimore, Md.: 1950), 193(7), 3755-3768. doi:10.4049/jimmunol.1302470 [doi]
Veiga-Parga, T., Gimenez, F., Mulik, S., Chiang, E. Y., Grogan, J. L., & Rouse, B. T. (2013).,Controlling herpetic stromal keratitis by modulating lymphotoxin-alpha-mediated inflammatory pathways., Microbes and Infection / Institut Pasteur, 15(10-11), 677-687. doi:10.1016/j.micinf.2013.07.001 [doi]
Curato, Caterina; Bernshtein, Biana; Zupanci?, Eva; Dufner, Almut; Jaitin, Diego; Giladi, Amir; David, Eyal; Chappell-Maor, Louise; Leshkowitz, Dena; Knobeloch, Klaus-Peter; Amit, Ido; Florindo, Helena F; Jung, Steffen,DC Respond to Cognate T Cell Interaction in the Antigen-Challenged Lymph Node., Frontiers in immunology Vol.10, 2019
Travers, Meghan; Brown, Stephen M; Dunworth, Matthew; Holbert, Cassandra E; Wiehagen, Karla R; Bachman, Kurtis E; Foley, Jackson R; Stone, Meredith L; Baylin, Stephen B; Casero, Robert A; Zahnow, Cynthia A;,DFMO and 5-Azacytidine Increase M1 Macrophages in the Tumor Microenvironment of Murine Ovarian Cancer., Cancer research Vol.79, 2019
Pujol Lopez, Y., Kenis, G., Stettinger, W., Neumeier, K., de Jonge, S., Steinbusch, H. W., . . . Myint, A. M. (2016).,Effects of prenatal poly I:C exposure on global histone deacetylase (HDAC) and DNA methyltransferase (DNMT) activity in the mouse brain., Molecular Biology Reports, 43(7), 711-717. doi:10.1007/s11033-016-4006-y [doi]
Spencer, A. J., Cottingham, M. G., Jenks, J. A., Longley, R. J., Capone, S., Colloca, S., . . . Hill, A. V. (2014).,Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain., PloS One, 9(6), e100538. doi:10.1371/journal.pone.0100538 [doi]
Myhill LJ, Stolzenbach S, Mejer H, Jakobsen SR, Hansen TVA, Andersen D, Brix S, Hansen LH, Krych L, Nielsen DS, Nejsum P, Thamsborg SM, Williams AR.,Fermentable Dietary Fiber Promotes Helminth Infection and Exacerbates Host Inflammatory Responses, J Immunol. 2020 Jun 1;204(11):3042-3055. doi: 10.4049/jimmunol.1901149. Epub 2020 Apr 13.
Timmermans, S., Bogie, J. F., Vanmierlo, T., Lutjohann, D., Stinissen, P., Hellings, N., & Hendriks, J. J. (2014).,High fat diet exacerbates neuroinflammation in an animal model of multiple sclerosis by activation of the renin angiotensin system., Journal of Neuroimmune Pharmacology : The Official Journal of the Society on NeuroImmune Pharmacology, 9(2), 209-217. doi:10.1007/s11481-013-9502-4 [doi]
Xiao, L., Leusink-Muis, T., Kettelarij, N., van Ark, I., Blijenberg, B., Hesen, N. A., . . . Van't Land, B. (2018).,Human milk oligosaccharide 2'-fucosyllactose improves innate and adaptive immunity in an influenza-specific murine vaccination model., Frontiers in Immunology, 9, 452. doi:10.3389/fimmu.2018.00452 [doi]
Joshi, Shrinidh; Wollenzien, Hannah; Leclerc, Estelle; Jarajapu, Yagna Pr;,Hypoxic regulation of angiotensin-converting enzyme 2 and Mas receptor in human CD34+ cells., Journal of cellular physiology Vol.234, 2019
Sharma-Chawla, Niharika; Stegemann-Koniszewski, Sabine; Christen, Henrike; Boehme, Julia D; Kershaw, Olivia; Schreiber, Jens; Guzmán, Carlos A; Bruder, Dunja; Hernandez-Vargas, Esteban A;,In vivo Neutralization of Pro-inflammatory Cytokines During Secondary Streptococcus pneumoniae Infection Post Influenza A Virus Infection., Frontiers in immunology Vol.10, 2019
Mastelic Gavillet, B., Eberhardt, C. S., Auderset, F., Castellino, F., Seubert, A., Tregoning, J. S., . . . Siegrist, C. A. (2015).,MF59 mediates its B cell adjuvanticity by promoting T follicular helper cells and thus germinal center responses in adult and early life., Journal of Immunology (Baltimore, Md.: 1950), 194(10), 4836-4845. doi:10.4049/jimmunol.1402071 [doi]
Mastelic Gavillet, B., Eberhardt, C. S., Auderset, F., Castellino, F., Seubert, A., Tregoning, J. S., . . . Siegrist, C. A. (2015).,MF59 mediates its B cell adjuvanticity by promoting T follicular helper cells and thus germinal center responses in adult and early life., Journal of Immunology (Baltimore, Md.: 1950), 194(10), 4836-4845. doi:10.4049/jimmunol.1402071 [doi]
Insua, J. L., Llobet, E., Moranta, D., Perez-Gutierrez, C., Tomas, A., Garmendia, J., & Bengoechea, J. A. (2013).,Modeling klebsiella pneumoniae pathogenesis by infection of the wax moth galleria mellonella., Infection and Immunity, 81(10), 3552-3565. doi:10.1128/IAI.00391-13 [doi]
Dong, W., Bhide, Y., Marsman, S., Holtrop, M., Meijerhof, T., de Vries-Idema, J., . . . Huckriede, A. (2018).,Monophosphoryl lipid A-adjuvanted virosomes with ni-chelating lipids for attachment of conserved viral proteins as cross-protective influenza vaccine., Biotechnology Journal, 13(4), e1700645. doi:10.1002/biot.201700645 [doi]
Fenninger, Franz; Han, Jeffrey; Stanwood, Shawna R; Nohara, Lilian L; Arora, Hitesh; Choi, Kyung Bok; Munro, Lonna; Pfeifer, Cheryl G; Shanina, Iryna; Horwitz, Marc S; Jefferies, Wilfred A;,Mutation of an L-Type Calcium Channel Gene Leads to T Lymphocyte Dysfunction., Frontiers in immunology Vol.10, 2019
Marín, María Q; Pérez, Patricia; Ljungberg, Karl; Sorzano, Carlos Óscar S; Gómez, Carmen E; Liljeström, Peter; Esteban, Mariano; García-Arriaza, Juan;,Potent Anti-hepatitis C Virus (HCV) T Cell Immune Responses Induced in Mice Vaccinated with DNA-Launched RNA Replicons and Modified Vaccinia Virus Ankara-HCV, Journal of virology Vol.93, 2019
Jaligama, S., Saravia, J., You, D., Yadav, N., Lee, G. I., Shrestha, B., & Cormier, S. A. (2017).,Regulatory T cells and IL10 suppress pulmonary host defense during early-life exposure to radical containing combustion derived ultrafine particulate matter., Respiratory Research, 18(1), 15-016-0487-4. doi:10.1186/s12931-016-0487-4 [doi]
Krueger, Caroline C; Thoms, Franziska; Keller, Elsbeth; Leoratti, Fabiana M S; Vogel, Monique; Bachmann, Martin F;,RNA and Toll-Like Receptor 7 License the Generation of Superior Secondary Plasma Cells at Multiple Levels in a B Cell Intrinsic Fashion, Frontiers in immunology Vol.10, 2019
3月,C,可以o, V., Moranta, D., Llobet, E., Perez-Gutierrez, C., Tomas, J. M., . . . Bengoechea, J. A. (2013),Role of bacterial surface structures on the interaction of klebsiella pneumoniae with phagocytes, PloS One, 8(2), e56847. doi:10.1371/journal.pone.0056847 [doi]
Jensen, S. E., Illigen, K. E., Badsberg, J. H., & Haslov, K. R. (2012).,Specificity and detection limit of a dermal temperature histamine sensitization test for absence of residual pertussis toxin in vaccines., Biologicals : Journal of the International Association of Biological Standardization, 40(1), 36-40. doi:10.1016/j.biologicals.2011.09.015 [doi]
Yamamoto, Atsushi; Hester, Joanna; Macklin, Philip S; Kawai, Kento; Uchiyama, Masateru; Biggs, Daniel; Bishop, Tammie; Bull, Katherine; Cheng, Xiaotong; Cawthorne, Eleanor; Coleman, Mathew L; Crockford, Tanya L; Davies, Ben; Dow, Lukas E; Goldin, Rob; Kranc, Kamil; Kudo, Hiromi; Lawson, Hannah; McAuliffe, James; Milward, Kate; Scudamore, Cheryl L; Soilleux, Elizabeth; Issa, Fadi; Ratcliffe, Peter J; Pugh, Chris W;,Systemic silencing of PHD2 causes reversible immune regulatory dysfunction., The Journal of clinical investigation Vol.130, 2019
Tuku B, Stanelle-Bertram S, Sellau J, Beck S, Bai T, Kouassi NM, Preuß A, Hoenow S, Renné T, Lotter H, Gabriel G.,Testosterone Protects Against Severe Influenza by Reducing the Pro-Inflammatory Cytokine Response in the Murine Lung, Front Immunol. 2020 Apr 22;11:697. doi: 10.3389/fimmu.2020.00697. eCollection 2020.
Worth AA, Shoop R, Tye K, Feetham CH, D'Agostino G, Dodd GT, Reimann F, Gribble FM, Beebe EC, Dunbar JD, Alexander-Chacko JT, Sindelar DK, Coskun T, Emmerson PJ, Luckman SM.,The cytokine GDF15 signals through a population of brainstem cholecystokinin neurons to mediate anorectic signalling, Elife. 2020 Jul 29;9:e55164. doi: 10.7554/eLife.55164.
van Schaik, E. J., Case, E. D., Martinez, E., Bonazzi, M., & Samuel, J. E. (2017),The SCID mouse model for identifying virulence determinants in coxiella burnetii., Frontiers in Cellular and Infection Microbiology, 7, 25. doi:10.3389/fcimb.2017.00025 [doi]
许·希普利FB,达尼N, H, C自然神论者,崔J, JP, Sadegh C, Fame RM, Shannon ML, Flores VI, Kishkovich T, Jang E, Klein EM, Goldey GJ, He K, Zhang Y, Holtzman MJ, Kirchhausen T, Wyart C, Moore CI, Andermann ML, Lehtinen MK.,Tracking Calcium Dynamics and Immune Surveillance at the Choroid Plexus Blood-Cerebrospinal Fluid Interface, Neuron. 2020 Nov 25;108(4):623-639.e10. doi: 10.1016/j.neuron.2020.08.024. Epub 2020 Sep 21.
Detje, C. N., Lienenklaus, S., Chhatbar, C., Spanier, J., Prajeeth, C. K., Soldner, C., . . . Kalinke, U. (2015).,Upon intranasal vesicular stomatitis virus infection, astrocytes in the olfactory bulb are important interferon beta producers that protect from lethal encephalitis.病毒学杂志》,89(5),2731 - 2738。doi: 10.1128/JVI.02044-14 [doi]
Krueger, Caroline C; Thoms, Franziska; Keller, Elsbeth; Vogel, Monique; Bachmann, Martin F;,Virus-Specific Secondary Plasma Cells Produce Elevated Levels of High-Avidity Antibodies but Are Functionally Short Lived, Frontiers in immunology Vol.10, 2019
Cimica V, Williams S, Adams-Fish D, McMahon C, Narayanan A, Rashid S, Stedman TT.,Zika Virus-Like Particle (VLP) vaccine displaying Envelope (E) protein CD loop antigen elicits protective and specific immune response in a murine model, Biochem Biophys Res Commun. 2020 Aug 27;529(3):805-811. doi: 10.1016/j.bbrc.2020.05.161. Epub 2020 Jul 20.

Infectious disease

Tan T K, Rijal P, Rahikainen R, Keeble A H, Schimanski L, Hussain S, Harvey R, et al.,A COVID-19 vaccine candidate using SpyCatcher multimerization of the SARS-CoV-2 spike protein receptor-binding domain induces potent neutralising antibody responses, bioRxiv 2020.08.31.275701; doi: https://doi.org/10.1101/2020.08.31.275701
Ghebremedhin A, Salam AB, Adu-Addai B, Noonan S, Stratton R, Ahmed MSU, Khantwal C, Martin GR, Lin H, Andrews C, Karanam B, Rudloff U, Lopez H, Jaynes J, Yates C.,A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice, bioRxiv. 2020 Jul 29:2020.07.27.218115. doi: 10.1101/2020.07.27.218115. Preprint.
Schumann S, Kaiser A, Nicoletti F, Mangano K, Fagone P, van Wijk E, Yan Y, Schulz P, Ludescher B, Niedermaier M, von Wegerer J, Rauch P, Setz C, Schubert U, Brysch W.,Immune-Modulating Drug MP1032 with SARS-CoV-2 Antiviral Activity In Vitro: A potential Multi-Target Approach for Prevention and Early Intervention Treatment of COVID-19, Int J Mol Sci. 2020 Nov 20;21(22):8803. doi: 10.3390/ijms21228803.
Stanelle-Bertram, S., Schaumburg, B., Kouassi, N. M., Beck, S., Zickler, M., Beythien, G., ... & dos Reis, V. P.,SARS-CoV-2 induced CYP19A1 expression in the lung correlates with increased aromatization of testosterone-to-estradiol in male golden hamsters, Research Square, 20 Nov 2020. DOI: 10.21203/rs.3.rs-107474/v1
Singh V, Beer A, Kraus A, et al.,Stroke increases the expression of ACE2, the SARS-CoV-2 binding receptor, in murine lungs, bioRxiv 2020.06.24.162941; doi: https://doi.org/10.1101/2020.06.24.162941
Ye G, Gallant JP, Massey C, Shi K, Tai W, Zheng J, Odle AE, Vickers MA, Shang J, Wan Y, Drelich A, Kempaiah KR, Tat V, Perlman S, Du L, Tseng CT, Aihara H, LeBeau AM, Li F.,The Development of a Novel Nanobody Therapeutic for SARS-CoV-2, bioRxiv. 2020 Nov 17:2020.11.17.386532. doi: 10.1101/2020.11.17.386532. Preprint.

Neuroscience

Myohanen, T. T., Hannula, M. J., Van Elzen, R., Gerard, M., Van Der Veken, P., Garcia-Horsman, J. A., . . . Lambeir, A. M. (2012),A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of parkinson's disease., British Journal of Pharmacology, 166(3), 1097-1113. doi:10.1111/j.1476-5381.2012.01846.x [doi]
Myohanen, T.T., M.J. Hannula, R. Van Elzen, M. Gerard, P. Van Der Veken, J.A. Garcia-Horsman, V. Baekelandt, P.T. Mannisto, and A.M. Lambeir. 2012.,A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease., Br.J.Pharmacol. 166:1097-1113.
Van Zandt, M; Weiss, E; Almyasheva, A; Lipior, S; Maisel, S; Naegele, J R;,Adeno-associated viral overexpression of neuroligin 2 in the mouse hippocampus enhances GABAergic synapses and impairs hippocampal-dependent behaviors., Behavioural brain research Vol.362, 2019
Navarria, L., Zaltieri, M., Longhena, F., Spillantini, M. G., Missale, C., Spano, P., & Bellucci, A. (2015).,Alpha-synuclein modulates NR2B-containing NMDA receptors and decreases their levels after rotenone exposure., Neurochemistry International, 85-86, 14-23. doi:10.1016/j.neuint.2015.03.008 [doi]
Kangas, S. M., Ohlmeier, S., Sormunen, R., Jouhilahti, E. M., Peltonen, S., Peltonen, J., & Heape, A. M. (2016).,An approach to comprehensive genome and proteome expression analyses in schwann cells and neurons during peripheral nerve myelin formation., Journal of Neurochemistry, 138(6), 830-844. doi:10.1111/jnc.13722 [doi]
Mahul-Mellier, A. L., Fauvet, B., Gysbers, A., Dikiy, I., Oueslati, A., Georgeon, S., . . . Lashuel, H. A. (2014).,c-abl phosphorylates alpha-synuclein and regulates its degradation: Implication for alpha-synuclein clearance and contribution to the pathogenesis of parkinson's disease, Human Molecular Genetics, 23(11), 2858-2879. doi:10.1093/hmg/ddt674 [doi]
Mahul-Mellier, A.L., B. Fauvet, A. Gysbers, I. Dikiy, A. Oueslati, S. Georgeon, A.J. Lamontanara, A. Bisquertt, D. Eliezer, E. Masliah, G. Halliday, O. Hantschel, and H.A. Lashuel. 2014.,c-Abl phosphorylates alpha-synuclein and regulates its degradation: implication for alpha-synuclein clearance and contribution to the pathogenesis of Parkinson's disease., Hum.Mol.Genet. 23:2858-2879.
de Groot, M. W., Dingemans, M. M., Rus, K. H., de Groot, A., & Westerink, R. H. (2014).,Characterization of calcium responses and electrical activity in differentiating mouse neural progenitor cells in vitro, Toxicological Sciences : An Official Journal of the Society of Toxicology, 137(2), 428-435. doi:10.1093/toxsci/kft261 [doi]
Yamada, Y., & Prosser, R. A. (2014).,Copper chelation and exogenous copper affect circadian clock phase resetting in the suprachiasmatic nucleus in vitro., Neuroscience, 256, 252-261. doi:10.1016/j.neuroscience.2013.10.033 [doi]
Shen, H., & Goldberg, M. P. (2012).,Creatine pretreatment protects cortical axons from energy depletion in vitro, Neurobiology of Disease, 47(2), 184-193. doi:10.1016/j.nbd.2012.03.037 [doi]
Herranen A, Ikäheimo K, Lankinen T, Pakarinen E, Fritzsch B, Saarma M, Lindahl M, Pirvola U.,Deficiency of the ER-stress-regulator MANF triggers progressive outer hair cell death and hearing loss, Cell Death Dis. 2020 Feb 6;11(2):100. doi: 10.1038/s41419-020-2286-6.
Forsgard, R. A., Korpela, R., Stenman, L. K., Osterlund, P., & Holma, R. (2014),Deoxycholic acid induced changes in electrophysiological parameters and macromolecular permeability in murine small intestine with and without functional enteric nervous system plexuses., Neurogastroenterology and Motility : The Official Journal of the European Gastrointestinal Motility Society, 26(8), 1179-1187. doi:10.1111/nmo.12383 [doi]
Bolkvadze, T & Pitkanen a .(2012)。Development of post-traumatic epilepsy after controlled cortical impact and lateral fluid-percussion-induced brain injury in the mouse., Journal of Neurotrauma, 29(5), 789-812. doi:10.1089/neu.2011.1954 [doi]
Gorberg V, McCaffery P, Anavi-Goffer S.,Different responses of repetitive behaviours in juvenile and young adult mice to Δ9‐tetrahydrocannabinol and cannabidiol may affect decision making for Tourette syndrome, Br J Pharmacol. 2021 Feb;178(3):614-625. doi: 10.1111/bph.15302. Epub 2020 Dec 2.
Wiebelhaus, J. M., Vunck, S. A., Meltzer, H. Y., & Porter, J. H. (2012).,Discriminative stimulus properties of N-desmethylclozapine, the major active metabolite of the atypical antipsychotic clozapine, in C57BL/6 mice., Behavioural Pharmacology, 23(3), 262-270. doi:10.1097/FBP.0b013e3283534332 [doi]
Goltstein, P. M., Montijn, J. S., & Pennartz, C. M. (2015).,在乐团patte异氟烷麻醉的影响rns of Ca2+ activity in mouse v1: Reduced direction selectivity independent of increased correlations in cellular activity., PloS One, 10(2), e0118277. doi:10.1371/journal.pone.0118277 [doi]
Lopez, Y. P., Steinbusch, H. W., Rutten, B., Kenis, G., van den Hove, D. L., & Myint, A. M. (2015).,Effects of subcutaneous LPS injection on gestational length and intrauterine and neonatal mortality in mice., Neuroimmunomodulation, 22(4), 274-278. doi:10.1159/000368554 [doi]
Lopez, Y.P., H.W. Steinbusch, B. Rutten, G. Kenis, D.L. van den Hove, and A.M. Myint. 2015.,Effects of subcutaneous LPS injection on gestational length and intrauterine and neonatal mortality in mice., Neuroimmunomodulation. 22:274-278.
Schulz, Jan M; Knoflach, Frederic; Hernandez, Maria-Clemencia; Bischofberger, Josef; Enhanced Dendritic Inhibition and Impaired NMDAR Activation in a Mouse Model of Down Syndrome,Enhanced Dendritic Inhibition and Impaired NMDAR Activation in a Mouse Model of Down Syndrome., The Journal of neuroscience : the official journal of the Society for Neuroscience Vol.39, 2019
Su, C., Sun, F., Cunningham, R. L., Rybalchenko, N., & Singh, M. (2014),ERK5/KLF4 signaling as a common mediator of the neuroprotective effects of both nerve growth factor and hydrogen peroxide preconditioning., Age (Dordrecht, Netherlands), 36(4), 9685-014-9685-5. Epub 2014 Jul 12. doi:10.1007/s11357-014-9685-5 [doi]
Eakin, K., Li, Y., Chiang, Y. H., Hoffer, B. J., Rosenheim, H., Greig, N. H., & Miller, J. P. (2013).,Exendin-4 ameliorates traumatic brain injury-induced cognitive impairment in rats, PloS One, 8(12), e82016. doi:10.1371/journal.pone.0082016 [doi]
Eakin, K., Y. Li, Y.H. Chiang, B.J. Hoffer, H. Rosenheim, N.H. Greig, and J.P. Miller. 2013.,Exendin-4 ameliorates traumatic brain injury-induced cognitive impairment in rats., PLoS One. 8:e82016.
Masullo, Laura; Mariotti, Letizia; Alexandre, Nicolas; Freire-Pritchett, Paula; Boulanger, Jerome; Tripodi, Marco;,Genetically Defined Functional Modules for Spatial Orienting in the Mouse Superior Colliculus, Current biology : CB Vol.29, 2019
Polenghi A, Nieus T, Guazzi S, Gorostiza P, Petrini EM, Barberis A.,Kainate Receptor Activation Shapes Short-Term Synaptic Plasticity by Controlling Receptor Lateral Mobility at Glutamatergic Synapses, Cell Rep. 2020 Jun 9;31(10):107735. doi: 10.1016/j.celrep.2020.107735.
Stepien BK, Naumann R, Holtz A, Helppi J, Huttner WB, Vaid S.,Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion, Curr Biol. 2020 Nov 2;30(21):4227-4237.e5. doi: 10.1016/j.cub.2020.08.046. Epub 2020 Sep 3.
Schaafsma, W., Zhang, X., van Zomeren, K. C., Jacobs, S., Georgieva, P. B., Wolf, S. A., . . . Eggen, B. J. (2015).,Long-lasting pro-inflammatory suppression of microglia by LPS-preconditioning is mediated by RelB-dependent epigenetic silencing., Brain, Behavior, and Immunity, 48, 205-221. doi:10.1016/j.bbi.2015.03.013 [doi]
Pakarinen E, Danilova T, Võikar V, Chmielarz P, Piepponen P, Airavaara M, Saarma M, Lindahl M.,MANF Ablation Causes Prolonged Activation of the UPR without Neurodegeneration in the Mouse Midbrain Dopamine System, eNeuro. 2020 Feb 19;7(1):ENEURO.0477-19.2019. doi: 10.1523/ENEURO.0477-19.2019. Print 2020 Jan/Feb.
Evans, C., Cook, S. J., Coleman, M. P., & Gilley, J. (2013),MEK inhibitor U0126 reverses protection of axons from wallerian degeneration independently of MEK-ERK signaling., PloS One, 8(10), e76505. doi:10.1371/journal.pone.0076505 [doi]
Brulet, R., Zhu, J., Aktar, M., Hsieh, J., & Cho, K. O. (2017).,Mice with conditional NeuroD1 knockout display reduced aberrant hippocampal neurogenesis but no change in epileptic seizures., Experimental Neurology, 293, 190-198. doi:S0014-4886(17)30098-5 [pii]
Janecek, E., Wilk, E., Schughart, K., Geffers, R., & Strube, C. (2015).,Microarray gene expression analysis reveals major differences between toxocara canis and toxocara cati neurotoxocarosis and involvement of T.canis in lipid biosynthetic processes., International Journal for Parasitology, 45(7), 495-503. doi:10.1016/j.ijpara.2015.02.009 [doi]
Loeffler T, Schilcher I, Flunkert S, Hutter-Paier B.,Neurofilament-Light Chain as Biomarker of Neurodegenerative and Rare Diseases With High Translational Value, Front Neurosci. 2020 Jun 11;14:579. doi: 10.3389/fnins.2020.00579. eCollection 2020.
Palencia, G., Garcia, E., Osorio-Rico, L., Trejo-Solis, C., Escamilla-Ramirez, A., & Sotelo, J. (2015).,Neuroprotective effect of thalidomide on MPTP-induced toxicity., Neurotoxicology, 47, 82-87. doi:10.1016/j.neuro.2015.02.004 [doi]
Markova L, Umek N, Horvat S, Hadžić A, Kuroda M, Pintarič TS, Mrak V, Cvetko E.,Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice, BMC Vet Res. 2020 Jul 17;16(1):247. doi: 10.1186/s12917-020-02459-4.
Heuer, L., Beyerbach, M., Luhder, F., Beineke, A., & Strube, C. (2015).,Neurotoxocarosis alters myelin protein gene transcription and expression, Parasitology Research, 114(6), 2175-2186. doi:10.1007/s00436-015-4407-1 [doi]
Heuer, L., M. Beyerbach, F. Luhder, A. Beineke, and C. Strube. 2015.,Neurotoxocarosis alters myelin protein gene transcription and expression., Parasitol.Res. 114:2175-2186.
Janecek, E., Beineke, A., Schnieder, T., & Strube, C. (2014).,Neurotoxocarosis: Marked preference of toxocara canis for the cerebrum and T. cati for the cerebellum in the paratenic model host mouse, Parasites & Vectors, 7, 194-3305-7-194. doi:10.1186/1756-3305-7-194 [doi]
Janecek, E., A. Beineke, T. Schnieder, and C. Strube. 2014.,Neurotoxocarosis: marked preference of Toxocara canis for the cerebrum and T. cati for the cerebellum in the paratenic model host mouse., Parasit.Vectors. 7:194-3305-7-194.
Adalbert, Robert; Kaieda, Akira; Antoniou, Christina; Loreto, Andrea; Yang, Xiuna; Gilley, Jonathan; Hoshino, Takashi; Uga, Keiko; Makhija, Mahindra T; Coleman, Michael P;,小说HDAC6 Inhibitors Increase Tubulin Acetylation and Rescue Axonal Transport of Mitochondria in a Model of Charcot-Marie-Tooth Type 2F, ACS chemical neuroscience Vol., 2020
Bidinosti, M., Shimshek, D. R., Mollenhauer, B., Marcellin, D., Schweizer, T., Lotz, G. P., . . . Weiss, A. (2012).,Novel one-step immunoassays to quantify alpha-synuclein: Applications for biomarker development and high-throughput screening., The Journal of Biological Chemistry, 287(40), 33691-33705. doi:M112.379792 [pii]
Malik, B., Fernandes, C., Killick, R., Wroe, R., Usardi, A., Williamson, R., . . . Reynolds, C. H. (2012).,Oligomeric amyloid-beta peptide affects the expression of genes involved in steroid and lipid metabolism in primary neurons., Neurochemistry International, 61(3), 321-333. doi:10.1016/j.neuint.2012.05.006 [doi]
艾尔沙德MN,亚伦GB, Naegele JR .)Optogenetic Interrogation of ChR2-Expressing GABAergic Interneurons After Transplantation into the Mouse Brain, Methods Mol Biol. 2021;2191:235-259. doi: 10.1007/978-1-0716-0830-2_15.
Gervois, Pascal; Ratajczak, Jessica; Wolfs, Esther; Vangansewinkel, Tim; Dillen, Yörg; Merckx, Greet; Bronckaers, Annelies; Lambrichts, Ivo,Preconditioning of Human Dental Pulp Stem Cells with Leukocyte- and Platelet-Rich Fibrin-Derived Factors Does Not Enhance Their Neuroregenerative Effect., Stem cells international Vol.2019, 2019
Bistaffa, Edoardo; Rossi, Martina; De Luca, Chiara Maria Giulia; Cazzaniga, Federico; Carletta, Olga; Campagnani, Ilaria; Tagliavini, Fabrizio; Legname, Giuseppe; Giaccone, Giorgio; Moda, Fabio;,Prion Efficiently Replicates in ?-Synuclein Knockout Mice., Molecular neurobiology Vol.56, 2019
Svarcbahs R, Jäntti M, Kilpeläinen T, Julku UH, Urvas L, Kivioja S, Norrbacka S, Myöhänen TT.,Prolyl oligopeptidase inhibition activates autophagy via protein phosphatase 2A, Pharmacol Res. 2020 Jan;151:104558. doi: 10.1016/j.phrs.2019.104558. Epub 2019 Nov 20.
Cabañero D, Ramírez-López A, Drews E, Schmöle A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A, Maldonado R.,Protective role of neuronal and lymphoid cannabinoid CB(2) receptors in neuropathic pain, Elife. 2020 Jul 20;9:e55582. doi: 10.7554/eLife.55582.
古普塔身高;布朗,马克;罗德尔,杰克;艾尔沙德, Muhammad N; Gonzalez, Selena; Luikart, Bryan W; Aaron, Gloster B; Naegele, Janice R;,Restrained Dendritic Growth of Adult-Born Granule Cells Innervated by Transplanted Fetal GABAergic Interneurons in Mice with Temporal Lobe Epilepsy, eNeuro Vol.6,
Gothelf, Y., Abramov, N., Harel, A., & Offen, D. (2014).,Safety of repeated transplantations of neurotrophic factors-secreting human mesenchymal stromal stem cells., Clinical and Translational Medicine, 3, 21-1326-3-21. eCollection 2014. doi:10.1186/2001-1326-3-21 [doi]
Kros, L., Lindeman, S., Eelkman Rooda, O. H. J., Murugesan, P., Bina, L., Bosman, L. W. J., . . . Hoebeek, F. E. (2017).,Synchronicity and rhythmicity of purkinje cell firing during generalized spike-and-wave discharges in a natural mouse model of absence epilepsy., Frontiers in Cellular Neuroscience, 11, 346. doi:10.3389/fncel.2017.00346 [doi]
Di Lieto, A., Rantamaki, T., Vesa, L., Yanpallewar, S., Antila, H., Lindholm, J., . . . Castren, E. (2012).,The responsiveness of TrkB to BDNF and antidepressant drugs is differentially regulated during mouse development., PloS One, 7(3), e32869. doi:10.1371/journal.pone.0032869 [doi]
Di Lieto, A., T. Rantamaki, L. Vesa, S. Yanpallewar, H. Antila, J. Lindholm, M. Rios, L. Tessarollo, and E. Castren. 2012.,The responsiveness of TrkB to BDNF and antidepressant drugs is differentially regulated during mouse development., PLoS One. 7:e32869.
Kostic, Milos; Paridaen, Judith T M L; Long, Katherine R; Kalebic, Nereo; Langen, Barbara; Grübling, Nannette; Wimberger, Pauline; Kawasaki, Hiroshi; Namba, Takashi; Huttner, Wieland B,YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex., Cell reports Vol.27, 2019

Oncology

Healy, M. E., Chow, J. D., Byrne, F. L., Breen, D. S., Leitinger, N., Li, C., . . . Hoehn, K. L. (2015).,Dietary effects on liver tumor burden in mice treated with the hepatocellular carcinogen diethylnitrosamine., Journal of Hepatology, 62(3), 599-606. doi:10.1016/j.jhep.2014.10.024 [doi]
Healy, M. E., Lahiri, S., Hargett, S. R., Chow, J. D., Byrne, F. L., Breen, D. S., . . . Hoehn, K. L. (2016).,Dietary sugar intake increases liver tumor incidence in female mice., Scientific Reports, 6, 22292. doi:10.1038/srep22292 [doi]
Bransi, A., Salgado, O. C., Beffinger, M., Milo, K., Silina, K., Yagita, H., . . . van den Broek, M. (2015).,Rational combination of immunotherapies with clinical efficacy in mice with advanced cancer., Cancer Immunology Research, 3(11), 1279-1288. doi:10.1158/2326-6066.CIR-15-0103-T [doi]
Barrett, J. A., Cai, H., Miao, J., Khare, P. D., Gonzalez, P., Dalsing-Hernandez, J., . . . Lebel, F. (2018).,Regulated intratumoral expression of IL-12 using a RheoSwitch therapeutic system((R)) (RTS((R))) gene switch as gene therapy for the treatment of glioma., Cancer Gene Therapy, 25(5-6), 106-116. doi:10.1038/s41417-018-0019-0 [doi]
Suckow, M. A., Wolter, W. R., & Duffield, G. E. (2017).,The impact of environmental light intensity on experimental tumor growth., Anticancer Research, 37(9), 4967-4971. doi:37/9/4967 [pii]
Patel, A., Anderson, J., Kraft, D., Finnon, R., Finnon, P., Scudamore, C. L., . . . Badie, C. (2016),The influence of the CTIP polymorphism, Q418P, on homologous recombination and predisposition to radiation-induced tumorigenesis (mainly rAML) in mice., Radiation Research, 186(6), 638-649. doi:10.1667/RR14495.1 [doi]
Brighenti, E., Giannone, F. A., Fornari, F., Onofrillo, C., Govoni, M., Montanaro, L., . . . Derenzini, M. (2016).,Therapeutic dosages of aspirin counteract the IL-6 induced pro-tumorigenic effects by slowing down the ribosome biogenesis rate., Oncotarget, 7(39), 63226-63241. doi:10.18632/oncotarget.11441 [doi]
O’rourke, k . P。Loizou E, Livshits, G。,Schatoff, E. M., Baslan, T., Manchado, E., . . . Lowe, S. W. (2017).,Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer., Nature Biotechnology, 35(6), 577-582. doi:10.1038/nbt.3837 [doi]

Toxicology

Smeyne, R. J., Breckenridge, C. B., Beck, M., Jiao, Y., Butt, M. T., Wolf, J. C., . . . Botham, P. A. (2016).,Assessment of the effects of MPTP and paraquat on dopaminergic neurons and microglia in the substantia nigra pars compacta of C57BL/6 mice., PloS One, 11(10), e0164094. doi:10.1371/journal.pone.0164094 [doi]
Whitemarsh, R. C., Tepp, W. H., Bradshaw, M., Lin, G., Pier, C. L., Scherf, J. M., . . . Pellett, S. (2013).,Characterization of botulinum neurotoxin A subtypes 1 through 5 by investigation of activities in mice, in neuronal cell cultures, and in vitro., Infection and Immunity, 81(10), 3894-3902. doi:10.1128/IAI.00536-13 [doi]
Heiss, Gregor; Ploetz, Evelyn; Voith von Voithenberg, Lena; Viswanathan, Ramya; Glaser, Samson; Schluesche, Peter; Madhira, Sushi; Meisterernst, Michael; Auble, David T; Lamb, Don C;,Conformational changes and catalytic inefficiency associated with Mot1-mediated TBP-DNA dissociation., Nucleic acids research Vol.47, 2019
Kolomansky A, Hiram-Bab S, Ben-Califa N, Liron T, Deshet-Unger N, Mittelman M, Oster HS, Rauner M, Wielockx B, Neumann D, Gabet Y.,Erythropoietin Mediated Bone Loss in Mice Is Dose-Dependent and Mostly Irreversible, Int J Mol Sci. 2020 May 27;21(11):3817. doi: 10.3390/ijms21113817.
Springer, Andrea; Heuer, Lea; Janecek-Erfurth, Elisabeth; Beineke, Andreas; Strube, Christina,Histopathological characterization of Toxocara canis- and T. cati-induced neurotoxocarosis in the mouse model., Parasitology research Vol.118, 2019
Zhou, H., Malik, M. A., Arab, A., Hill, M. T., & Shikanov, A. (2015),Hydrogel based 3-dimensional (3D) system for toxicity and high-throughput (HTP) analysis for cultured murine ovarian follicles., PloS One, 10(10), e0140205. doi:10.1371/journal.pone.0140205 [doi]
Hoek-van den Hil, E. F., van Schothorst, E. M., van der Stelt, I., Hollman, P. C., Keijer, J., & Rietjens, I. M. (2015),Quercetin tests negative for genotoxicity in transcriptome analyses of liver and small intestine of mice., Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research Association, 81, 34-39. doi:10.1016/j.fct.2015.04.005 [doi]
Myhre, O., Eide, D. M., Kleiven, S., Utkilen, H. C., & Hofer, T. (2018),Repeated five-day administration of L-BMAA, microcystin-LR, or as mixture, in adult C57BL/6 mice - lack of adverse cognitive effects., Scientific Reports, 8(1), 2308-018-20327-y. doi:10.1038/s41598-018-20327-y [doi]
Win, S., Than, T. A., Le, B. H., Garcia-Ruiz, C., Fernandez-Checa, J. C., & Kaplowitz, N. (2015).,Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity., Journal of Hepatology, 62(6), 1367-1374. doi:10.1016/j.jhep.2015.01.032 [doi]
Kendziorski, J. A., Kendig, E. L., Gear, R. B., & Belcher, S. M. (2012).,应变诱导特定的子宫积脓和与众不同ces in immune responsiveness in mice exposed to 17alpha-ethinyl estradiol or the endocrine disrupting chemical bisphenol A, Reproductive Toxicology (Elmsford, N.Y.), 34(1), 22-30. doi:10.1016/j.reprotox.2012.03.001 [doi]
Kendziorski, J. A., & Belcher, S. M. (2015).,Strain-specific induction of endometrial periglandular fibrosis in mice exposed during adulthood to the endocrine disrupting chemical bisphenol A., A. Reproductive Toxicology (Elmsford, N.Y.), 58, 119-130. doi:10.1016/j.reprotox.2015.08.001 [doi]
Meier, D. T., Entrup, L., Templin, A. T., Hogan, M. F., Mellati, M., Zraika, S., . . . Kahn, S. E. (2016),The S20G substitution in hIAPP is more amyloidogenic and cytotoxic than wild-type hIAPP in mouse islets., Diabetologia, 59(10), 2166-2171. doi:10.1007/s00125-016-4045-x [doi]

Vaccines

Aminzadeh A, Tiwari MK, Mamah Mustapha SS, Navarrete SJ, Henriksen AB, Møller IM, Krogfelt KA, Bjerrum MJ, Jørgensen R.,Detoxification of toxin A and toxin B by copper ion-catalyzed oxidation in production of a toxoid-based vaccine against Clostridioides difficile, Free Radic Biol Med. 2020 Nov 20;160:433-446. doi: 10.1016/j.freeradbiomed.2020.08.021. Epub 2020 Aug 27.