• Background strain: Long Evans Hooded
• Cre recombinase driven by endogenous Somatostatin promoter
• No observed ectopic expression of cre
• Targeted insertion eliminates possible gene disruption that may occur in random insertion technologies such as BAC

Availability:Live colony
Zygosity genotype:Homozygous

这个模型表达cre-recombinase欺诈trol of the endogenous somatostatin promoter enabling specific expression in somatostatin neurons. This model possesses a targeted insertion of (IRES)-cre immediately after the translational stop in the open reading frame of Sst. The Sst-Cre rat is useful for applications requiring tissue specific expression, including optogenetics and breeding with transgenic floxed lines.